Nanotechnology Now

Our NanoNews Digest Sponsors



Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > Rate, Accuracy of Hepatitis B Virus Detection Increased Using Nano-Based Immunosensor

Abstract:
Researchers from the University of Tehran succeeded in designing and producing an immunosensor based on nanotechnology to increase the rate and accuracy of the detection of hepatitis B virus existing in patients' blood serum.

Rate, Accuracy of Hepatitis B Virus Detection Increased Using Nano-Based Immunosensor

Tehran, Iran | Posted on May 26th, 2014

In this research, gold nanoparticles were used to increase the sensitivity of the immunosensor. The sensor is able to detect at least 10 ng/mL of hepatitis B surface antigen.

Results of the research can be used in the production of immunosensors with high quality for the detection of various types of viruses, and the sensors can be used in diagnosis tests in hospitals.

The immunosensor was produced in three phases. At first, the second type antigen was connected to gold nanoparticles. Then, gold nanoparticles were coated by an insulating molecule layer (mercapto alkyl ended to carboxylic acid) through self-arrangement method. Afterwards, carboxylic acid functional groups were chemically activated to connect the antigen to the nanoparticles. The antigen connected to gold nanoparticles and stabilized on the initial antigen formed complex on gold electrodes, and changed the capacity of the capacitor.

Gold nanoparticles were used in this research to increase the sensitivity of the immunosensor, and the secondary antigen was stabilized on the surface of gold nanoparticles.

Due to the large size of the nanoparticles, the secondary antigen connected to gold nanoparticles creates noticeable changes in dielectric layer and the capacity of the capacitor. In addition to increasing the sensitivity, it decreases the detection limit to about 10 ng/mL.

Results of the research have been published in Analytical Methods, vol. 5, issue 17, January 2013, pp. 4448-4453.

####

For more information, please click here

Copyright © Fars News Agency

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

New research project supports internationalisation in nano-research: Launch of new “Baltic Sea Network” November 22nd, 2014

3rd Iran-Proposed Nano Standard Approved by International Standard Organization November 22nd, 2014

NMTI announces breakthrough solutions for HAMR nanoantenna for next-generation ultra-high density magnetic storage November 21st, 2014

Canatu Launches CNB In-Mold Film for Transparent Touch on 3D Surfaces –in Cars, Household Appliances, Wearables, Portables November 20th, 2014

Nanomedicine

New research project supports internationalisation in nano-research: Launch of new “Baltic Sea Network” November 22nd, 2014

Quantum mechanical calculations reveal the hidden states of enzyme active sites November 20th, 2014

Silver Nanoparticles Produced in Iran from Forest Plants Extract November 20th, 2014

Tokyo Institute of Technology research: Protein-engineered cages aid studies of cell functions November 19th, 2014

Discoveries

NMTI announces breakthrough solutions for HAMR nanoantenna for next-generation ultra-high density magnetic storage November 21st, 2014

UO-industry collaboration points to improved nanomaterials: University of Oregon microscope puts spotlight on the surface structure of quantum dots for designing new solar devices November 20th, 2014

Silver Nanoparticles Produced in Iran from Forest Plants Extract November 20th, 2014

Nano Sorbents Able to Remove Pollutions Caused by Oil Derivatives November 20th, 2014

Announcements

New research project supports internationalisation in nano-research: Launch of new “Baltic Sea Network” November 22nd, 2014

3rd Iran-Proposed Nano Standard Approved by International Standard Organization November 22nd, 2014

NMTI announces breakthrough solutions for HAMR nanoantenna for next-generation ultra-high density magnetic storage November 21st, 2014

Nano Sorbents Able to Remove Pollutions Caused by Oil Derivatives November 20th, 2014

Interviews/Book Reviews/Essays/Reports/Podcasts/Journals/White papers

NMTI announces breakthrough solutions for HAMR nanoantenna for next-generation ultra-high density magnetic storage November 21st, 2014

Quantum mechanical calculations reveal the hidden states of enzyme active sites November 20th, 2014

UO-industry collaboration points to improved nanomaterials: University of Oregon microscope puts spotlight on the surface structure of quantum dots for designing new solar devices November 20th, 2014

Silver Nanoparticles Produced in Iran from Forest Plants Extract November 20th, 2014

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More












ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE