Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > News > Artificial nanopores take analyte pulse

July 31st, 2007

Artificial nanopores take analyte pulse

Abstract:
Resistive pulse sensing represents a very attractive method for identifying and quantifying biomedical species such as drugs, DNA, proteins, and viruses in solution. This method involves measuring changes in the ionic current across a membrane containing a single nanometer-sized pore that separates two electrolyte solutions. As the biological analytes make their way through the pore, they induce transient downward current pulses in the ionic current by transiently blocking the nanopore.

The frequency, duration, and magnitude of the current pulse contain telltale information that aids the identification and quantification of the analyte. A biological nanopore, α-hemolysin, supported by a lipid bilayer membrane, works well in the detection of various analytes. However, a major impediment to this system is its lack of mechanical robustness. Indeed, these biological membranes tend to rupture within a few hours, thus precluding their application in practical sensing devices.

Now a team of researchers at the University of Florida have come up with a major breakthrough that will aid the reproducible fabrication of robust synthetic single-nanopore membranes ("A Method for Reproducibly Preparing Synthetic Nanopores for Resistive-Pulse Biosensors").

Source:
nanowerk.com

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

Sensors

Leti to Demo Wristband with Embedded Sensors to Diagnose Sleep Apnea: APNEAband, Which Will Be Demonstrated at CES 2018, Also Monitors Mountain Sickness, Dehydration, Dialysis Treatment Response and Epileptic Seizures December 12th, 2017

Leti Develops World’s First Micro-Coolers for CERN Particle Detectors: Leti Design, Fabrication and Packaging Expertise Extends to Very Large Scientific Instruments December 11th, 2017

Graphene oxide making any material suitable to create biosensors: Scientists from Tomsk Polytechnic University have developed a new tool for biomedical research focused on single-cell investigation November 27th, 2017

The stacked color sensor: True colors meet minimization November 16th, 2017

Discoveries

Sandia researchers make solid ground toward better lithium-ion battery interfaces: Reducing the traffic jam in batteries December 13th, 2017

Perking up and crimping the 'bristles' of polyelectrolyte brushes December 13th, 2017

Columbia engineers create artificial graphene in a nanofabricated semiconductor structure: Researchers are the first to observe the electronic structure of graphene in an engineered semiconductor; finding could lead to progress in advanced optoelectronics and data processing December 13th, 2017

Untangling DNA: Researchers filter the entropy out of nanopore measurements December 8th, 2017

Announcements

Sandia researchers make solid ground toward better lithium-ion battery interfaces: Reducing the traffic jam in batteries December 13th, 2017

Perking up and crimping the 'bristles' of polyelectrolyte brushes December 13th, 2017

Columbia engineers create artificial graphene in a nanofabricated semiconductor structure: Researchers are the first to observe the electronic structure of graphene in an engineered semiconductor; finding could lead to progress in advanced optoelectronics and data processing December 13th, 2017

Leti to Demo Wristband with Embedded Sensors to Diagnose Sleep Apnea: APNEAband, Which Will Be Demonstrated at CES 2018, Also Monitors Mountain Sickness, Dehydration, Dialysis Treatment Response and Epileptic Seizures December 12th, 2017

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project