Nanotechnology Now

Our NanoNews Digest Sponsors
Heifer International



Home > Press > Jet-printing microfluidic devices on demand

Abstract:
Jet-printing microfluidic devices on demand1 – a new paper from engineering and biomedical scientists at the University of Oxford and spin-out company iotaSciences Ltd – describes a game-changing method to generate cell-friendly microfluidic devices on demand. This innovative protocol offers significant benefits to biology and biomedicine, enabling simple, contactless fabrication of microfluidic circuits in minutes – almost as quickly as the circuit pattern can be drawn on paper – using truly cell-friendly materials; standard Petri dishes and culture media.

Jet-printing microfluidic devices on demand

Oxford, UK | Posted on November 6th, 2020

The pioneering jet-printing method stems from the recognition that gravity becomes irrelevant at the microscale. In the everyday world, objects are invariably made with solids; building complex structures out of liquids, which would collapse into puddles and drain away, is not feasible. Using microjets to fabricate microfluidic devices takes advantage of the interfacial forces that dominate in the microworld. In this paper, the method was used to successfully clone cells by limiting dilution in a way that beats the Poisson limit, to subculture adherent cells, and to feed arrays of cells continuously for a week in sub-microliter chambers. Liquid flows were driven through conduits with and without external pumps, and circuits reconfigured to open and close ‘fluidic valves’ at will. The diversity and flexibility of this approach is expected to lead to widespread adoption of the technique for a variety of applications in biomedicine.

1 Soitu, C, Stovall-Kurtz, N., Deroy, C., Castrejón-Pita, A.A., Cook, P.R., and Walsh, E.J. (2020). Jet-printing microfluidic devices on demand. Advanced Science 10.1002/advs.202001854.

####

About iotaSciences
This research was supported by iotaSciences, a spin-out company from the University of Oxford. iotaSciences is exploiting biomicrofluidic technology to deliver innovative solutions for biological workflows, including single-cell cloning for cell line development.

For more information, please click here

Contacts:
Sarah Ballard
kdm communications limited
St Neots, UK

Tel. +44 (0) 1480 405333
Fax: +44 (0) 1480 477833

Copyright © iotaSciences

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related Links

This open access paper was published on the 26th of October and is available to download at:

Related News Press

News and information

Biology’s hardest working pigments and ‘MOFs’ might just save the climate: A range of processes that currently depend on fossil fuels but are really hard to electrify will depend on the development of genuinely clean fuels, and for that to happen, much more efficient catalysts wi July 22nd, 2022

Generating power where seawater and river water meet July 22nd, 2022

First electric nanomotor made from DNA material: Synthetic rotary motors at the nanoscale perform mechanical work July 22nd, 2022

At the water’s edge: Self-assembling 2D materials at a liquid–liquid interface: Scientists find a simple way to produce heterolayer coordination nanosheets, expanding the diversity of 2D materials July 22nd, 2022

Microfluidics/Nanofluidics

Oregon State University research pushes closer to new therapy for pancreatic cancer May 6th, 2022

Directly into the brain: A 3D multifunctional and flexible neural interface: Novel design of brain chip implant allows for measuring neuronal activity while simultaneously delivering drugs to the implant site October 1st, 2021

Confined magnetic colloidal system for controllable fluid transport March 16th, 2021

Stretching diamond for next-generation microelectronics January 5th, 2021

Possible Futures

Biology’s hardest working pigments and ‘MOFs’ might just save the climate: A range of processes that currently depend on fossil fuels but are really hard to electrify will depend on the development of genuinely clean fuels, and for that to happen, much more efficient catalysts wi July 22nd, 2022

Generating power where seawater and river water meet July 22nd, 2022

First electric nanomotor made from DNA material: Synthetic rotary motors at the nanoscale perform mechanical work July 22nd, 2022

At the water’s edge: Self-assembling 2D materials at a liquid–liquid interface: Scientists find a simple way to produce heterolayer coordination nanosheets, expanding the diversity of 2D materials July 22nd, 2022

Nanomedicine

How different cancer cells respond to drug-delivering nanoparticles: The findings of a large-scale screen could help researchers design nanoparticles that target specific types of cancer July 22nd, 2022

Biology’s hardest working pigments and ‘MOFs’ might just save the climate: A range of processes that currently depend on fossil fuels but are really hard to electrify will depend on the development of genuinely clean fuels, and for that to happen, much more efficient catalysts wi July 22nd, 2022

Study reveals new mode of triggering immune responses July 15th, 2022

UNC Charlotte-led team invents new anticoagulant platform, offering hope for advances for heart surgery, dialysis, other procedures July 15th, 2022

Discoveries

HKU physicists found signatures of highly entangled quantum matter July 22nd, 2022

How different cancer cells respond to drug-delivering nanoparticles: The findings of a large-scale screen could help researchers design nanoparticles that target specific types of cancer July 22nd, 2022

The best semiconductor of them all? Researchers have found a material that can perform much better than silicon. The next step is finding practical and economic ways to make it July 22nd, 2022

Buckyballs on gold are less exotic than graphene July 22nd, 2022

Announcements

Quantum computer works with more than zero and one: Quantum digits unlock more computational power with fewer quantum particles July 22nd, 2022

Biology’s hardest working pigments and ‘MOFs’ might just save the climate: A range of processes that currently depend on fossil fuels but are really hard to electrify will depend on the development of genuinely clean fuels, and for that to happen, much more efficient catalysts wi July 22nd, 2022

Generating power where seawater and river water meet July 22nd, 2022

First electric nanomotor made from DNA material: Synthetic rotary motors at the nanoscale perform mechanical work July 22nd, 2022

Interviews/Book Reviews/Essays/Reports/Podcasts/Journals/White papers/Posters

Buckyballs on gold are less exotic than graphene July 22nd, 2022

Quantum computer works with more than zero and one: Quantum digits unlock more computational power with fewer quantum particles July 22nd, 2022

Biology’s hardest working pigments and ‘MOFs’ might just save the climate: A range of processes that currently depend on fossil fuels but are really hard to electrify will depend on the development of genuinely clean fuels, and for that to happen, much more efficient catalysts wi July 22nd, 2022

Generating power where seawater and river water meet July 22nd, 2022

Nanobiotechnology

How different cancer cells respond to drug-delivering nanoparticles: The findings of a large-scale screen could help researchers design nanoparticles that target specific types of cancer July 22nd, 2022

Biology’s hardest working pigments and ‘MOFs’ might just save the climate: A range of processes that currently depend on fossil fuels but are really hard to electrify will depend on the development of genuinely clean fuels, and for that to happen, much more efficient catalysts wi July 22nd, 2022

First electric nanomotor made from DNA material: Synthetic rotary motors at the nanoscale perform mechanical work July 22nd, 2022

Study reveals new mode of triggering immune responses July 15th, 2022

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project