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July 12th, 2004

High-yield path to dendrimers

A copper-catalyzed fusion reaction of azides and alkynes to form 1,2,3-triazoles has been applied to dendrimer synthesis for the first time and has been found to give dendrimer yields higher than those achieved with any other reactions. Dendrimers are large, globular molecules comprising several branches - or dendrons - emanating from a central core. A range of functional groups can be put on dendrimer surfaces to endow them with specific chemical and physical properties.


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