Nanotechnology Now

Our NanoNews Digest Sponsors
Heifer International

Wikipedia Affiliate Button

Home > Press > Material in dissolvable sutures could treat brain infections, reducing hospital stays

The challenge of delivering to the brain a continuous regimen of antibiotics in case of infection could be met with plastic nanofibers that release medication directly to the affected site.
Credit: iStockphoto/Thinkstock
The challenge of delivering to the brain a continuous regimen of antibiotics in case of infection could be met with plastic nanofibers that release medication directly to the affected site.

Credit: iStockphoto/Thinkstock

Abstract:
A plastic material already used in absorbable surgical sutures and other medical devices shows promise for continuous administration of antibiotics to patients with brain infections, scientists are reporting in a new study. Use of the material, placed directly on the brain's surface, could reduce the need for weeks of costly hospital stays now required for such treatment, they say in the journal ACS Chemical Neuroscience.

Material in dissolvable sutures could treat brain infections, reducing hospital stays

Washington, DC | Posted on August 11th, 2013

Shih-Jung Liu and colleagues explain that infections are life-threatening complications that occur in about 5-10 percent of patients who have brain surgery. Current treatment involves intravenous antibiotics for up to eight weeks and extended, costly hospital stays. Previous studies showed that drug-delivering plastics could release antibiotics directly into the brain. However, additional surgery was needed to remove the plastic when treatment finished. Liu's team sought to develop a biodegradable version using a dissolvable plastic called PLGA.

They describe development of PLGA fibers that release vancomycin, a powerful antibiotic that kills many microbes, including the infamous "MRSA," which shrugs off most other known antibiotics. They tested the fibers in rats, which are stand-ins for humans in these types of studies. The fibers successfully released vancomycin for more than eight weeks in the brain and did so without apparent side effects.

The authors acknowledge funding from Chang Gung Memorial Hospital.

####

About American Chemical Society
The American Chemical Society is a nonprofit organization chartered by the U.S. Congress. With more than 163,000 members, ACS is the world’s largest scientific society and a global leader in providing access to chemistry-related research through its multiple databases, peer-reviewed journals and scientific conferences. Its main offices are in Washington, D.C., and Columbus, Ohio.

For more information, please click here

Contacts:
Shih-Jung Liu, Ph.D.
Biomaterials Lab
Department of Mechanical Engineering
Chang Gung University
259 Wen-Hwa 1st Road
Kwei-Shan
Tao-Yuan 333
Taiwan
Phone: +866-3-2118166
Fax: +866-3-2118558
Email:

Science Inquiries:
Michael Woods
editor

202-872-6293

General Inquiries:
Michael Bernstein

202-872-6042

Copyright © American Chemical Society

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related Links

DOWNLOAD FULL-TEXT ARTICLE - “Biodegradable Drug-Eluting Poly[lactic-co-glycol acid] Nanofibers for the Sustainable Delivery of Vancomycin to Brain Tissue: In Vitro and in Vivo Studies”

Related News Press

News and information

Tracking pollen with quantum dots: A pollination biologist from Stellenbosch University in South Africa is using quantum dots to track the fate of individual pollen grains. This is breaking new ground in a field of research that has been hampered by the lack of a universal method February 17th, 2019

Super-light, super-insulating ceramic aerogel keeps the hottest temperatures at bay February 17th, 2019

Molecular Lego blocks: Chemical data mining boosts search for new organic semiconductors February 15th, 2019

The smallest skeletons in the marine world observed in 3D by synchrotron techniques February 15th, 2019

Nanomedicine

Sensitive sensor detects Down syndrome DNA February 14th, 2019

Laser-induced graphene gets tough, with help: Rice University lab combines conductive foam with other materials for capable new composites February 12th, 2019

Nominations invited for $250,000 Kabiller Prize — the world’s largest monetary award for achievement in nanomedicine: An additional $10,000 award will honor a young investigator in nanoscience, nanomedicine February 7th, 2019

Kanazawa University research: Chirality inversion in a helical molecule at controlled speeds February 6th, 2019

Discoveries

Tracking pollen with quantum dots: A pollination biologist from Stellenbosch University in South Africa is using quantum dots to track the fate of individual pollen grains. This is breaking new ground in a field of research that has been hampered by the lack of a universal method February 17th, 2019

Molecular Lego blocks: Chemical data mining boosts search for new organic semiconductors February 15th, 2019

The smallest skeletons in the marine world observed in 3D by synchrotron techniques February 15th, 2019

Researchers create ultra-lightweight ceramic material that withstands extreme temperatures: UCLA-led team develops highly durable aerogel that could ultimately be an upgrade for insulation on spacecraft February 15th, 2019

Announcements

Tracking pollen with quantum dots: A pollination biologist from Stellenbosch University in South Africa is using quantum dots to track the fate of individual pollen grains. This is breaking new ground in a field of research that has been hampered by the lack of a universal method February 17th, 2019

Super-light, super-insulating ceramic aerogel keeps the hottest temperatures at bay February 17th, 2019

Researchers create ultra-lightweight ceramic material that withstands extreme temperatures: UCLA-led team develops highly durable aerogel that could ultimately be an upgrade for insulation on spacecraft February 15th, 2019

Spintronics by 'straintronics': Switching superferromagnetism with electric-field induced strain February 15th, 2019

Interviews/Book Reviews/Essays/Reports/Podcasts/Journals/White papers

Tracking pollen with quantum dots: A pollination biologist from Stellenbosch University in South Africa is using quantum dots to track the fate of individual pollen grains. This is breaking new ground in a field of research that has been hampered by the lack of a universal method February 17th, 2019

Super-light, super-insulating ceramic aerogel keeps the hottest temperatures at bay February 17th, 2019

NRL, AFRL develop direct-write quantum calligraphy in monolayer semiconductors February 15th, 2019

Researchers create ultra-lightweight ceramic material that withstands extreme temperatures: UCLA-led team develops highly durable aerogel that could ultimately be an upgrade for insulation on spacecraft February 15th, 2019

Alliances/Trade associations/Partnerships/Distributorships

John Chong of Kionix Named Chair of MEMS & Sensors Industry Group Governing Council February 6th, 2019

TOCHA will take a topological approach to the next generation of electronic, photonic and phononic devices January 31st, 2019

Elliot Scientific now representing Digital Holographic Microscopy company Lyncée Tec SA in the UK and Eire January 22nd, 2019

ULVAC Inc., and Oxford Instruments Plasma Technology collaborate to bring Atomic Scale Processing solutions to the Japanese Power and RF markets January 18th, 2019

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project