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February 12th, 2007

DNA-encoded antibody libraries

Abstract:
During the past several years, breakthroughs in genomic and proteomic technologies have enabled researchers to more clearly identify the biochemical networks that malfunction when a healthy cell becomes malignant.

Now, James Health, Ph.D., and colleagues at the California Institute of Technology have developed a new approach to genomic and proteomic analysis, one that detects messenger RNA (mRNA), proteins, and even whole cells simultaneously on a single glass slide.

This new method, described in the Journal of the American Chemical Society, stands to simplify efforts to combine genomic and proteomic analyses in the same experiment. Heath is a co-principal investigator of the Nanosystems Biology Cancer Center (NSBCC) CCNE.

Source:
news-medical.net

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