Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > Iron Oxide Nanoparticles Help Investigation of Cognitive Diseases

Abstract:
Iranian researchers from Islamic Azad University, Tehran Branch, in association with researchers from Institute of Biochemistry & Biophysics (IBB) of University of Tehran carried out in vitro an investigation into the changes in the structure of proteins inside brain cells and the interactions of the proteins using iron oxide nanoparticles.

Iron Oxide Nanoparticles Help Investigation of Cognitive Diseases

Tehran, Iran | Posted on November 21st, 2013

The progress of cognitive diseases that do not have any known definite treatment can be prevented if a treatment method is designed and optimized for cognitive diseases such as Alzheimer's-based on controlling metabolism processes of iron oxide in brain cells.

The research showed that microtubules can create magnetic field around themselves due to their dynamic properties and electrical charge. Therefore, they can play role in the transference of electrical signals in brain cells (neurons). It can be said that the protein plays an important role in the transference and probably in saving date in the brain. The malfunction in the performance of microtubules is one of the reasons for the appearance of cognitive diseases such as Alzheimer's.

Iron oxide nanoparticles were firstly produced in this research. Then, microtubule protein was extracted from the brain of a newly-died sheep, and its activity was studied through turbidimetry method. Next, the researchers studied the interaction between nanoparticles and microtubule and tau protein (a protein which is effective in the structural and functional stability of microtubules).

Results of the research showed that iron oxide magnetic nanoparticles and microtubules existing in the neurons can have magnetic interactions with each other, which is essential for the transference and conservation of brain data. However, if the nanoparticles are accumulated in the brain, which can be caused due to the malfunction of iron metabolism in brain cells and due to the improper conservation of iron in a protein called ferritin, the abovementioned interaction may be damaged, and nanoparticles connect with microtubules and tau protein, which results in the instability of microtubular polymers.

A part of the results of the research have been published in February 2013 in Journal of Biological Inorganic Chemistry, vol. 18, issue 3, pp. 357-369.

####

For more information, please click here

Copyright © Fars News Agency

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

NanoSafe, Inc. announces the addition of the Labconco Protector® Glove Box to its NanoSafe Tested™ registry April 23rd, 2014

Study finds long-term survival of human neural stem cells transplanted into primate brain April 23rd, 2014

High-Performance, Low-Cost Ultracapacitors Built with Graphene and Carbon Nanotubes: Future devices based on technology could bridge gap between batteries and conventional capacitors in portable electronics and hybrid electric vehicles April 23rd, 2014

Guo Lab Shows Potential of RNA as Heat-resistant Polymer Material for Nanoarchitectures April 23rd, 2014

Nanomedicine

Study finds long-term survival of human neural stem cells transplanted into primate brain April 23rd, 2014

Cloaked DNA nanodevices survive pilot mission: Successful foray opens door to virus-like DNA nanodevices that could diagnose diseased tissues and manufacture drugs to treat them April 22nd, 2014

Berkeley Lab Researchers Demonstrate First Size-based Chromatography Technique for the Study of Living Cells April 22nd, 2014

Amino-functionalized carbon nanotubes act as a carrier for nerve growth factor April 21st, 2014

Discoveries

Study finds long-term survival of human neural stem cells transplanted into primate brain April 23rd, 2014

High-Performance, Low-Cost Ultracapacitors Built with Graphene and Carbon Nanotubes: Future devices based on technology could bridge gap between batteries and conventional capacitors in portable electronics and hybrid electric vehicles April 23rd, 2014

Guo Lab Shows Potential of RNA as Heat-resistant Polymer Material for Nanoarchitectures April 23rd, 2014

Berkeley Lab Researchers Demonstrate First Size-based Chromatography Technique for the Study of Living Cells April 22nd, 2014

Announcements

NanoSafe, Inc. announces the addition of the Labconco Protector® Glove Box to its NanoSafe Tested™ registry April 23rd, 2014

Study finds long-term survival of human neural stem cells transplanted into primate brain April 23rd, 2014

High-Performance, Low-Cost Ultracapacitors Built with Graphene and Carbon Nanotubes: Future devices based on technology could bridge gap between batteries and conventional capacitors in portable electronics and hybrid electric vehicles April 23rd, 2014

Guo Lab Shows Potential of RNA as Heat-resistant Polymer Material for Nanoarchitectures April 23rd, 2014

Interviews/Book Reviews/Essays/Reports/Podcasts/Journals

Study finds long-term survival of human neural stem cells transplanted into primate brain April 23rd, 2014

High-Performance, Low-Cost Ultracapacitors Built with Graphene and Carbon Nanotubes: Future devices based on technology could bridge gap between batteries and conventional capacitors in portable electronics and hybrid electric vehicles April 23rd, 2014

Guo Lab Shows Potential of RNA as Heat-resistant Polymer Material for Nanoarchitectures April 23rd, 2014

Berkeley Lab Researchers Demonstrate First Size-based Chromatography Technique for the Study of Living Cells April 22nd, 2014

Research partnerships

University of Waterloo Visits China to Strengthen Bonds With Research Partners April 21st, 2014

Novel stapled peptide nanoparticle combination prevents RSV infection, study finds April 17th, 2014

Scientists Capture Ultrafast Snapshots of Light-Driven Superconductivity: X-rays reveal how rapidly vanishing 'charge stripes' may be behind laser-induced high-temperature superconductivity April 16th, 2014

Scalable CVD process for making 2-D molybdenum diselenide: Rice, NTU scientists unveil CVD production for coveted 2-D semiconductor April 8th, 2014

NanoNews-Digest
The latest news from around the world, FREE







  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE