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Home > News > Fluorescent imaging of single molecules in live cells uncovers details of gene expression, structural proteins, and molecular motors

June 4th, 2007

Fluorescent imaging of single molecules in live cells uncovers details of gene expression, structural proteins, and molecular motors

Abstract:
Ultimately, the semiconductor nanoparticles known as quantum dots may turn out to be the best probes, according to several scientists. But quantum dots currently fall short, too. The main problem with them is their size: They're too big. The nanoparticle itself is about the same size as GFP, but to make quantum dots water soluble and to attach them to biomolecules, they must be coated with various agents that nearly double their size. "They become so large that what you can do with them is limited," Ha says.

Source:
pubs.acs.org

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