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Home > News > An ultrasensitive method for weighing cells could lead to a cheap and easy-to-use diagnostic device.

May 1st, 2007

An ultrasensitive method for weighing cells could lead to a cheap and easy-to-use diagnostic device.

Abstract:
Instead of labeling the targeted cells with antibodies, Manalis uses nanoparticles. "The same approach can be used for detection by mass," says Manalis, "except the fluorescent molecule would be replaced by a nanoparticle. Instead of making certain cells brighter, they can be made heavier so they stand out from the background."

"It's a nice nonoptical way to do detection," says Stephen Quake, a professor of biological engineering at Stanford University. Quake says that the method could be particularly useful for applications that require small and portable devices. And he says that although more work is necessary to determine the best possible use of the detection method, the "research is promising enough that I'm very exited about it."

Source:
technologyreview.com

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