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December 16th, 2004

Small spheres, big potential

Abstract:
The integration of nanotechnology and biophotonics techniques has resulted in development of nanoparticle platforms that will impact biophotonics applications such as bioimaging, biosensing, genomics and proteomics, light-activated therapy, and tissue engineering.

These platforms include 20- to 40-nm-diameter silica bubbles that can have molecules attached to the outside or encapsulated inside. Silica-based nanoparticle platforms provide a number of advantages: the nanoparticles can be made under mild conditions that don't damage biological activity; the nanometer-scale size of the particles minimizes interaction with the immune system; the silica shell can be functionalized for coupling of biologics; silica nanoparticles are stable in biological environments; and silica-based nanoparticles are optically transparent.

Source:
oemagazine

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