Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > CMU Dendron Based Agents May Treat Breast Cancer, Osteoporosis

Abstract:
The study of nanosize particles as drug delivery agents to treat breast cancer and osteoporosis may help millions of U.S. women.

CMU Dendron Based Agents May Treat Breast Cancer, Osteoporosis

Mount Pleasant, MI | March 16, 2005

Central Michigan University faculty chemist Choon Young Lee may help more than 120,000 U.S. women who are diagnosed with breast cancer each year. In addition, her work may improve the lives of 10 million Americans with osteoporosis, mostly women, and the 34 million more who have low bone mass. Osteoporosis is a progressive disease that causes bones to become thin and porous, increasing the risk for fractures.

“The investigation of new agents to treat breast cancer and osteoporosis are the foundation of effective treatment methods,” said Lee.

Both breast cancer and osteoporosis are closely related to estrogen function, and half of all breast cancers are hormone dependent.

Lee’s work is involved with biologically linking estrogen to dendrons — pie-shaped dendrimers — to help provide a foundation for new treatment methods. Dendrimers, three-dimensional particles so small they allow the creation of new structures, literally atom-by-atom, have applications in biotechnology, pharmaceuticals, clothing, electronics and more.

Lee will submit a library of possible steroidal, dendron-modified estradiols (an estrogen) as therapeutic agents for screening by the National Cancer Institute for potential benefits in treating hormone-dependent breast cancer and osteoporosis.

The current non-steroidal treatments for breast cancer and osteoporosis have high rates of side effects. By using dendron-based steroidal agents, a higher potency of the drug could be delivered at a lower dose with few or no side effects to patients.

“A higher potency means that a lower dose of the agent is needed to induce the same effect,” said Lee. “An ideal agent to prevent and treat both osteoporosis and breast cancer should stimulate estrogen receptors in the bone tissue and block them in breast tissue so a tumor would stop growing.

Choon works with undergraduate students, giving them hands-on experience with an emerging field of study.

Lee’s work is supported by a $25,000 CMU research grant.



Contact:
Choon Young Lee
(989) 774-3289

Copyright © Central Michigan University

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

Possible Futures

Nanocatalysis for organic chemistry: This research article by Dr. Qien Xu et al. is published in Current Organic Chemistry, Volume 20, Issue 19, 2016 August 30th, 2016

Continuous roll-process technology for transferring and packaging flexible LSI August 29th, 2016

Designing ultrasound tools with Lego-like proteins August 29th, 2016

A nanoscale wireless communication system via plasmonic antennas: Greater control affords 'in-plane' transmission of waves at or near visible light August 27th, 2016

Nanomedicine

Designing ultrasound tools with Lego-like proteins August 29th, 2016

Nanofiber scaffolds demonstrate new features in the behavior of stem and cancer cells August 25th, 2016

Johns Hopkins scientists track metabolic pathways to find drug combination for pancreatic cancer August 25th, 2016

50 years after the release of the film 'Fantastic Voyage,' science upstages fiction: Science upstages fiction with nanorobotic agents designed to travel in the human body to treat cancer August 25th, 2016

Announcements

University of Akron researchers find thin layers of water can become ice-like at room temperature: Results could lead to an assortment of anti-friction solutions August 30th, 2016

Nanocatalysis for organic chemistry: This research article by Dr. Qien Xu et al. is published in Current Organic Chemistry, Volume 20, Issue 19, 2016 August 30th, 2016

Continuous roll-process technology for transferring and packaging flexible LSI August 29th, 2016

Meteorite impact on a nano scale August 29th, 2016

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







Car Brands
Buy website traffic