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Home > News > Developing nanotechnology noses to 'smell' cancer

July 1st, 2007

Developing nanotechnology noses to 'smell' cancer

Biomarkers are of increasing importance in modern medicine for the purpose of early detection and diagnosis of a disease, for instance cancer. Biomarkers are mostly protein molecules that can be measured in blood, other body fluids, and tissues to assess the presence or state of a disease. For example, the presence of an antibody may indicate an infection or an antigen, such as PSA, might indicate the presence of prostate-specific cancer cells. Although protein-based approaches to early detection and diagnosis of cancer have a clear advantage over other, more invasive, methods, protein detection is a challenging problem owing to the structural diversity and complexity of the target analytes. State-of-the-art detection methods have limited application due to their high production cost and instability. Another limitation of current proteomic diagnostics is the limitation of arrays to one or a few markers only; in other words, you can only test for the specific markers that you are looking for and not generally measure levels of proteins in your blood in order to detect anomalies. A novel nanotechnology based protein detector array could change that.


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