- About Us
- Career Center
- Nano-Social Network
- Nano Consulting
- My Account
Polyaniline biosensors modified with gold nanoparticles which are proper for clinical diagnosis and in laboratories to diagnose cancer were produced by Iranian researchers in Sharif University of Technology.
"At first, polyaniline film and gold nanoparticles were grown through electrochemical methods on the graphite surface of printing electrode. Electrodes modified with polyaniline and gold nanoparticles were coated by a monolayer of 17-mer thiol-tethered DNA probe and 6-mercapto-1-hexanol (MCH). Then, due to the strong interaction of streptavidin and biotin, the enzyme containing streptavidin is attached to the biotinylated monolayer of olioligonucleotide that has been attached to the DNA molecule on the surface," Dr. Reihaneh Sadat Saberi, PhD in analytical chemistry from Sharif University of Technology, stated about the research.
She pointed to the precise measures undertaken in the research, and said, "Since the appropriate and homogenous distribution of gold nanoparticles on the biosensor surface is important in the performance of the biosensor, a bed of polyaniline was firstly polymerized on the carbon surface of the electrode. Then, gold nanoparticles were added to the prepared bed in order to obtain a homogenous distribution."
The biosensor has desirable selectivity and repeatability. Therefore, the modified electrode can be used in the stabilization of phosphatase enzyme as well as in the stabilization of other biological materials. In addition, the biosensor can be used in clinical diagnosis and in the laboratories to diagnose cancer in order to detect cancer tissues.
Results of the research have been published in Electroanalysis on 22 April 2013.
For more information, please click here
Copyright © Fars News AgencyIf you have a comment, please Contact us.
Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.
|Related News Press|
News and information
The NanoWizard® AFM from JPK is applied for interdisciplinary research at the University of South Australia for applications including smart wound healing and how plants can protect themselves from toxins July 26th, 2016
Accurate design of large icosahedral protein nanocages pushes bioengineering boundaries: Scientists used computational methods to build ten large, two-component, co-assembling icosahedral protein complexes the size of small virus coats July 25th, 2016
Ultrasensitive sensor using N-doped graphene July 26th, 2016
Easier, faster, cheaper: A full-filling approach to making nanotubes of consistent quality: Approach opens a straightforward route for engineering the properties of single-wall carbon nanotubes July 19th, 2016