Nanotechnology Now







Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > The Diabetes ‘Breathalyzer’: Pitt chemists demonstrate sensor technology that could detect and monitor diabetes through breath analysis alone

A transmission electron microscopy image of the hybrid material revealing the formation of “titanium dioxide on a stick.”
A transmission electron microscopy image of the hybrid material revealing the formation of “titanium dioxide on a stick.”

Abstract:
Diabetes patients often receive their diagnosis after a series of glucose-related blood tests in hospital settings, and then have to monitor their condition daily through expensive, invasive methods. But what if diabetes could be diagnosed and monitored through cheaper, noninvasive methods?

The Diabetes ‘Breathalyzer’: Pitt chemists demonstrate sensor technology that could detect and monitor diabetes through breath analysis alone

Pittsburgh, PA | Posted on June 10th, 2013

Chemists at the University of Pittsburgh have demonstrated a sensor technology that could significantly simplify the diagnosis and monitoring of diabetes through breath analysis alone. Their findings were published in the latest issue of the Journal of the American Chemical Society (JACS).

Even before blood tests are administered, those with diabetes often recognize the condition's symptoms through their breath acetone—a characteristic "fruity" odor that increases significantly with high glucose levels. The Pitt team was interested in this biomarker as a possible diagnostic tool.

"Once patients are diagnosed with diabetes, they have to monitor their condition for the rest of their lives," said Alexander Star, principal investigator of the project and Pitt associate professor of chemistry. "Current monitoring devices are mostly based on blood glucose analysis, so the development of alternative devices that are noninvasive, inexpensive, and provide easy-to-use breath analysis could completely change the paradigm of self-monitoring diabetes."

Together with his colleagues—Dan Sorescu, a research physicist at the National Energy Technology Laboratory, and Mengning Ding, a Pitt graduate student studying chemistry—Star used what's called a "sol-gel approach," a method for using small molecules (often on a nanoscale level) to produce solid materials. The team combined titanium dioxide—an inorganic compound widely used in body-care products such as makeup—with carbon nanotubes, which acted as "skewers" to hold the particles together. These nanotubes were used because they are stronger than steel and smaller than any element of silicon-based electronics.

This method, which the researchers playfully call "titanium dioxide on a stick," effectively combined the electrical properties of the tubes with the light-illuminating powers of the titanium dioxide. They then created the sensor device by using these materials as an electrical semiconductor, measuring its electrical resistance (the sensor's signal).

The researchers found the sensor could be activated with light to produce an electrical charge. This prompted them to "cook" the "skewers" in the sensor under ultraviolet light to measure acetone vapors—which they found were lower than previously reported sensitivities.

"Our measurements have excellent detection capabilities," said Star. "If such a sensor could be developed and commercialized, it could transform the way patients with diabetes monitor their glucose levels."

The team is currently working on a prototype of the sensor, with plans to test it on human breath samples soon.

The paper, "Photoinduced Charge Transfer and Acetone Sensitivity of Single-Walled Carbon Nanotube-Titanium Dioxide Hybrids," was first published in JACS online June 5. The work was performed in support of ongoing research at the National Energy Technology Laboratory.

####

For more information, please click here

Contacts:
B. Rose Huber

412-624-4356
Cell: 412-328-6008

Copyright © University of Pittsburgh

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

A first glimpse inside a macroscopic quantum state March 28th, 2015

DFG to Establish One Clinical Research Unit and Five Research Units: New Projects to Investigate Complications in Pregnancy, Particle Physics, Nanoparticles, Implants and Transport Planning / Approximately 13 Million Euros in Funding for an Initial Three-Year Period March 28th, 2015

Chemists make new silicon-based nanomaterials March 27th, 2015

UT Dallas engineers twist nanofibers to create structures tougher than bulletproof vests March 27th, 2015

Nanotubes/Buckyballs

Carbon nanotube fibers make superior links to brain: Rice University invention provides two-way communication with neurons March 25th, 2015

Iranian Scientists Eliminate Expensive Materials from Diabetes Diagnosis Sensors March 25th, 2015

Effect of Carbon Nanotubes on Properties of Cement Composites Studied in Iran March 23rd, 2015

First proof of isolated attosecond pulse generation at the carbon K-edge March 20th, 2015

Nanomedicine

Novel nanoparticle therapy promotes wound healing March 27th, 2015

Graphene reduces wear of alumina ceramic March 26th, 2015

Application of Graphene Oxide in Body Implants in Iran March 26th, 2015

Nanotechnology in Medical Devices Market is expected to reach $8.5 Billion by 2019 March 25th, 2015

Sensors

UW scientists build a nanolaser using a single atomic sheet March 24th, 2015

Iranian Researchers Present Model to Determine Dynamic Behavior of Nanostructures March 24th, 2015

Nanodevice Invented in Iran to Detect Hydrogen Sulfide in Oil, Gas Industry March 20th, 2015

LamdaGen Corporation Launches Taiwan Diagnostic Subsidiary March 19th, 2015

Discoveries

A first glimpse inside a macroscopic quantum state March 28th, 2015

UT Dallas engineers twist nanofibers to create structures tougher than bulletproof vests March 27th, 2015

Novel nanoparticle therapy promotes wound healing March 27th, 2015

Designer's toolkit for dynamic DNA nanomachines: Arm-waving nanorobot signals new flexibility in DNA origami March 27th, 2015

Announcements

A first glimpse inside a macroscopic quantum state March 28th, 2015

DFG to Establish One Clinical Research Unit and Five Research Units: New Projects to Investigate Complications in Pregnancy, Particle Physics, Nanoparticles, Implants and Transport Planning / Approximately 13 Million Euros in Funding for an Initial Three-Year Period March 28th, 2015

Designer's toolkit for dynamic DNA nanomachines: Arm-waving nanorobot signals new flexibility in DNA origami March 27th, 2015

Using magnetic fields to understand high-temperature superconductivity: Los Alamos explores experimental path to potential 'next theory of superconductivity' March 27th, 2015

Interviews/Book Reviews/Essays/Reports/Podcasts/Journals/White papers

A first glimpse inside a macroscopic quantum state March 28th, 2015

Chemists make new silicon-based nanomaterials March 27th, 2015

UT Dallas engineers twist nanofibers to create structures tougher than bulletproof vests March 27th, 2015

Novel nanoparticle therapy promotes wound healing March 27th, 2015

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More










ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2015 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE