Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > Iron Oxide Nanoparticles Help Investigation of Cognitive Diseases

Abstract:
Iranian researchers from Islamic Azad University, Tehran Branch, in association with researchers from Institute of Biochemistry & Biophysics (IBB) of University of Tehran carried out in vitro an investigation into the changes in the structure of proteins inside brain cells and the interactions of the proteins using iron oxide nanoparticles.

Iron Oxide Nanoparticles Help Investigation of Cognitive Diseases

Tehran, Iran | Posted on November 21st, 2013

The progress of cognitive diseases that do not have any known definite treatment can be prevented if a treatment method is designed and optimized for cognitive diseases such as Alzheimer's-based on controlling metabolism processes of iron oxide in brain cells.

The research showed that microtubules can create magnetic field around themselves due to their dynamic properties and electrical charge. Therefore, they can play role in the transference of electrical signals in brain cells (neurons). It can be said that the protein plays an important role in the transference and probably in saving date in the brain. The malfunction in the performance of microtubules is one of the reasons for the appearance of cognitive diseases such as Alzheimer's.

Iron oxide nanoparticles were firstly produced in this research. Then, microtubule protein was extracted from the brain of a newly-died sheep, and its activity was studied through turbidimetry method. Next, the researchers studied the interaction between nanoparticles and microtubule and tau protein (a protein which is effective in the structural and functional stability of microtubules).

Results of the research showed that iron oxide magnetic nanoparticles and microtubules existing in the neurons can have magnetic interactions with each other, which is essential for the transference and conservation of brain data. However, if the nanoparticles are accumulated in the brain, which can be caused due to the malfunction of iron metabolism in brain cells and due to the improper conservation of iron in a protein called ferritin, the abovementioned interaction may be damaged, and nanoparticles connect with microtubules and tau protein, which results in the instability of microtubular polymers.

A part of the results of the research have been published in February 2013 in Journal of Biological Inorganic Chemistry, vol. 18, issue 3, pp. 357-369.

####

For more information, please click here

Copyright © Fars News Agency

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Industrial Nanotech, Inc. to Publish PCAOB Audited Financials July 31st, 2014

Nanostructured metal-oxide catalyst efficiently converts CO2 to methanol: Highly reactive sites at interface of 2 nanoscale components could help overcome hurdle of using CO2 as a starting point in producing useful products July 31st, 2014

Carnegie Mellon Chemists Create Nanofibers Using Unprecedented New Method July 31st, 2014

Pressure probing potential photoelectronic manufacturing compound July 31st, 2014

Nanomedicine

Arrowhead to Report Fiscal 2014 Third Quarter Financial Results- Conference Call Scheduled for Tuesday, August 12, 2014 - July 31st, 2014

New imaging agent provides better picture of the gut July 30th, 2014

Zenosense, Inc. July 29th, 2014

Optimum inertial design for self-propulsion: A new study investigates the effects of small but finite inertia on the propulsion of micro and nano-scale swimming machines July 29th, 2014

Discoveries

Study finds physical link to strange electronic behavior: Neutron measurements offer new clues about iron-based superconductor July 31st, 2014

Nanostructured metal-oxide catalyst efficiently converts CO2 to methanol: Highly reactive sites at interface of 2 nanoscale components could help overcome hurdle of using CO2 as a starting point in producing useful products July 31st, 2014

Carnegie Mellon Chemists Create Nanofibers Using Unprecedented New Method July 31st, 2014

Pressure probing potential photoelectronic manufacturing compound July 31st, 2014

Announcements

Industrial Nanotech, Inc. to Publish PCAOB Audited Financials July 31st, 2014

Nanostructured metal-oxide catalyst efficiently converts CO2 to methanol: Highly reactive sites at interface of 2 nanoscale components could help overcome hurdle of using CO2 as a starting point in producing useful products July 31st, 2014

Carnegie Mellon Chemists Create Nanofibers Using Unprecedented New Method July 31st, 2014

Pressure probing potential photoelectronic manufacturing compound July 31st, 2014

Interviews/Book Reviews/Essays/Reports/Podcasts/Journals

Carnegie Mellon Chemists Create Nanofibers Using Unprecedented New Method July 31st, 2014

Pressure probing potential photoelectronic manufacturing compound July 31st, 2014

NanoScience: Giants of the Infinitesimal July 31st, 2014

From Narrow to Broad July 30th, 2014

Research partnerships

Study finds physical link to strange electronic behavior: Neutron measurements offer new clues about iron-based superconductor July 31st, 2014

Carnegie Mellon Chemists Create Nanofibers Using Unprecedented New Method July 31st, 2014

New imaging agent provides better picture of the gut July 30th, 2014

Breakthrough laser experiment reveals liquid-like motion of atoms in an ultra-cold cluster: University of Leicester research team unlocks insights into creation of new nano-materials July 25th, 2014

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE