Nanotechnology Now

Our NanoNews Digest Sponsors


Heifer International

Wikipedia Affiliate Button

Home > News > Artificial nanopores take analyte pulse

July 31st, 2007

Artificial nanopores take analyte pulse

Abstract:
Resistive pulse sensing represents a very attractive method for identifying and quantifying biomedical species such as drugs, DNA, proteins, and viruses in solution. This method involves measuring changes in the ionic current across a membrane containing a single nanometer-sized pore that separates two electrolyte solutions. As the biological analytes make their way through the pore, they induce transient downward current pulses in the ionic current by transiently blocking the nanopore.

The frequency, duration, and magnitude of the current pulse contain telltale information that aids the identification and quantification of the analyte. A biological nanopore, α-hemolysin, supported by a lipid bilayer membrane, works well in the detection of various analytes. However, a major impediment to this system is its lack of mechanical robustness. Indeed, these biological membranes tend to rupture within a few hours, thus precluding their application in practical sensing devices.

Now a team of researchers at the University of Florida have come up with a major breakthrough that will aid the reproducible fabrication of robust synthetic single-nanopore membranes ("A Method for Reproducibly Preparing Synthetic Nanopores for Resistive-Pulse Biosensors").

Source:
nanowerk.com

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

Sensors

Electron 'spin control' of levitated nanodiamonds could bring advances in sensors, quantum information processing July 20th, 2016

Easier, faster, cheaper: A full-filling approach to making nanotubes of consistent quality: Approach opens a straightforward route for engineering the properties of single-wall carbon nanotubes July 19th, 2016

Researchers invent 'smart' thread that collects diagnostic data when sutured into tissue: Advances could pave way for new generation of implantable and wearable diagnostics July 18th, 2016

UNIST engineers octopus-inspired smart adhesive pads July 15th, 2016

Discoveries

Russian physicists discover a new approach for building quantum computers: Physicists find a way of 'bundling together' multiple elements of a quantum computer July 24th, 2016

A 'smart dress' for oil-degrading bacteria July 24th, 2016

New remote-controlled microrobots for medical operations July 23rd, 2016

New superconducting coil improves MRI performance: UH-led research offers higher resolution, shorter scan time July 23rd, 2016

Announcements

Russian physicists discover a new approach for building quantum computers: Physicists find a way of 'bundling together' multiple elements of a quantum computer July 24th, 2016

A 'smart dress' for oil-degrading bacteria July 24th, 2016

New remote-controlled microrobots for medical operations July 23rd, 2016

New superconducting coil improves MRI performance: UH-led research offers higher resolution, shorter scan time July 23rd, 2016

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







Car Brands
Buy website traffic