Nanotechnology Now







Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > The Diabetes ‘Breathalyzer’: Pitt chemists demonstrate sensor technology that could detect and monitor diabetes through breath analysis alone

A transmission electron microscopy image of the hybrid material revealing the formation of “titanium dioxide on a stick.”
A transmission electron microscopy image of the hybrid material revealing the formation of “titanium dioxide on a stick.”

Abstract:
Diabetes patients often receive their diagnosis after a series of glucose-related blood tests in hospital settings, and then have to monitor their condition daily through expensive, invasive methods. But what if diabetes could be diagnosed and monitored through cheaper, noninvasive methods?

The Diabetes ‘Breathalyzer’: Pitt chemists demonstrate sensor technology that could detect and monitor diabetes through breath analysis alone

Pittsburgh, PA | Posted on June 10th, 2013

Chemists at the University of Pittsburgh have demonstrated a sensor technology that could significantly simplify the diagnosis and monitoring of diabetes through breath analysis alone. Their findings were published in the latest issue of the Journal of the American Chemical Society (JACS).

Even before blood tests are administered, those with diabetes often recognize the condition's symptoms through their breath acetone—a characteristic "fruity" odor that increases significantly with high glucose levels. The Pitt team was interested in this biomarker as a possible diagnostic tool.

"Once patients are diagnosed with diabetes, they have to monitor their condition for the rest of their lives," said Alexander Star, principal investigator of the project and Pitt associate professor of chemistry. "Current monitoring devices are mostly based on blood glucose analysis, so the development of alternative devices that are noninvasive, inexpensive, and provide easy-to-use breath analysis could completely change the paradigm of self-monitoring diabetes."

Together with his colleagues—Dan Sorescu, a research physicist at the National Energy Technology Laboratory, and Mengning Ding, a Pitt graduate student studying chemistry—Star used what's called a "sol-gel approach," a method for using small molecules (often on a nanoscale level) to produce solid materials. The team combined titanium dioxide—an inorganic compound widely used in body-care products such as makeup—with carbon nanotubes, which acted as "skewers" to hold the particles together. These nanotubes were used because they are stronger than steel and smaller than any element of silicon-based electronics.

This method, which the researchers playfully call "titanium dioxide on a stick," effectively combined the electrical properties of the tubes with the light-illuminating powers of the titanium dioxide. They then created the sensor device by using these materials as an electrical semiconductor, measuring its electrical resistance (the sensor's signal).

The researchers found the sensor could be activated with light to produce an electrical charge. This prompted them to "cook" the "skewers" in the sensor under ultraviolet light to measure acetone vapors—which they found were lower than previously reported sensitivities.

"Our measurements have excellent detection capabilities," said Star. "If such a sensor could be developed and commercialized, it could transform the way patients with diabetes monitor their glucose levels."

The team is currently working on a prototype of the sensor, with plans to test it on human breath samples soon.

The paper, "Photoinduced Charge Transfer and Acetone Sensitivity of Single-Walled Carbon Nanotube-Titanium Dioxide Hybrids," was first published in JACS online June 5. The work was performed in support of ongoing research at the National Energy Technology Laboratory.

####

For more information, please click here

Contacts:
B. Rose Huber

412-624-4356
Cell: 412-328-6008

Copyright © University of Pittsburgh

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Evidence mounts for quantum criticality theory: Findings bolster theory that quantum fluctuations drive strange electronic phenomena January 30th, 2015

Everything You Need To Know About Nanopesticides January 30th, 2015

DNA nanoswitches reveal how life's molecules connect: An accessible new way to study molecular interactions could lower cost and time associated with discovering new drugs January 30th, 2015

Crystal light: New light-converting materials point to cheaper, more efficient solar power: University of Toronto engineers study first single crystal perovskites for new solar cell and LED applications January 30th, 2015

Nanotubes/Buckyballs

Chromium-centered cycloparaphenylene rings for making functionalized nanocarbons January 26th, 2015

GS7 Graphene Sensor maybe Solution in Fight Against Cancer January 25th, 2015

Toyocolor to Launch New Carbon Nanotube Materials at nano tech 2015 January 24th, 2015

Carbon nanotube finding could lead to flexible electronics with longer battery life January 14th, 2015

Nanomedicine

DNA nanoswitches reveal how life's molecules connect: An accessible new way to study molecular interactions could lower cost and time associated with discovering new drugs January 30th, 2015

Made-in-Singapore rapid test kit detects dengue antibodies from saliva: IBN's MedTech innovation simplifies diagnosis of infectious diseases January 29th, 2015

Iranian Researchers Planning to Produce Edible Insulin January 28th, 2015

Nanoparticles that deliver oligonucleotide drugs into cells described in Nucleic Acid Therapeutics January 28th, 2015

Sensors

Detection of Heavy Metals in Samples with Naked Eye January 26th, 2015

GS7 Graphene Sensor maybe Solution in Fight Against Cancer January 25th, 2015

Nanosensor Used for Simultaneous Determination of Effective Tea Components January 24th, 2015

Iranian Scientists Produce Graphene-Based Oxygen Sensor January 23rd, 2015

Discoveries

Evidence mounts for quantum criticality theory: Findings bolster theory that quantum fluctuations drive strange electronic phenomena January 30th, 2015

Everything You Need To Know About Nanopesticides January 30th, 2015

DNA nanoswitches reveal how life's molecules connect: An accessible new way to study molecular interactions could lower cost and time associated with discovering new drugs January 30th, 2015

Crystal light: New light-converting materials point to cheaper, more efficient solar power: University of Toronto engineers study first single crystal perovskites for new solar cell and LED applications January 30th, 2015

Announcements

Evidence mounts for quantum criticality theory: Findings bolster theory that quantum fluctuations drive strange electronic phenomena January 30th, 2015

Everything You Need To Know About Nanopesticides January 30th, 2015

DNA nanoswitches reveal how life's molecules connect: An accessible new way to study molecular interactions could lower cost and time associated with discovering new drugs January 30th, 2015

Crystal light: New light-converting materials point to cheaper, more efficient solar power: University of Toronto engineers study first single crystal perovskites for new solar cell and LED applications January 30th, 2015

Interviews/Book Reviews/Essays/Reports/Podcasts/Journals/White papers

DNA nanoswitches reveal how life's molecules connect: An accessible new way to study molecular interactions could lower cost and time associated with discovering new drugs January 30th, 2015

Crystal light: New light-converting materials point to cheaper, more efficient solar power: University of Toronto engineers study first single crystal perovskites for new solar cell and LED applications January 30th, 2015

Discovery Channel taps Angstron Materials for segment featuring graphene advances January 29th, 2015

Iranian Scientists Use MOFs to Eliminate Dye Pollutants January 29th, 2015

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More










ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2015 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE