Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Microscopy Today 2014 Innovation Award for Leica Microsystems' Super-Resolution System Leica SR GSD 3D: 3D-enabled GSDIM/dSTORM-based Microscope System Wins Again

Left: Leica SR GSD 3D super-resolution system. Right: Super-resolution 3D stack of an oocyte section in false color code stained for the synaptonemal complex protein 3 (SYCP3). Courtesy of M. Lessard, Jackson Lab, Maine, USA
Left: Leica SR GSD 3D super-resolution system. Right: Super-resolution 3D stack of an oocyte section in false color code stained for the synaptonemal complex protein 3 (SYCP3).

Courtesy of M. Lessard, Jackson Lab, Maine, USA

Abstract:
Leica Microsystems' super-resolution system Leica SR GSD 3D is honored with the Microscopy Today 2014 Innovation Award for the capability of acquiring three-dimensional super-resolution images. Microscopy Today, the journal of the Microscopy Society of America, annually distinguishes ten achievements that are selected for their importance and usefulness to the microscopy community. Since its market launch in 2011, the GSDIM/dSTORM system Leica SR GSD and its successor Leica SR GSD 3D won several prizes - among them "The Scientist Magazine - Top Ten Innovations Award" in 2011 and 2013, as well as the "R&D 100 Award 2012". The Microscopy Today 2014 Innovation Award coincides with Leica Microsystems' celebration of 10 years of Leica Super-Resolution Innovation.

Microscopy Today 2014 Innovation Award for Leica Microsystems' Super-Resolution System Leica SR GSD 3D: 3D-enabled GSDIM/dSTORM-based Microscope System Wins Again

Wetzlar, Germany | Posted on August 6th, 2014

"We are proud to be honored with the Microscopy Today 2014 Innovation Award," says Dr. Peter Laskey, Product Manager at Leica Microsystems. "It proves what a significant enhancement the 3D functionality actually is for researchers. The system enables scientists to study cellular structures in near-natural conditions that are three-dimensional by nature. As the system is easy to use and works with common fluorescent dyes, multi-channel, three-dimensional GSDIM/dSTORM images are available within a few minutes."

The capability of acquiring three-dimensional super-resolution images was introduced in 2013, allowing researchers to achieve an axial resolution of 50 nm and a lateral resolution of 20 nm. The new ability offers a huge advantage to cell biologists studying the organization and behavior of sub-cellular structures beyond the diffraction limit in 3D to advance their research. Many of these structures of interest fall far below the resolving abilities of conventional microscope systems, thereby imposing a fundamental limit on the information that can be collected. Super-resolution microscopes reveal previously invisible details with up to 10x greater resolution. The Leica SR GSD, predecessor to the Leica SR GSD 3D, improved resolution in the x/y planes, but offered no additional resolving power in z. The Leica SR GSD 3D overcomes this obstacle by using an astigmatism-based optical approach to extract additional super-resolution information from specimens. The system can now assign z-coordinates to signals from single molecules, allowing it to precisely map their 3D coordinates.

Currently Leica Microsystems looks back on a decade of experience developing super-resolution microscopy systems. Starting with the Leica TCS 4Pi in 2004, Leica Microsystems continued to pioneer other super-resolution techniques. The confocal solution is based on Stimulated Emission Depletion (STED). The Innovation Award winning widefield system uses a technology known as Ground State Depletion followed by Individual Molecule Return (GSDIM). Both techniques were developed at the Max Planck Institute for Biophysical Chemistry in Göttingen, Germany, by Professor Stefan Hell. Through close collaboration with scientific users, Leica Microsystems made these technologies commercially available, and this year celebrates the 10th anniversary of Super-Resolution Innovation with the slogan "Vive La Résolution!"

####

About Leica Microsystems GmbH
Leica Microsystems is a world leader in microscopes and scientific instruments. Founded as a family business in the nineteenth century, the company's history was marked by unparalleled innovation on its way to becoming a global enterprise. Its historically close cooperation with the scientific community is the key to Leica Microsystems' tradition of innovation, which draws on users' ideas and creates solutions tailored to their requirements. At the global level, Leica Microsystems is organized in three divisions, all of which are among the leaders in their respective fields: the Life Science Division, Industry Division and Medical Division. The company is represented in over 100 countries with six manufacturing facilities in five countries, sales and service organizations in 20 countries, and an international network of dealers. The company is headquartered in Wetzlar, Germany.

For more information, please click here

Contacts:
Anja Schué
Claudia Müller
Ernst Leitz Strasse 17-37
35578 Wetzlar (Germany)
Tel. +49 6441 29-2201 / -2630
Fax +49 6441 29-2211

Copyright © Leica Microsystems GmbH

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Solid state physics: Quantum matter stuck in unrest August 1st, 2015

Self-assembling, biomimetic membranes may aid water filtration August 1st, 2015

Transparent, electrically conductive network of encapsulated silver nanowires: A novel electrode for optoelectronics August 1st, 2015

Kalam: versatility personified August 1st, 2015

Imaging

Take a trip through the brain July 30th, 2015

Publication on Atomic Force Microscopy based nanoscale IR Spectroscopy (AFM-IR) persists as a 2015 top downloaded paper July 29th, 2015

Short wavelength plasmons observed in nanotubes: Berkeley Lab researchers create Ludinger liquid plasmons in metallic SWNTs July 28th, 2015

Reshaping the solar spectrum to turn light to electricity: UC Riverside researchers find a way to use the infrared region of the sun's spectrum to make solar cells more efficient July 27th, 2015

Announcements

Self-assembling, biomimetic membranes may aid water filtration August 1st, 2015

Transparent, electrically conductive network of encapsulated silver nanowires: A novel electrode for optoelectronics August 1st, 2015

Harris & Harris Group Portfolio Company, HZO, Announces Partnerships with Dell and Motorola August 1st, 2015

Advances and Applications in Biosensing, Sensor Power, and Sensor R&D to be Covered at Sensors Global Summit August 1st, 2015

Tools

Heating and cooling with light leads to ultrafast DNA diagnostics July 31st, 2015

Take a trip through the brain July 30th, 2015

Publication on Atomic Force Microscopy based nanoscale IR Spectroscopy (AFM-IR) persists as a 2015 top downloaded paper July 29th, 2015

Nanometrics Announces Upcoming Investor Events July 28th, 2015

Grants/Awards/Scholarships/Gifts/Contests/Honors/Records

Heating and cooling with light leads to ultrafast DNA diagnostics July 31st, 2015

Springer and Tsinghua University Press present the second Nano Research Award: Paul Alivisatos of the University of California Berkeley receives the honor for outstanding contributions in nanoscience July 30th, 2015

European Technology Platform for Nanomedicine and ENATRANS European Consortium Launch the 2nd edition of the Nanomedicine Award: The Award to be presented at BIO-Europe conference in Munich, November 2015 July 30th, 2015

Publication on Atomic Force Microscopy based nanoscale IR Spectroscopy (AFM-IR) persists as a 2015 top downloaded paper July 29th, 2015

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project