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Home > News > Nanoparticles send peptides round the twist

July 18th, 2007

Nanoparticles send peptides round the twist

Abstract:
Nanoparticles with flexible side chains cause peptides to adopt a helical form, making them promising anticancer agents.

Vincent Rotello and colleagues at the University of Massachusetts, Amherst, US, used functionalised gold nanoparticles to persuade a tetraaspartate peptide (TAP) to form an alpha-helix. In the absence of the nanoparticles, the peptide forms a random coil ("Binding and templation of nanoparticle receptors to peptide -helices through surface recognition" - free access article).

Source:
nanowerk.com

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"Binding and templation of nanoparticle receptors to peptide -helices through surface recognition" (free access article)

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