Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > Production of Hyperbranched Drug-Carrying Polymers from Citric Acid Monomers in Iran

Abstract:
Iranian researchers from Payam-e Nour University of Tabriz in association with researchers from Lorestan University succeeded in the production of biodegradable hyperbranched polymers that are compatible with human body temperature.

Production of Hyperbranched Drug-Carrying Polymers from Citric Acid Monomers in Iran

Tehran, Iran | Posted on January 11th, 2014

The polymers are made of citric acid and glycerol monomers through dense polymerization method, and they can be used as drug-carrying nanoparticles in medical purposes, specially in cancer treatment.

Since citric acid decomposes at its melting point, the polymerization of this monomer is not possible for the preparation of polymers and copolymers. Three various types of hyperbranched polymers were synthesized in this research with different ratios of citric acid and glycerol under the same conditions of temperature and time. The polymer is compatible with biological media, and it has numerous internal voids that enable it to carry drug. The presence of functional groups on the surface of the polymer results in the release of the drug to the target. The abovementioned polymers can have desirable application in the place of biological molecules.

The hyperbranched polymers can be easily synthesized with very high molecular weight by changing two important parameters of reaction time and ratio of the monomer. The polymers are able to pass through cell membrane. Similar to dendrimers, the polymers have many functional groups and internal voids, so they are considered appropriate carriers of various medical molecules such as cancer treatment medicine, including cisplatin, through physical (capsulation) or chemical (coupling) methods.

Results of the research showed that the production of hyperbranched polymer was cost-effective. Moreover, the dosage of anticancer drug capsulated with hyperbranched polymer was halved in comparison with that in free anticancer drug. Therefore, the side-effects caused by the anticancer drug reduced on healthy cells.

The latest results of the research have been published in Journal of Applied Polymer Science, vol. 129, issue 6, 15 September 2013, pp. 3665-3671.

####

For more information, please click here

Copyright © Fars News Agency

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Iran to Hold 3rd Int'l Engineering Materials, Metallurgy Conference October 25th, 2014

Haydale Secures Exclusive Development and Supply Agreement with Tantec A/S: New reactors to be built and commissioned by Tantec A/S represent another step forward towards the commercialisation of graphene October 24th, 2014

QuantumWise guides the semiconductor industry towards the atomic scale October 24th, 2014

SUNY Polytechnic Institute Invites the Public to Attend its Popular Statewide 'NANOvember' Series of Outreach and Educational Events October 23rd, 2014

Nanomedicine

NYU Researchers Break Nano Barrier to Engineer the First Protein Microfiber October 23rd, 2014

Iranian Scientists Apply Nanotechnology to Produce Surgery Suture October 23rd, 2014

RF Heating of Magnetic Nanoparticles Improves the Thawing of Cryopreserved Biomaterials October 23rd, 2014

Sopping up proteins with thermosponges: Researchers develop novel nanoparticle platform that proves effective in delivering protein-based drugs October 22nd, 2014

Discoveries

QuantumWise guides the semiconductor industry towards the atomic scale October 24th, 2014

Iranian, Malaysian Scientists Study Nanophotocatalysts for Water Purification October 23rd, 2014

Nanoparticle technology triples the production of biogas October 23rd, 2014

Strengthening thin-film bonds with ultrafast data collection October 23rd, 2014

Announcements

Iran to Hold 3rd Int'l Engineering Materials, Metallurgy Conference October 25th, 2014

Haydale Secures Exclusive Development and Supply Agreement with Tantec A/S: New reactors to be built and commissioned by Tantec A/S represent another step forward towards the commercialisation of graphene October 24th, 2014

QuantumWise guides the semiconductor industry towards the atomic scale October 24th, 2014

Strengthening thin-film bonds with ultrafast data collection October 23rd, 2014

Interviews/Book Reviews/Essays/Reports/Podcasts/Journals

NYU Researchers Break Nano Barrier to Engineer the First Protein Microfiber October 23rd, 2014

Iranian Scientists Apply Nanotechnology to Produce Surgery Suture October 23rd, 2014

Iranian, Malaysian Scientists Study Nanophotocatalysts for Water Purification October 23rd, 2014

Strengthening thin-film bonds with ultrafast data collection October 23rd, 2014

NanoNews-Digest
The latest news from around the world, FREE





  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE