Nanotechnology Now







Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Scientists Introduce New Contrast Agent to Detect Ovarian Cancer Cells

Abstract:
New SPION-C595 contrast agent was introduced, designed and produced by Iranian researchers to detect and take images from ovarian cancer cells to be used in targeted magnetic resonance molecular imaging.

Scientists Introduce New Contrast Agent to Detect Ovarian Cancer Cells

Tehran, Iran | Posted on February 12th, 2014

Dr. Daryoush Shahbazi Gahrouyee, professor of medical physics in Isfahan University of Medical Sciences, explained about the research. "Magnetic nanoprobe that is super paramagnetic iron oxide nanoparticles (SPIONs-C959) bonded with folic acid was produced firstly. In this research, the new contrast agent (SPIONs-C595) was introduced, designed and produced to detect and take images from ovarian cancer cells to be used in targeted magnetic resonance molecular imaging."

"The compound was firstly prepared and then, toxicity tests and quality control tests were carried out, including studying hydrodynamic size changes of particles, magnetic properties and resting time. The performance of the designed nanoprobe was studied in its ability to be attached to cancerous cells under in-vivo and in-vitro conditions with taking MRI images, and the changes in the strength of imaging signal were investigated too. The produced compound had desirable stability and biocompatibility at in-vitro condition, to the extent that in the majority of concentrations and test times, the life duration of cells was reported to be higher than 80%," he said.

Resting time tests and concentration of iron at the level of ovarian cancer cells and MR images taken after the incubation of the cells with the synthesized nanoprobe and the commercial nanoparticles used in this study indicated much higher tendency of the attachment of the produced compound with the cellular level with high expression of C595 antigen. Although the performance of the nanoprobe was less than what expected under in-vitro conditions, in-vivo experiments confirm the higher tendency of the product for staying in tumor tissue in comparison with the commercial nanoparticles used in the research.

Results of the research have been published in details in The Scientific World Journal, 2013.

####

For more information, please click here

Copyright © Fars News Agency

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

Imaging

Visualizing interacting electrons in a molecule: Scientists at Aalto University and the University of Zurich have succeeded in directly imaging how electrons interact within a single molecule January 26th, 2015

News and information

Nanoparticles Increase Durability of Concrete Decorations in Cold Areas January 26th, 2015

Iranian Researchers Boost Solar Cells Efficiency Using Anti-Aggregates January 26th, 2015

Detection of Heavy Metals in Samples with Naked Eye January 26th, 2015

Engineering self-assembling amyloid fibers January 26th, 2015

Discoveries

Visualizing interacting electrons in a molecule: Scientists at Aalto University and the University of Zurich have succeeded in directly imaging how electrons interact within a single molecule January 26th, 2015

Electronic circuits with reconfigurable pathways closer to reality January 26th, 2015

Nanoparticles Increase Durability of Concrete Decorations in Cold Areas January 26th, 2015

Iranian Researchers Boost Solar Cells Efficiency Using Anti-Aggregates January 26th, 2015

Announcements

Nanoparticles Increase Durability of Concrete Decorations in Cold Areas January 26th, 2015

Iranian Researchers Boost Solar Cells Efficiency Using Anti-Aggregates January 26th, 2015

Detection of Heavy Metals in Samples with Naked Eye January 26th, 2015

Engineering self-assembling amyloid fibers January 26th, 2015

Interviews/Book Reviews/Essays/Reports/Podcasts/Journals/White papers

Visualizing interacting electrons in a molecule: Scientists at Aalto University and the University of Zurich have succeeded in directly imaging how electrons interact within a single molecule January 26th, 2015

Electronic circuits with reconfigurable pathways closer to reality January 26th, 2015

Fullerex launches 2015 edition of the Bulk Graphene Pricing Report January 26th, 2015

Nanoparticles Increase Durability of Concrete Decorations in Cold Areas January 26th, 2015

Tools

Visualizing interacting electrons in a molecule: Scientists at Aalto University and the University of Zurich have succeeded in directly imaging how electrons interact within a single molecule January 26th, 2015

Graphene brings quantum effects to electronic circuits January 22nd, 2015

EnvisioNano: An image contest hosted by the National Nanotechnology Initiative (NNI) January 22nd, 2015

New Molecular Beam Epitaxy deposition equipment at the ICN2 January 22nd, 2015

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More










ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2015 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE