Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > Iron Oxide Nanoparticles Help Investigation of Cognitive Diseases

Abstract:
Iranian researchers from Islamic Azad University, Tehran Branch, in association with researchers from Institute of Biochemistry & Biophysics (IBB) of University of Tehran carried out in vitro an investigation into the changes in the structure of proteins inside brain cells and the interactions of the proteins using iron oxide nanoparticles.

Iron Oxide Nanoparticles Help Investigation of Cognitive Diseases

Tehran, Iran | Posted on November 21st, 2013

The progress of cognitive diseases that do not have any known definite treatment can be prevented if a treatment method is designed and optimized for cognitive diseases such as Alzheimer's-based on controlling metabolism processes of iron oxide in brain cells.

The research showed that microtubules can create magnetic field around themselves due to their dynamic properties and electrical charge. Therefore, they can play role in the transference of electrical signals in brain cells (neurons). It can be said that the protein plays an important role in the transference and probably in saving date in the brain. The malfunction in the performance of microtubules is one of the reasons for the appearance of cognitive diseases such as Alzheimer's.

Iron oxide nanoparticles were firstly produced in this research. Then, microtubule protein was extracted from the brain of a newly-died sheep, and its activity was studied through turbidimetry method. Next, the researchers studied the interaction between nanoparticles and microtubule and tau protein (a protein which is effective in the structural and functional stability of microtubules).

Results of the research showed that iron oxide magnetic nanoparticles and microtubules existing in the neurons can have magnetic interactions with each other, which is essential for the transference and conservation of brain data. However, if the nanoparticles are accumulated in the brain, which can be caused due to the malfunction of iron metabolism in brain cells and due to the improper conservation of iron in a protein called ferritin, the abovementioned interaction may be damaged, and nanoparticles connect with microtubules and tau protein, which results in the instability of microtubular polymers.

A part of the results of the research have been published in February 2013 in Journal of Biological Inorganic Chemistry, vol. 18, issue 3, pp. 357-369.

####

For more information, please click here

Copyright © Fars News Agency

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Haydale Secures Exclusive Development and Supply Agreement with Tantec A/S: New reactors to be built and commissioned by Tantec A/S represent another step forward towards the commercialisation of graphene October 24th, 2014

QuantumWise guides the semiconductor industry towards the atomic scale October 24th, 2014

MEMS & Sensors Technology Showcase: Finalists Announced for MEMS Executive Congress US 2014 October 23rd, 2014

Nanoparticle technology triples the production of biogas October 23rd, 2014

Nanomedicine

NYU Researchers Break Nano Barrier to Engineer the First Protein Microfiber October 23rd, 2014

Iranian Scientists Apply Nanotechnology to Produce Surgery Suture October 23rd, 2014

RF Heating of Magnetic Nanoparticles Improves the Thawing of Cryopreserved Biomaterials October 23rd, 2014

Sopping up proteins with thermosponges: Researchers develop novel nanoparticle platform that proves effective in delivering protein-based drugs October 22nd, 2014

Discoveries

QuantumWise guides the semiconductor industry towards the atomic scale October 24th, 2014

Iranian, Malaysian Scientists Study Nanophotocatalysts for Water Purification October 23rd, 2014

Nanoparticle technology triples the production of biogas October 23rd, 2014

Strengthening thin-film bonds with ultrafast data collection October 23rd, 2014

Announcements

Haydale Secures Exclusive Development and Supply Agreement with Tantec A/S: New reactors to be built and commissioned by Tantec A/S represent another step forward towards the commercialisation of graphene October 24th, 2014

QuantumWise guides the semiconductor industry towards the atomic scale October 24th, 2014

Advancing thin film research with nanostructured AZO: Innovnano’s unique and cost-effective AZO sputtering targets for the production of transparent conducting oxides October 23rd, 2014

Strengthening thin-film bonds with ultrafast data collection October 23rd, 2014

Interviews/Book Reviews/Essays/Reports/Podcasts/Journals

NYU Researchers Break Nano Barrier to Engineer the First Protein Microfiber October 23rd, 2014

Iranian Scientists Apply Nanotechnology to Produce Surgery Suture October 23rd, 2014

Iranian, Malaysian Scientists Study Nanophotocatalysts for Water Purification October 23rd, 2014

Strengthening thin-film bonds with ultrafast data collection October 23rd, 2014

Research partnerships

NYU Researchers Break Nano Barrier to Engineer the First Protein Microfiber October 23rd, 2014

Nanoparticle technology triples the production of biogas October 23rd, 2014

RF Heating of Magnetic Nanoparticles Improves the Thawing of Cryopreserved Biomaterials October 23rd, 2014

Brookhaven Lab Launches Computational Science Initiative:Leveraging computational science expertise and investments across the Laboratory to tackle "big data" challenges October 22nd, 2014

NanoNews-Digest
The latest news from around the world, FREE





  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE