Abstract:
Cell-to-cell communication is achieved by a variety of means, from diffusible signals and gap junctions to the thin actin-based cellular extensions termed cytonemes seen in Drosophila. In the February 13 Science, Amin Rustom and colleagues from University of Heidelberg report ultrafine cell-to-cell contacts in cultured cells, termed tunneling nanotubes (TNTs), that facilitate organelle transport between cells.