Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > Scientists Introduce New Contrast Agent to Detect Ovarian Cancer Cells

Abstract:
New SPION-C595 contrast agent was introduced, designed and produced by Iranian researchers to detect and take images from ovarian cancer cells to be used in targeted magnetic resonance molecular imaging.

Scientists Introduce New Contrast Agent to Detect Ovarian Cancer Cells

Tehran, Iran | Posted on February 12th, 2014

Dr. Daryoush Shahbazi Gahrouyee, professor of medical physics in Isfahan University of Medical Sciences, explained about the research. "Magnetic nanoprobe that is super paramagnetic iron oxide nanoparticles (SPIONs-C959) bonded with folic acid was produced firstly. In this research, the new contrast agent (SPIONs-C595) was introduced, designed and produced to detect and take images from ovarian cancer cells to be used in targeted magnetic resonance molecular imaging."

"The compound was firstly prepared and then, toxicity tests and quality control tests were carried out, including studying hydrodynamic size changes of particles, magnetic properties and resting time. The performance of the designed nanoprobe was studied in its ability to be attached to cancerous cells under in-vivo and in-vitro conditions with taking MRI images, and the changes in the strength of imaging signal were investigated too. The produced compound had desirable stability and biocompatibility at in-vitro condition, to the extent that in the majority of concentrations and test times, the life duration of cells was reported to be higher than 80%," he said.

Resting time tests and concentration of iron at the level of ovarian cancer cells and MR images taken after the incubation of the cells with the synthesized nanoprobe and the commercial nanoparticles used in this study indicated much higher tendency of the attachment of the produced compound with the cellular level with high expression of C595 antigen. Although the performance of the nanoprobe was less than what expected under in-vitro conditions, in-vivo experiments confirm the higher tendency of the product for staying in tumor tissue in comparison with the commercial nanoparticles used in the research.

Results of the research have been published in details in The Scientific World Journal, 2013.

####

For more information, please click here

Copyright © Fars News Agency

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Chains of nanogold – forged with atomic precision September 23rd, 2016

Tattoo therapy could ease chronic disease: Rice-made nanoparticles tested at Baylor College of Medicine may help control autoimmune diseases September 23rd, 2016

Nanotech Grants Options September 22nd, 2016

Coffee-infused foam removes lead from contaminated water September 21st, 2016

As You Sow’s Shareholder Inquiry on Nanomaterials Fought by Walgreens: Shareholder Proposal Addresses Recent Laboratory Tests Finding Harmful Nanomaterials in Walgreens’ Store Brand Infant Formula September 21st, 2016

Imaging

Oxford Instruments is ‘Bringing the Nanoworld Together’ in India once again - 22 - 23 November 2016 | IISc Bangalore September 21st, 2016

Bruker Introduces Complete Commercial AFM-Based SECM Solution: PeakForce SECM Mode Enables Previously Unobtainable Electrochemical Information September 20th, 2016

Discoveries

Chains of nanogold – forged with atomic precision September 23rd, 2016

Tattoo therapy could ease chronic disease: Rice-made nanoparticles tested at Baylor College of Medicine may help control autoimmune diseases September 23rd, 2016

Speedy bacteria detector could help prevent foodborne illnesses September 21st, 2016

Coffee-infused foam removes lead from contaminated water September 21st, 2016

Announcements

Chains of nanogold – forged with atomic precision September 23rd, 2016

Tattoo therapy could ease chronic disease: Rice-made nanoparticles tested at Baylor College of Medicine may help control autoimmune diseases September 23rd, 2016

Nanotech Grants Options September 22nd, 2016

Coffee-infused foam removes lead from contaminated water September 21st, 2016

Interviews/Book Reviews/Essays/Reports/Podcasts/Journals/White papers

Chains of nanogold – forged with atomic precision September 23rd, 2016

Tattoo therapy could ease chronic disease: Rice-made nanoparticles tested at Baylor College of Medicine may help control autoimmune diseases September 23rd, 2016

Speedy bacteria detector could help prevent foodborne illnesses September 21st, 2016

Coffee-infused foam removes lead from contaminated water September 21st, 2016

Tools

Oxford Instruments is ‘Bringing the Nanoworld Together’ in India once again - 22 - 23 November 2016 | IISc Bangalore September 21st, 2016

Bruker Introduces Complete Commercial AFM-Based SECM Solution: PeakForce SECM Mode Enables Previously Unobtainable Electrochemical Information September 20th, 2016

Oxford Instruments Asylum Research Announces New SurfRider Econo Board Probes for Routine AFM Measurements September 19th, 2016

Electron beam microscope directly writes nanoscale features in liquid with metal ink September 16th, 2016

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







Car Brands
Buy website traffic