Nanotechnology Now

Our NanoNews Digest Sponsors



Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > Rate, Accuracy of Hepatitis B Virus Detection Increased Using Nano-Based Immunosensor

Abstract:
Researchers from the University of Tehran succeeded in designing and producing an immunosensor based on nanotechnology to increase the rate and accuracy of the detection of hepatitis B virus existing in patients' blood serum.

Rate, Accuracy of Hepatitis B Virus Detection Increased Using Nano-Based Immunosensor

Tehran, Iran | Posted on May 26th, 2014

In this research, gold nanoparticles were used to increase the sensitivity of the immunosensor. The sensor is able to detect at least 10 ng/mL of hepatitis B surface antigen.

Results of the research can be used in the production of immunosensors with high quality for the detection of various types of viruses, and the sensors can be used in diagnosis tests in hospitals.

The immunosensor was produced in three phases. At first, the second type antigen was connected to gold nanoparticles. Then, gold nanoparticles were coated by an insulating molecule layer (mercapto alkyl ended to carboxylic acid) through self-arrangement method. Afterwards, carboxylic acid functional groups were chemically activated to connect the antigen to the nanoparticles. The antigen connected to gold nanoparticles and stabilized on the initial antigen formed complex on gold electrodes, and changed the capacity of the capacitor.

Gold nanoparticles were used in this research to increase the sensitivity of the immunosensor, and the secondary antigen was stabilized on the surface of gold nanoparticles.

Due to the large size of the nanoparticles, the secondary antigen connected to gold nanoparticles creates noticeable changes in dielectric layer and the capacity of the capacitor. In addition to increasing the sensitivity, it decreases the detection limit to about 10 ng/mL.

Results of the research have been published in Analytical Methods, vol. 5, issue 17, January 2013, pp. 4448-4453.

####

For more information, please click here

Copyright © Fars News Agency

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Iranian Researchers Synthesize Stable Ceramic Nanopowders at Room Temperature September 20th, 2014

Arrowhead to Present at BioCentury's NewsMakers in the Biotech Industry Conference September 19th, 2014

SouthWest NanoTechnologies (SWeNT) Receives NIST Small Business Innovation Research (SBIR) Phase 1 Award to Produce Greater than 99% Semiconducting Single-Wall Carbon Nanotubes September 19th, 2014

Toward optical chips: A promising light source for optoelectronic chips can be tuned to different frequencies September 19th, 2014

Nanomedicine

Arrowhead to Present at BioCentury's NewsMakers in the Biotech Industry Conference September 19th, 2014

The Pocket Project will develop a low-cost and accurate point-of-care test to diagnose Tuberculosis: ICN2 holds a follow-up meeting of the Project on September 18th - 19th September 18th, 2014

New non-invasive technique could revolutionize the imaging of metastatic cancer September 17th, 2014

Recruiting bacteria to be technology innovation partners: September 17th, 2014

Discoveries

Iranian Scientists Separate Zinc Ion at Low Concentrations September 20th, 2014

Iranian Researchers Synthesize Stable Ceramic Nanopowders at Room Temperature September 20th, 2014

Toward optical chips: A promising light source for optoelectronic chips can be tuned to different frequencies September 19th, 2014

New research points to graphene as a flexible, low-cost touchscreen solution September 19th, 2014

Announcements

Iranian Scientists Separate Zinc Ion at Low Concentrations September 20th, 2014

Arrowhead to Present at BioCentury's NewsMakers in the Biotech Industry Conference September 19th, 2014

SouthWest NanoTechnologies (SWeNT) Receives NIST Small Business Innovation Research (SBIR) Phase 1 Award to Produce Greater than 99% Semiconducting Single-Wall Carbon Nanotubes September 19th, 2014

Toward optical chips: A promising light source for optoelectronic chips can be tuned to different frequencies September 19th, 2014

Interviews/Book Reviews/Essays/Reports/Podcasts/Journals

Iranian Scientists Separate Zinc Ion at Low Concentrations September 20th, 2014

Iranian Researchers Synthesize Stable Ceramic Nanopowders at Room Temperature September 20th, 2014

Toward optical chips: A promising light source for optoelectronic chips can be tuned to different frequencies September 19th, 2014

New research points to graphene as a flexible, low-cost touchscreen solution September 19th, 2014

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE