Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > Nanobotmodels offer concept animation of nanorobotic atherosclerosis plaque removement

Abstract:
Atherosclerosis is a major cardiovascular disease involving accumulations of lipids, white blood cells, and other materials on the inside of artery walls. Since the calcification found in the advanced stage of atherosclerosis dramatically enhances the mechanical properties of the plaque, restoring the original lumen of the artery remains a challenge.

Nanobotmodels offer concept animation of nanorobotic atherosclerosis plaque removement

Melitopol, Ukraine | Posted on August 14th, 2013

Calcification [1] forms among vascular smooth muscle cells of the surrounding muscular layer, specifically in the muscle cells adjacent to atheromas and on the surface of atheroma plaques and tissue. In time, as cells die, this leads to extracellular calcium deposits between the muscular wall and outer portion of the atheromatous plaques.

Complications of advanced atherosclerosis are chronic, slowly progressive and cumulative. Most commonly, soft plaque suddenly ruptures, causing the formation of a thrombus that will rapidly slow or stop blood flow, leading to death of the tissues fed by the artery in approximately 5 minutes. This catastrophic event is called an infarction. One of the most common recognized scenarios is called coronary thrombosis of a coronary artery, causing a heart attack. The same process in an artery to the brain is commonly called stroke. Another common scenario in very advanced disease is claudication from insufficient blood supply to the legs, typically caused by a combination of both stenosis and aneurysmal segments narrowed with clots.

Modern medicine use high-speed rotational atherectomy, when performed with an ablating grinder to remove the plaque, produces much better results in the treatment of calcified plaque compared to other methods [2].

However, the high-speed rotation of the Rotablator commercial rotational atherectomy device produces microcavitation, which should be avoided because of the serious complications it can cause. This research involves the development of a high-speed rotational ablation tool that does not generate microcavitation [2].

Future nanomedical devices can avoid this problem and also they can make atherectomy non-invasive and simply procedure.

Nanobotmodels created first artistic representations of a conceptual advanced atherosclerosis plaques removing using medical nanorobotics.

Medical nanorobots called "nano" due to size of their components. These tiny artificial nanoelectromechanical systems will change 90% of traditional medicine treatments, make them fast and more efficient.

Perhaps the best-characterized mechanical nanocomputer is Drexler's rod logic design. In this design, one sliding rod with a knob intersects a second knobbed sliding rod at right angles to the first. Depending upon the position of the first rod, the second may be free to move, or unable to move. This simple blocking interaction serves as the basis for logical operations [3]. The same CPU logic can be used in anti-atherosclerosis nanorobot.

The nanorobot has magnetic marcers - "cores" that can monitor its position inside the blood system with high precision. That is why physicians can operate the nanorobot in real-time inside the bloodstream and physicians can control all the nanorobot's main functions by a remote monitor (like MRI imaging).

With the help of modern monitoring system physicians can control nanorobot's movements and plaque destruction in real-time. It can be possible due to magnetic markers in each medical nanomachine, which will be unique for every device

In this way calcifications will be removed without surgery or another complex medical procedure. Unfortunately, this nanorobotic concept or equal medical treatment will be available only in next decade with proper nanotechnology development.

[1] Bertazzo, S. et al. Nano-analytical electron microscopy reveals fundamental insights into human cardiovascular tissue calcification. Nature Materials 12, 576-583 (2013).

[2] Kim MH, Kim HJ, Kim NN, Yoon HS, Ahn SH. "A rotational ablation tool for calcified atherosclerotic plaque removal", Biomed Microdevices. 2011 Dec;13(6):963-71. doi: 10.1007/s10544-011-9566-y.

[3] Robert A. Freitas Jr., Nanomedicine, Volume I: Basic Capabilities, Landes

####

About Nanobotmodels Company
Nanobotmodels was established in 2007 with the goal of developing highly innovative, digital graphics to depict actual and conceptual technologies via the synergistic fusion of art and science. The still nascent, yet prospectively powerful discipline of nanotechnology is poised to radically transform medicine, engineering, biotechnology, electronics and myriad other sectors in the relative near-term. Hence, visionary artistic renderings that portray various aspects of this exciting nanofuture will be beneficial in facilitating a clear understanding of its fundamental concepts to a broad demographic.

Nanobotmodels generates imaginative and engaging state-of-the-art nanotechnology and nanomedical illustrations and animations. Any prototypical component, device, system or far flung concept that might be conceived of can be translated into captivating and colorful photorealistic animated or static renderings and presentation materials…. We bring them all to life for you!

For more information, please click here

Copyright © Nanobotmodels Company

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Study finds long-term survival of human neural stem cells transplanted into primate brain April 23rd, 2014

High-Performance, Low-Cost Ultracapacitors Built with Graphene and Carbon Nanotubes: Future devices based on technology could bridge gap between batteries and conventional capacitors in portable electronics and hybrid electric vehicles April 23rd, 2014

Guo Lab Shows Potential of RNA as Heat-resistant Polymer Material for Nanoarchitectures April 23rd, 2014

National Space Society Congratulates SpaceX on the Success of CRS-3 and the First Flight of the Falcon 9R April 22nd, 2014

Nanoreporters tell 'sour' oil from 'sweet': Rice University's hydrogen sulfide nanoreporters gather intel on oil before pumping April 22nd, 2014

Videos/Movies

Like a hall of mirrors, nanostructures trap photons inside ultrathin solar cells April 22nd, 2014

Tiny particles could help verify goods: Chemical engineers hope smartphone-readable microparticles could crack down on counterfeiting April 15th, 2014

Nanomedicine

Study finds long-term survival of human neural stem cells transplanted into primate brain April 23rd, 2014

Cloaked DNA nanodevices survive pilot mission: Successful foray opens door to virus-like DNA nanodevices that could diagnose diseased tissues and manufacture drugs to treat them April 22nd, 2014

Berkeley Lab Researchers Demonstrate First Size-based Chromatography Technique for the Study of Living Cells April 22nd, 2014

Amino-functionalized carbon nanotubes act as a carrier for nerve growth factor April 21st, 2014

Announcements

Study finds long-term survival of human neural stem cells transplanted into primate brain April 23rd, 2014

High-Performance, Low-Cost Ultracapacitors Built with Graphene and Carbon Nanotubes: Future devices based on technology could bridge gap between batteries and conventional capacitors in portable electronics and hybrid electric vehicles April 23rd, 2014

Guo Lab Shows Potential of RNA as Heat-resistant Polymer Material for Nanoarchitectures April 23rd, 2014

National Space Society Congratulates SpaceX on the Success of CRS-3 and the First Flight of the Falcon 9R April 22nd, 2014

NanoNews-Digest
The latest news from around the world, FREE







  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE