Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Application of Gold Nanosensors to Measure Blood Clotting Agent

Abstract:
Iranian researchers from Shiraz University in association with researchers from Razi Kermanshah University used gold nanoparticles and designed sensors to measure heparin in blood plasmon samples.

Application of Gold Nanosensors to Measure Blood Clotting Agent

Tehran, Iran | Posted on September 24th, 2013

The sensor is not sensitive to the pH of the environment and it can be used at all pH values, including physiologic pH. It has many applications in clinics and hospitals to diagnose the disease.

Heparin plays an important role in the clotting of blood, and its performance depends on its concentration in the blood. Therefore, it is highly important to measure the amount of this material in blood plasmon in patients who suffer from cardiovascular illnesses.

Heparin is a polyanion chemical compound that has negative charges. In the previous methods to measure heparin by using gold nanoparticles, the environment pH had to become acidic so the nanoparticles would have positive charges. According to Coulomb interaction between the positive charges of nanoparticles and negative charges of heparin, the colloidal nanoparticles aggregated and the space between them was very small. As a result, the color of the solution changed due to the changes in gold resonance plasmon spectrum. Ionic liquid based on imidazole were used in this research instead of the common filling agents. By controlling the concentration of ionic liquids, positive charges are formed on the surface of nanoparticles. Interestingly, the positive charge is independent of pH value, and this characteristic was used in this research.

The produced sensor is very sensitive to heparin and it can be used in in-situ analysis. The most important characteristic of the sensor is its functionality at physiologic pH. Results of the research also showed the possibility of the use of a camera to take photos to analyze heparin instead of using spectrophotometer device.

Results of the research have been published in May 2013 in Analyst, vol. 138, pp. 4830-4837.

####

For more information, please click here

Copyright © Fars News Agency

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Nanoparticles Give Antibacterial Properties to Machine-Woven Carpets August 4th, 2015

Nanoparticles used to breach mucus barrier in lungs: Proof-of-concept study conducted in mice a key step toward better treatments for lung diseases August 3rd, 2015

Promising Step Taken in Iran towards Treatment of Spinal Cord Injury August 3rd, 2015

Diagnosis of Salmonella Bacterium-Caused Food Poisoning by Biosensors August 3rd, 2015

Nanomedicine

Nanoparticles used to breach mucus barrier in lungs: Proof-of-concept study conducted in mice a key step toward better treatments for lung diseases August 3rd, 2015

Promising Step Taken in Iran towards Treatment of Spinal Cord Injury August 3rd, 2015

Diagnosis of Salmonella Bacterium-Caused Food Poisoning by Biosensors August 3rd, 2015

Gold-diamond nanodevice for hyperlocalised cancer therapy: Gold nanorods can be used as remote controlled nanoheaters delivering the right amount of thermal treatment to cancer cells, thanks to diamond nanocrystals used as temperature sensors August 1st, 2015

Sensors

Quantum states in a nano-object manipulated using a mechanical system August 3rd, 2015

Diagnosis of Salmonella Bacterium-Caused Food Poisoning by Biosensors August 3rd, 2015

Gold-diamond nanodevice for hyperlocalised cancer therapy: Gold nanorods can be used as remote controlled nanoheaters delivering the right amount of thermal treatment to cancer cells, thanks to diamond nanocrystals used as temperature sensors August 1st, 2015

Advances and Applications in Biosensing, Sensor Power, and Sensor R&D to be Covered at Sensors Global Summit August 1st, 2015

Discoveries

Nanoparticles Give Antibacterial Properties to Machine-Woven Carpets August 4th, 2015

Nanoparticles used to breach mucus barrier in lungs: Proof-of-concept study conducted in mice a key step toward better treatments for lung diseases August 3rd, 2015

Promising Step Taken in Iran towards Treatment of Spinal Cord Injury August 3rd, 2015

Diagnosis of Salmonella Bacterium-Caused Food Poisoning by Biosensors August 3rd, 2015

Announcements

Nanoparticles Give Antibacterial Properties to Machine-Woven Carpets August 4th, 2015

Nanoparticles used to breach mucus barrier in lungs: Proof-of-concept study conducted in mice a key step toward better treatments for lung diseases August 3rd, 2015

Promising Step Taken in Iran towards Treatment of Spinal Cord Injury August 3rd, 2015

Diagnosis of Salmonella Bacterium-Caused Food Poisoning by Biosensors August 3rd, 2015

Interviews/Book Reviews/Essays/Reports/Podcasts/Journals/White papers

Nanoparticles Give Antibacterial Properties to Machine-Woven Carpets August 4th, 2015

MIPT researchers clear the way for fast plasmonic chips August 3rd, 2015

Quantum states in a nano-object manipulated using a mechanical system August 3rd, 2015

Nanoparticles used to breach mucus barrier in lungs: Proof-of-concept study conducted in mice a key step toward better treatments for lung diseases August 3rd, 2015

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project