Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Iron Oxide Nanoparticles Help Investigation of Cognitive Diseases

Abstract:
Iranian researchers from Islamic Azad University, Tehran Branch, in association with researchers from Institute of Biochemistry & Biophysics (IBB) of University of Tehran carried out in vitro an investigation into the changes in the structure of proteins inside brain cells and the interactions of the proteins using iron oxide nanoparticles.

Iron Oxide Nanoparticles Help Investigation of Cognitive Diseases

Tehran, Iran | Posted on November 21st, 2013

The progress of cognitive diseases that do not have any known definite treatment can be prevented if a treatment method is designed and optimized for cognitive diseases such as Alzheimer's-based on controlling metabolism processes of iron oxide in brain cells.

The research showed that microtubules can create magnetic field around themselves due to their dynamic properties and electrical charge. Therefore, they can play role in the transference of electrical signals in brain cells (neurons). It can be said that the protein plays an important role in the transference and probably in saving date in the brain. The malfunction in the performance of microtubules is one of the reasons for the appearance of cognitive diseases such as Alzheimer's.

Iron oxide nanoparticles were firstly produced in this research. Then, microtubule protein was extracted from the brain of a newly-died sheep, and its activity was studied through turbidimetry method. Next, the researchers studied the interaction between nanoparticles and microtubule and tau protein (a protein which is effective in the structural and functional stability of microtubules).

Results of the research showed that iron oxide magnetic nanoparticles and microtubules existing in the neurons can have magnetic interactions with each other, which is essential for the transference and conservation of brain data. However, if the nanoparticles are accumulated in the brain, which can be caused due to the malfunction of iron metabolism in brain cells and due to the improper conservation of iron in a protein called ferritin, the abovementioned interaction may be damaged, and nanoparticles connect with microtubules and tau protein, which results in the instability of microtubular polymers.

A part of the results of the research have been published in February 2013 in Journal of Biological Inorganic Chemistry, vol. 18, issue 3, pp. 357-369.

####

For more information, please click here

Copyright © Fars News Agency

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

National Science Foundation Selects SUNY Poly CNSE for Expanded $2.1M Northeast Advanced Technological Education Center: NSF Center Locates to NanoCollege in Support of Flourishing Tech Industry in NYS September 1st, 2015

RUSNANOPRIZE Directorate Announces New Deadline for Nominations Submission September 11, 2015 September 1st, 2015

$200K Awarded to Develop In Vitro Lung Test for Toxicity of Inhaled Nanomaterials: In Vitro Lung Test Designed to Protect Human Health and Replace Animal Testing September 1st, 2015

Hot electrons point the way to perfect light absorption: Physicists study how to achieve perfect absorption of light with the help of rough ultrathin films September 1st, 2015

Nanomedicine

Using DNA origami to build nanodevices of the future September 1st, 2015

Efficiency of Nanodrug Containing Antibiotics in Treatment of Infectious Diseases Evaluated August 31st, 2015

Researchers use DNA 'clews' to shuttle CRISPR-Cas9 gene-editing tool into cells August 30th, 2015

Iranian Scientists Use Artemisia Annua Plant to Produce Breast Cancer Drugs August 29th, 2015

Discoveries

Hot electrons point the way to perfect light absorption: Physicists study how to achieve perfect absorption of light with the help of rough ultrathin films September 1st, 2015

Using DNA origami to build nanodevices of the future September 1st, 2015

Scientists 'squeeze' light one particle at a time: A team of scientists have measured a bizarre effect in quantum physics, in which individual particles of light are said to have been 'squeezed' -- an achievement which at least one textbook had written off as hopeless September 1st, 2015

Using ultrathin sheets to discover new class of wrapped shapes: UMass Amherst materials researchers describe a new regime of wrapped shapes August 31st, 2015

Announcements

$200K Awarded to Develop In Vitro Lung Test for Toxicity of Inhaled Nanomaterials: In Vitro Lung Test Designed to Protect Human Health and Replace Animal Testing September 1st, 2015

Hot electrons point the way to perfect light absorption: Physicists study how to achieve perfect absorption of light with the help of rough ultrathin films September 1st, 2015

Using DNA origami to build nanodevices of the future September 1st, 2015

Nanotech could rid cattle of ticks, with less collateral damage September 1st, 2015

Interviews/Book Reviews/Essays/Reports/Podcasts/Journals/White papers

Hot electrons point the way to perfect light absorption: Physicists study how to achieve perfect absorption of light with the help of rough ultrathin films September 1st, 2015

Using DNA origami to build nanodevices of the future September 1st, 2015

Nanotech could rid cattle of ticks, with less collateral damage September 1st, 2015

Scientists 'squeeze' light one particle at a time: A team of scientists have measured a bizarre effect in quantum physics, in which individual particles of light are said to have been 'squeezed' -- an achievement which at least one textbook had written off as hopeless September 1st, 2015

Research partnerships

Sustainable nanotechnology center September 1st, 2015

$200K Awarded to Develop In Vitro Lung Test for Toxicity of Inhaled Nanomaterials: In Vitro Lung Test Designed to Protect Human Health and Replace Animal Testing September 1st, 2015

Hot electrons point the way to perfect light absorption: Physicists study how to achieve perfect absorption of light with the help of rough ultrathin films September 1st, 2015

Nanocatalysts improve processes for the petrochemical industry August 28th, 2015

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







Car Brands
Buy website traffic