Nanotechnology Now

Our NanoNews Digest Sponsors



Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > Biodegradable Nanofibrous Scaffold Designed for Cell Growth, Tissue Recovery

Abstract:
Iranian nanomaterial experts in association with pharmaceutical researchers succeeded in designing biodegradable nanofibrous scaffold by using bioactive glass nanoparticles, which is appropriate for cell growth and tissue recovery in the treatment of injured bone tissues.

Biodegradable Nanofibrous Scaffold Designed for Cell Growth, Tissue Recovery

Tehran, Iran | Posted on September 3rd, 2013

The product of this plan has applications in medical fields after the preparation and after passing the complementary in vitro tests as drug carrying scaffold and bioactive agents to grow bone cell and to cure the injured bone tissues.

In order to improve the mechanical properties and bioactivity of the nanofibers, bioactive glass nanoparticles were added while simvastatin drug (aiming to speed up the growth of the bone tissue) was loaded in the fibers to increase the efficiency of the scaffold. Years ago, Hench et al showed that bioactive glasses had good ability to make bonds with bone tissue, and they made desirable joint with the bone. Results of other researches display that simvastatin (the drug to reduce cholesterol in blood) has positive effect on bone metabolism. Therefore, it was decided that these two materials are combined with polycaprolactone nanofibers in this research to produce a nanofibrous scaffold suitable for the bone tissue.

In this research, polycaprolactone composite nanofibers loaded with simvastatin drug and bioactive glass nanoparticles were produced through electrospinning method, and their biological and mechanical properties were investigated in laboratorial and also in human's body simulated media.

Results of biodegradability and drug delivery tests showed that the presence of glass nanoparticles increase the degradability of the nanofiber web in body's simulated media due to their hydrolysis ability in aqueous environment. Therefore, more drug is released in comparison with the nanofibers without nanoparticles.

One of the recent results of the research has been published on 15 July 2013 in Chemical Engineering Journal, vol. 228, pp. 1057-1065.

####

For more information, please click here

Copyright © Fars News Agency

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Vegetable oil ingredient key to destroying gastric disease bacteria: In mice, therapeutic nanoparticles dampen H. pylori bacteria and inflammation that lead to ulcers and gastric cancer November 25th, 2014

Research yields material made of single-atom layers that snap together like Legos November 25th, 2014

Blu-ray disc can be used to improve solar cell performance: Data storage pattern transferred to solar cell increases light absorption November 25th, 2014

A*STAR SIMTech wins international award for breaking new ground in actuators: SIMTech invention can be used in an array of industries, and is critical for next generation ultra-precision systems November 24th, 2014

Nanomedicine

Vegetable oil ingredient key to destroying gastric disease bacteria: In mice, therapeutic nanoparticles dampen H. pylori bacteria and inflammation that lead to ulcers and gastric cancer November 25th, 2014

Research reveals how our bodies keep unwelcome visitors out of cell nuclei November 24th, 2014

ASU, IBM move ultrafast, low-cost DNA sequencing technology a step closer to reality November 24th, 2014

An Inside Job: UC-Designed Nanoparticles Infiltrate, Kill Cancer Cells From Within November 24th, 2014

Discoveries

Vegetable oil ingredient key to destroying gastric disease bacteria: In mice, therapeutic nanoparticles dampen H. pylori bacteria and inflammation that lead to ulcers and gastric cancer November 25th, 2014

Research yields material made of single-atom layers that snap together like Legos November 25th, 2014

Blu-ray disc can be used to improve solar cell performance: Data storage pattern transferred to solar cell increases light absorption November 25th, 2014

An Inside Job: UC-Designed Nanoparticles Infiltrate, Kill Cancer Cells From Within November 24th, 2014

Announcements

Vegetable oil ingredient key to destroying gastric disease bacteria: In mice, therapeutic nanoparticles dampen H. pylori bacteria and inflammation that lead to ulcers and gastric cancer November 25th, 2014

Research yields material made of single-atom layers that snap together like Legos November 25th, 2014

Blu-ray disc can be used to improve solar cell performance: Data storage pattern transferred to solar cell increases light absorption November 25th, 2014

Cooling with the coldest matter in the world November 24th, 2014

Interviews/Book Reviews/Essays/Reports/Podcasts/Journals/White papers

Vegetable oil ingredient key to destroying gastric disease bacteria: In mice, therapeutic nanoparticles dampen H. pylori bacteria and inflammation that lead to ulcers and gastric cancer November 25th, 2014

Research yields material made of single-atom layers that snap together like Legos November 25th, 2014

Blu-ray disc can be used to improve solar cell performance: Data storage pattern transferred to solar cell increases light absorption November 25th, 2014

An Inside Job: UC-Designed Nanoparticles Infiltrate, Kill Cancer Cells From Within November 24th, 2014

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More












ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE