Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > Production of Hyperbranched Drug-Carrying Polymers from Citric Acid Monomers in Iran

Abstract:
Iranian researchers from Payam-e Nour University of Tabriz in association with researchers from Lorestan University succeeded in the production of biodegradable hyperbranched polymers that are compatible with human body temperature.

Production of Hyperbranched Drug-Carrying Polymers from Citric Acid Monomers in Iran

Tehran, Iran | Posted on January 11th, 2014

The polymers are made of citric acid and glycerol monomers through dense polymerization method, and they can be used as drug-carrying nanoparticles in medical purposes, specially in cancer treatment.

Since citric acid decomposes at its melting point, the polymerization of this monomer is not possible for the preparation of polymers and copolymers. Three various types of hyperbranched polymers were synthesized in this research with different ratios of citric acid and glycerol under the same conditions of temperature and time. The polymer is compatible with biological media, and it has numerous internal voids that enable it to carry drug. The presence of functional groups on the surface of the polymer results in the release of the drug to the target. The abovementioned polymers can have desirable application in the place of biological molecules.

The hyperbranched polymers can be easily synthesized with very high molecular weight by changing two important parameters of reaction time and ratio of the monomer. The polymers are able to pass through cell membrane. Similar to dendrimers, the polymers have many functional groups and internal voids, so they are considered appropriate carriers of various medical molecules such as cancer treatment medicine, including cisplatin, through physical (capsulation) or chemical (coupling) methods.

Results of the research showed that the production of hyperbranched polymer was cost-effective. Moreover, the dosage of anticancer drug capsulated with hyperbranched polymer was halved in comparison with that in free anticancer drug. Therefore, the side-effects caused by the anticancer drug reduced on healthy cells.

The latest results of the research have been published in Journal of Applied Polymer Science, vol. 129, issue 6, 15 September 2013, pp. 3665-3671.

####

For more information, please click here

Copyright © Fars News Agency

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Imec Reports Four Percent Growth for 2013 Fiscal Year End —Continues to Accelerate Innovation Through Global Collaborations and Technological Breakthroughs in Nanoelectronics— April 24th, 2014

Multicapacity Microreactor for Catalyst Characterisation April 24th, 2014

Making graphene work for real-world devices: Fundamental research in phonon scattering helps researchers design graphene materials for applications April 24th, 2014

Return on investment for kit and promotion materials April 24th, 2014

Nanomedicine

Return on investment for kit and promotion materials April 24th, 2014

University of Tehran Researchers Invent Non-Enzyme Sensor to Detect Blood Sugar April 23rd, 2014

Gold nanoparticles help target, quantify breast cancer gene segments in a living cell April 23rd, 2014

QuantuMDx announce prototype handheld lab for 15 minute malaria diagnosis and drug resistance testing April 23rd, 2014

Discoveries

Making graphene work for real-world devices: Fundamental research in phonon scattering helps researchers design graphene materials for applications April 24th, 2014

Return on investment for kit and promotion materials April 24th, 2014

Protecting olive oil from counterfeiters April 24th, 2014

Gold nanoparticles help target, quantify breast cancer gene segments in a living cell April 23rd, 2014

Announcements

Imec Reports Four Percent Growth for 2013 Fiscal Year End —Continues to Accelerate Innovation Through Global Collaborations and Technological Breakthroughs in Nanoelectronics— April 24th, 2014

Multicapacity Microreactor for Catalyst Characterisation April 24th, 2014

Making graphene work for real-world devices: Fundamental research in phonon scattering helps researchers design graphene materials for applications April 24th, 2014

Return on investment for kit and promotion materials April 24th, 2014

Interviews/Book Reviews/Essays/Reports/Podcasts/Journals

Making graphene work for real-world devices: Fundamental research in phonon scattering helps researchers design graphene materials for applications April 24th, 2014

Return on investment for kit and promotion materials April 24th, 2014

Protecting olive oil from counterfeiters April 24th, 2014

High-Performance, Low-Cost Ultracapacitors Built with Graphene and Carbon Nanotubes: Future devices based on technology could bridge gap between batteries and conventional capacitors in portable electronics and hybrid electric vehicles April 23rd, 2014

NanoNews-Digest
The latest news from around the world, FREE







  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE