Nanotechnology Now







Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Gold 'nanoprobes' hold the key to treating killer diseases

This image shows Dr. Sumeet Mahajan at work in the lab.

Credit: The University of Southampton
This image shows Dr. Sumeet Mahajan at work in the lab.

Credit: The University of Southampton

Abstract:
Researchers at the University of Southampton, in collaboration with colleagues at the University of Cambridge, have developed a technique to help treat fatal diseases more effectively. Dr Sumeet Mahajan and his group at the Institute for Life Sciences at Southampton are using gold nanoprobes to identify different types of cells, so that they can use the right ones in stem cell therapies.

Gold 'nanoprobes' hold the key to treating killer diseases

Southampton, UK | Posted on August 7th, 2013

Stem cell therapy is in its infancy, but has the potential to change the way we treat cancer and other life-threatening diseases, by replacing damaged or diseased cells with healthy ones. One of the key limitations of stem cell therapy is identifying the right cells to use for different therapies. This fundamental problem with the treatment is being tackled by this new research.

Dr Mahajan, Senior Chemistry Lecturer in Life Science Interface, says: "Stem cells could hold the key to tackling many diseases. They develop into all the various kinds of cells needed in the body - blood, nerves and organs - but it is almost impossible to tell them apart during their initial development without complex techniques, even with the most advanced microscopes. Up to now, scientists have used intrusive fluorescent markers to tag molecules and track each cell, a process which can render them useless for therapeutic purposes anyway. By using a technique discovered at Southampton in the 1970s, known as Surface Enhanced Raman Spectroscopy (SERS), we have been able to look at adult stem cells on a molecular scale to distinguish one from another, meaning we can still use the cells for therapeutic purposes."

The team who discovered SERS in the 1970s found that by roughening a metal surface upon which they had placed molecules to be examined, they could increase the signal by which they could detect these molecules, by a million times. This allowed them to detect molecules in far smaller quantities than ever before. SERS has been used in many different capacities around the world and across industries, but this new research marks the first time it has been used in the field of cell therapeutics. Dr Mahajan's research could mean that stem cell and other cell-based therapies could be advanced much further than the current most common uses, such as bone marrow transplants.

Dr Mahajan comments: "Scientists studying neurodegenerative diseases such as Parkinson's disease believe replenishing a patient's depleted dopamine-generating cells, may be an effective treatment. However, in order to avoid fatal complications, we must be sure we are using the right type of replacement cells, which the work we are doing at Southampton is enabling us to do. In addition, the technique can also allow us to see if drugs are working effectively in cells, and can also be used to diagnose diseases as well as treat them."

The results of Dr Mahajan's work, funded by the Engineering and Physical Sciences Research Council (EPSRC), have been published in the influential journal Nano Letters. He is collaborating with major pharmaceutical companies to further develop more effective drugs using this technique.

####

About University of Southampton
The University of Southampton is a leading UK teaching and research institution with a global reputation for leading-edge research and scholarship across a wide range of subjects in engineering, science, social sciences, health and humanities.

With over 23,000 students, around 5000 staff, and an annual turnover well in excess of 435 million, the University of Southampton is acknowledged as one of the country's top institutions for engineering, computer science and medicine. We combine academic excellence with an innovative and entrepreneurial approach to research, supporting a culture that engages and challenges students and staff in their pursuit of learning.

The University is also home to a number of world-leading research centres including the Institute of Sound and Vibration Research, the Optoelectronics Research Centre, the Institute for Life Sciences, the Web Science Trust and Doctoral training Centre, the Centre for the Developmental Origins of Health and Disease, the Southampton Statistical Sciences Research Institute and is a partner of the National Oceanography Centre at the Southampton waterfront campus.

About Engineering and Physical Sciences Research Council (EPSRC)

The Engineering and Physical Sciences Research Council (EPSRC) which is funding Dr Mahajan's research project, is the UK's main agency for funding research in engineering and the physical sciences. EPSRC invests around 800 million a year in research and postgraduate training, to help the nation handle the next generation of technological change.

For more information, please click here

Contacts:
Charlotte Woods
Media Relations
University of Southampton
Tel 023 8059 2128 or 07891210483

Follow us on Twitter: http://twitter.com/unisouthampton

Like us on Facebook: http://www.facebook.com/unisouthampton

Copyright © University of Southampton

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related Links

The full paper can be found at this link:

Related News Press

News and information

Toyocolor to Launch New Carbon Nanotube Materials at nano tech 2015 January 24th, 2015

NANOPOSTER 2015 - 5th Virtual Nanotechnology Conference - call for abstracts January 24th, 2015

Nanosensor Used for Simultaneous Determination of Effective Tea Components January 24th, 2015

The latest fashion: Graphene edges can be tailor-made: Rice University theory shows it should be possible to tune material's properties January 24th, 2015

OCSiAl supports NanoART Imagery Contest January 23rd, 2015

Videos/Movies

OCSiAl supports NanoART Imagery Contest January 23rd, 2015

Laser-generated surface structures create extremely water-repellent metals: Super-hydrophobic properties could lead to applications in solar panels, sanitation and as rust-free metals January 20th, 2015

Hydrogels deliver on blood-vessel growth: Rice researchers introduce improved injectable scaffold to promote healing January 20th, 2015

Nanomedicine

Teijin to Participate in Nano Tech 2015 January 22nd, 2015

2nd International Conference on Infectious Diseases & Nanomedicine (December 15-18, 2015, Kathmandu, NEPAL) January 22nd, 2015

Anti-microbial coatings with a long-term effect for surfaces presentation at nano tech 2015 in Japan January 21st, 2015

A spoonful of sugar in silver nanoparticles to regulate their toxicity January 21st, 2015

Discoveries

Nanosensor Used for Simultaneous Determination of Effective Tea Components January 24th, 2015

The latest fashion: Graphene edges can be tailor-made: Rice University theory shows it should be possible to tune material's properties January 24th, 2015

Iranian Scientists Produce Graphene-Based Oxygen Sensor January 23rd, 2015

Silver nanowires demonstrate unexpected self-healing mechanism: The material has potential for flexible electronics January 23rd, 2015

Announcements

Toyocolor to Launch New Carbon Nanotube Materials at nano tech 2015 January 24th, 2015

NANOPOSTER 2015 - 5th Virtual Nanotechnology Conference - call for abstracts January 24th, 2015

Nanosensor Used for Simultaneous Determination of Effective Tea Components January 24th, 2015

The latest fashion: Graphene edges can be tailor-made: Rice University theory shows it should be possible to tune material's properties January 24th, 2015

Interviews/Book Reviews/Essays/Reports/Podcasts/Journals/White papers

Nanosensor Used for Simultaneous Determination of Effective Tea Components January 24th, 2015

New technique helps probe performance of organic solar cell materials January 23rd, 2015

Iranian Scientists Produce Graphene-Based Oxygen Sensor January 23rd, 2015

Silver nanowires demonstrate unexpected self-healing mechanism: The material has potential for flexible electronics January 23rd, 2015

Research partnerships

Wearable sensor clears path to long-term EKG, EMG monitoring January 20th, 2015

Graphene enables all-electrical control of energy flow from light emitters: First signatures of graphene plasmons at telecommunications wavelength revealed January 20th, 2015

Charge instability detected across all types of copper-based superconductors: Findings may help researchers synthesize materials that can superconduct at room temperature January 16th, 2015

Gold nanoparticles show promise for early detection of heart attacks: NYU School of Engineering Professors collaborate with researchers from Peking University on a new test strip January 15th, 2015

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More










ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2015 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE