Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > News > Manuscript Demonstrates DNA Delivery and Expression in the Mouse Retina

January 9th, 2007

Manuscript Demonstrates DNA Delivery and Expression in the Mouse Retina

Abstract:
Copernicus Therapeutics, Inc. announced today that a research team at University of Oklahoma Health Sciences Center, led by Dr. Muna Naash, professor of Cell Biology, demonstrated that Copernicus' DNA nanoparticles safely and effectively deliver and express DNA in the rods and cones of the mouse retina. According to Dr. Naash's team, current data indicate that greater than 95% of these retinal cells expressed the DNA nanoparticle and there was no evidence of toxicity. These findings, published on December 20, 2006 in the journal PLoS ONE, have significant implications for the development of DNA-based therapeutics for various eye disorders, including retinitis pigmentosa and macular degeneration company officials said.

"These exciting results suggest that genetic replacement therapy is feasible for various eye diseases," said Robert C. Moen, M.D., Ph.D., president and CEO of Copernicus. "The Copernicus DNA nanoparticle formulation is safe and effective and permits a non-viral approach to treat human disease by introducing a normal copy of the underlying gene that is responsible for the disease process. In addition to corrective therapy for genetic diseases such as retinitis pigmentosa, nucleic acid nanoparticles may provide effective treatments for more complex disorders such as diabetic retinopathy, macular degeneration, and various diseases that injure ganglion cells and the optic nerve."

Source:
businesswire.com

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

Nanomedicine

New, old science combine to make faster medical test: Nanoparticles and Faraday rotation allow faster diagnoses January 23rd, 2017

New research helps to meet the challenges of nanotechnology: Research helps to make the most of nanoscale catalytic effects for nanotechnology January 20th, 2017

Chemists Cook up New Nanomaterial and Imaging Method: Nanomaterials can store all kinds of things, including energy, drugs and other cargo January 19th, 2017

'5-D protein fingerprinting' could give insights into Alzheimer's, Parkinson's January 19th, 2017

Discoveries

The speed limit for intra-chip communications in microprocessors of the future January 23rd, 2017

New, old science combine to make faster medical test: Nanoparticles and Faraday rotation allow faster diagnoses January 23rd, 2017

Traffic jam in empty space: New success for Konstanz physicists in studying the quantum vacuum January 22nd, 2017

A big nano boost for solar cells: Kyoto University and Osaka Gas effort doubles current efficiencies January 21st, 2017

Announcements

The speed limit for intra-chip communications in microprocessors of the future January 23rd, 2017

New, old science combine to make faster medical test: Nanoparticles and Faraday rotation allow faster diagnoses January 23rd, 2017

Traffic jam in empty space: New success for Konstanz physicists in studying the quantum vacuum January 22nd, 2017

A big nano boost for solar cells: Kyoto University and Osaka Gas effort doubles current efficiencies January 21st, 2017

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project