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January 18th, 2006
In a stroke of serendipity, chemists at Rutgers University have discovered a one-pot reaction in which 18 molecular components react sequentially to form, in high yield, a cavernous, covalent molecule that potentially could encapsulate other, smaller molecules.
Although a couple of covalent "nanocontainer" molecules have been synthesized previously, the new route is operationally far more efficient, and it also is atom-efficient. These features could be advantageous in potential applications such as drug delivery, separation science, catalysis, and sensing.
Chemical & Engineering News
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