Home > Press > New electronic stent could provide feedback and therapy — then dissolve
A multi-tasking stent can measure blood flow, take temperature readings, release drugs and dissolve when it's no longer needed. Credit: Kim lab image, adapted from ACS version |
Abstract:
Every year, an estimated half-million Americans undergo surgery to have a stent prop open a coronary artery narrowed by plaque. But sometimes the mesh tubes get clogged. Scientists report in the journal ACS Nano a new kind of multi-tasking stent that could minimize the risks associated with the procedure. It can sense blood flow and temperature, store and transmit the information for analysis and can be absorbed by the body after it finishes its job.
Doctors have been implanting stents to unblock coronary arteries for 30 years. During that time, the devices have evolved from bare metal, mesh tubes to coated stents that can release drugs to prevent reclogging. But even these are associated with health risks. So researchers have been working on versions that the body can absorb to minimize the risk that a blood clot will form. And now Dae-Hyeong Kim, Seung Hong Choi, Taeghwan Hyeon and colleagues are taking that idea a step further.
The researchers developed and tested in animals a drug-releasing electronic stent that can provide diagnostic feedback by measuring blood flow, which slows when an artery starts narrowing. The device can also heat up on command to speed up drug delivery, and it can dissolve once it's no longer needed.
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The American Chemical Society is a nonprofit organization chartered by the U.S. Congress. With more than 158,000 members, ACS is the world's largest scientific society and a global leader in providing access to chemistry-related research through its multiple databases, peer-reviewed journals and scientific conferences. Its main offices are in Washington, D.C., and Columbus, Ohio.
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Contacts:
Dae-Hyeong Kim, Ph.D.
School of Chemical and Biological Engineering
Institute of Chemical Processes
Seoul National University
Seoul, Republic of Korea
General Inquiries:
Michael Bernstein
202-872-6042
Science Inquiries:
Katie Cottingham, Ph.D.
301-775-8455
Copyright © American Chemical Society
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