Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > Newly-Produced Nanocarriers Able to Carry Multiple Drugs Concurrently

Abstract:
Iranian researchers from Tabriz University of Medical Sciences and Treatment Services produced a new type of nanocarriers that are able to deliver two anticancer drugs to cancer cells simultaneously.

Newly-Produced Nanocarriers Able to Carry Multiple Drugs Concurrently

Tehran, Iran | Posted on June 17th, 2014

The nanocarriers have been designed in a way that they release the drug only at controlled pH value and temperature. The research was conducted in a bid to achieve nanostructured intelligent drug delivery systems.

According to Dr. Roya Salehi Qrehvarn, one of the researchers, contrary to the present studies on the delivery of only one anticancer drug at one time, the new nanocarrier carries and releases two anticancer drugs with less amount of drug but more effectiveness. This characteristic reduces the toxicity caused due to the consumption of anticancer drugs, which many of patients have to deal with. In addition, cancer cells do not become resistant to the drugs when the new mechanism is used.

In the production process of the nanocarrier, a new cationic ionic liquid that responds to a few triggers was produced through polymerization method firstly, and then it was attached to silicon nanoparticles and it was modified. Next, the nanoparticles were simultaneously attached to two anticancer drugs of doxorubicin (DOX) and methotrexate (MTX) through electrostatic interactions. HPLC-UV test was used to study the simultaneous release of the drugs.

The nanocarrier did not show any sign of toxicity on cell lines even after 72 hours. However, the fatal effect of nanocarrier containing two anticancer drugs against the medical formulation of lung and breast cancer cells is very noticeable. The nanostructured drug delivery system has been tested in the treatment of rats that suffered from cancer. Results showed the gradual treatment of the rats in a desirable manner.

Results of the research have been published in Journal of Drug Targeting, vol. 22, issue 4, January 2014, pp. 327-342.

####

For more information, please click here

Copyright © Fars News Agency

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Nano-supercapacitors for electric cars July 25th, 2014

New imaging agent provides better picture of the gut July 25th, 2014

Breakthrough laser experiment reveals liquid-like motion of atoms in an ultra-cold cluster: University of Leicester research team unlocks insights into creation of new nano-materials July 25th, 2014

Scientists Test Nanoparticle "Alarm Clock" to Awaken Immune Systems Put to Sleep by Cancer July 25th, 2014

Nanomedicine

New imaging agent provides better picture of the gut July 25th, 2014

Scientists Test Nanoparticle "Alarm Clock" to Awaken Immune Systems Put to Sleep by Cancer July 25th, 2014

Researchers create vaccine for dust-mite allergies Main Page Content: Vaccine reduced lung inflammation to allergens in lab and animal tests July 22nd, 2014

NIST shows ultrasonically propelled nanorods spin dizzyingly fast July 22nd, 2014

Discoveries

New imaging agent provides better picture of the gut July 25th, 2014

Breakthrough laser experiment reveals liquid-like motion of atoms in an ultra-cold cluster: University of Leicester research team unlocks insights into creation of new nano-materials July 25th, 2014

Scientists Test Nanoparticle "Alarm Clock" to Awaken Immune Systems Put to Sleep by Cancer July 25th, 2014

Iranian Scientists Produce Transparent Nanocomposite Coatings with Longer Lifetime July 24th, 2014

Announcements

Nano-supercapacitors for electric cars July 25th, 2014

New imaging agent provides better picture of the gut July 25th, 2014

Breakthrough laser experiment reveals liquid-like motion of atoms in an ultra-cold cluster: University of Leicester research team unlocks insights into creation of new nano-materials July 25th, 2014

Scientists Test Nanoparticle "Alarm Clock" to Awaken Immune Systems Put to Sleep by Cancer July 25th, 2014

Interviews/Book Reviews/Essays/Reports/Podcasts/Journals

Silicene Labs Announces the Launch of 2D Materials Briefing Book™ and 2D Materials Road-Heat Map™: Contributors Include One of the World's Foremost 2D Materials Scientists July 25th, 2014

New imaging agent provides better picture of the gut July 25th, 2014

Breakthrough laser experiment reveals liquid-like motion of atoms in an ultra-cold cluster: University of Leicester research team unlocks insights into creation of new nano-materials July 25th, 2014

Scientists Test Nanoparticle "Alarm Clock" to Awaken Immune Systems Put to Sleep by Cancer July 25th, 2014

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE