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Home > News > Nanoparticle technique detects Alzheimer's-related proteins

February 1st, 2005

Nanoparticle technique detects Alzheimer's-related proteins

Abstract:
"We have demonstrated the first diagnostic test for the potential Alzheimer's biomarker known as an ADDL," said Chad Mirkin, director of Northwestern's Institute for Nanotechnology. "This protein is only 5 nm wide and present in cerebrospinal fluid at very low concentration, making it difficult to detect. Our bio-barcode-amplification technology, which is a million times more sensitive than any other diagnostic technology, can accurately identify ADDLs even in CSF."

The bio-barcode-amplification technique uses 30 nm-diameter gold nanoparticles and magnetic microparticles.

Source:
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