Abstract:
Current vascular biomaterials such as Dacron and polytetrafluroethylene are designed with microscale topographies, ignoring the fact that native vascular tissue has a topography ranging from micron to nanometre. Previously, it has been shown that changing the surface topography from the micron to nanometre scale results in increased bone cell functions. Researchers at Purdue University's Cell Biomechanics and Nanostructured Biomaterials Lab are using these design parameters to develop synthetic nanostructured polymeric biomaterials that have enhanced cytocompatibility properties.