Home > Press > Alzheimer’s Association Awards Grant To University Of Utah’s Brain Institute
The Alzheimer's Association has awarded University of Utah Brain Institute investigator Gang Liu, Ph.D., a $240,000 grant to study why Alzheimer's patients have higher levels of metal ions such as aluminum, copper, and iron in their brains. The research could lead to new treatments using nanotechnology and slow down the progression of the disease.
Alzheimer’s Association Awards Grant To University Of Utah’s Brain Institute
Salt Lake City, UT | Posted on August 28th, 2007
According to Linda Blonsley, executive director of the Alzheimer Association's Utah Chapter, more than 26 million people worldwide have Alzheimer's disease, and the number is expected to reach 100 million by 2050. It is the most common form of dementia among people over age 65 and causes progressive and irreversible damage to thought, memory, and language.
"Despite our best attempts, the cause of Alzheimer's disease is still not completely understood and a viable cure is not available," said Blonsley. "We are pleased to be a partner with the University of Utah and are optimistic about the research coming out of the Brain Institute."
Liu, a research assistant professor in the University's Radiology Division and an investigator with the University's Brain Institute, said, "We know oxidative stress is present in the early stages of Alzheimer's disease and that stress is often caused by high levels of metal ions in the body. We want to find a safe, effective way to reduce the level of ions in the brain."
Liu, along with colleague Ping Men, M.D., will evaluate whether a process known as chelation therapy can be used to reduce amount of metal ions in the brain. Past attempts at chelation therapy have been hindered because of side effects and the inability to target specific tissue.
"Our research focuses on using chelation therapy coupled with nanoparticle delivery technology, which targets the brain and causes less toxic side effects," said Liu. "The chelation systems are designed to leave the brain after binding excess metal ions which helps reduce adverse effects of the therapy."
He says the process also could be used to treat other neurodegenerative diseases such as Parkinson's disease and Huntington's disease. The University has applied for a patent on the technology.
About University of Utah
The Brain Institute at the University of Utah is a new and growing research endeavor for research, Innovation and education to decipher the fundamental basis of brain function. With more than 100 faculty investigators in neuroscience-related disciplines, the University of Utah has great existing depth in neuroscience research and clinical care.
For more information, please click here
Gang Liu, Ph.D.
research assistant professor
Copyright © University of Utah
If you have a comment, please Contact
Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.
NYU Researchers Break Nano Barrier to Engineer the First Protein Microfiber October 23rd, 2014
Iranian Scientists Apply Nanotechnology to Produce Surgery Suture October 23rd, 2014
RF Heating of Magnetic Nanoparticles Improves the Thawing of Cryopreserved Biomaterials October 23rd, 2014
Sopping up proteins with thermosponges: Researchers develop novel nanoparticle platform that proves effective in delivering protein-based drugs October 22nd, 2014
Iran to Hold 3rd Int'l Engineering Materials, Metallurgy Conference October 25th, 2014
Haydale Secures Exclusive Development and Supply Agreement with Tantec A/S: New reactors to be built and commissioned by Tantec A/S represent another step forward towards the commercialisation of graphene October 24th, 2014
QuantumWise guides the semiconductor industry towards the atomic scale October 24th, 2014
Strengthening thin-film bonds with ultrafast data collection October 23rd, 2014
Special UO microscope captures defects in nanotubes: University of Oregon chemists provide a detailed view of traps that disrupt energy flow, possibly pointing toward improved charge-carrying devices October 21st, 2014
Crystallizing the DNA nanotechnology dream: Scientists have designed the first large DNA crystals with precisely prescribed depths and complex 3D features, which could create revolutionary nanodevices October 20th, 2014
QD Vision Wins Prestigious Presidential Green Chemistry Challenge Award from the U.S. Environmental Protection Agency October 16th, 2014
Beyond LEDs: Brighter, new energy-saving flat panel lights based on carbon nanotubes - Planar light source using a phosphor screen with highly crystalline single-walled carbon nanotubes (SWCNTs) as field emitters demonstrates its potential for energy-efficient lighting device October 14th, 2014