Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > New microfluidic method expands toolbox for nanoparticle manipulation

The 2-D microfluidic trap. a) Optical micrograph of a microfluidic manipulation device. Single particles are confined at a predetermined location within the junction of two perpendicular microchannels (trapping region). Two on-chip membrane valves (black) positioned above one inlet channel and one outlet channel are used as metering valves to control the relative flow rates through the opposing channels (red), thereby manipulating and trapping particles at the microchannel junction. b) Schematic of 2-D particle trapping. Two opposing laminar streams meet at the intersection of two perpendicular microchannels, creating a well-defined flow field containing a stagnation point where an object is trapped. c) The microfluidic manipulation device consists of a glass coverslip and a PDMS slab containing the microchannels and valves. Reprinted with permission 2013 American Chemical Society.
The 2-D microfluidic trap. a) Optical micrograph of a microfluidic manipulation device. Single particles are confined at a predetermined location within the junction of two perpendicular microchannels (trapping region). Two on-chip membrane valves (black) positioned above one inlet channel and one outlet channel are used as metering valves to control the relative flow rates through the opposing channels (red), thereby manipulating and trapping particles at the microchannel junction. b) Schematic of 2-D particle trapping. Two opposing laminar streams meet at the intersection of two perpendicular microchannels, creating a well-defined flow field containing a stagnation point where an object is trapped. c) The microfluidic manipulation device consists of a glass coverslip and a PDMS slab containing the microchannels and valves.

Reprinted with permission 2013 American Chemical Society.

Abstract:
Researchers at the University of Illinois at Urbana-Champaign have developed a new flow-based method for manipulating and confining single particles in free solution, a process that will help address current challenges faced by nanoscientists and engineers.

New microfluidic method expands toolbox for nanoparticle manipulation

Urbana, IL | Posted on June 5th, 2013

"This method is a first-of-its-kind tool for manipulation and trapping of small nanoparticles in solution," explained Charles M. Schroeder, an assistant professor in the Department of Chemical and Biomolecular Engineering at Illinois. "Using fluid flow in a microfluidic device means that electrical, magnetic, optical, or acoustic force fields are not necessary."

The new method and the research to develop it were published in the May 2013 issue of Nano Letters, in a paper, "Manipulation and Confinement of Single Particles Using Fluid Flow," authored by Schroeder and postdoctoral researcher Melikhan Tanyeri. The research was performed in Schroeder's laboratory located in Roger Adams Lab on the Illinois campus.

Today, fine-scale manipulation of small particles remains a major challenge in the field. Current methods for particle trapping mainly rely on electrokinetic, magnetic, or optical force fields, which may not be compatible with biomolecules or biological systems.

Together, Schroeder and Tanyeri developed a "microfluidic trap" capable of 2-D particle manipulation using the sole action of fluid flow.

Schroeder and researchers demonstrate several unique features of the microfluidic trap, including 2-D manipulation of particles as small as 500 nanometers in size in water, with a positioning precision of only about 180 nanometers, trapping of particles as small as 100 nanometers, and active control over the solution conditions of a trapped particle. All of this is achieved with a simple PDMS-based microfluidic device without the need for complex instrumentation for optical trapping or electric field generation.

"The microfluidic trap provides a fundamentally new method for the trapping and analysis of single particles or single molecules, complementing existing techniques," Schroeder said. "Our new technology will find pervasive use in interdisciplinary fields such as nanoscience, materials science, complex fluids, soft materials, microbiology, and molecular biology."

Schroeder and Tanyeri said they now have the ability to trap a range of particle sizes.

"Unlike existing methods such as conventional optical or magnetic traps, the microfluidic trap will allow for trapping of tiny nanoparticles, less than 30 nanometers in free solution," Tanyeri said.

With the precise positional control of single nanoparticles in free solution, scientists will be able to explore new technologies, from molecular engineering to bottom-up assembly of nanostructures.

"Fluidic-directed assembly may further enhance existing lithographic, self-assembly, and surface patterning approaches for fabricating nanoscale functional materials and devices," Tanyeri said. "This is a key technological advance that will help to address problems in nanoscience and engineering that are inaccessible to current methods, such as directed assembly and patterning of soft materials."

####

For more information, please click here

Contacts:
Charles M. Schroeder

217-333-3906

Writer:
Sarah Williams
assistant director of communications
Department of Chemical and Biomolecular Engineering
217/244-0541

Copyright © University of Illinois College of Engineering

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Chains of nanogold forged with atomic precision September 23rd, 2016

Tattoo therapy could ease chronic disease: Rice-made nanoparticles tested at Baylor College of Medicine may help control autoimmune diseases September 23rd, 2016

Nanotech Grants Options September 22nd, 2016

Coffee-infused foam removes lead from contaminated water September 21st, 2016

Microfluidics/Nanofluidics

Novel nanoscale detection of real-time DNA amplification holds promise for diagnostics: Research team led by Nagoya University develop a label-free method for detecting DNA amplification in real time based on refractive index changes in diffracted light September 12th, 2016

W.M. Keck Foundation awards Cal State LA a $375,000 research and education grant August 4th, 2016

Researchers invent 'smart' thread that collects diagnostic data when sutured into tissue: Advances could pave way for new generation of implantable and wearable diagnostics July 18th, 2016

Droplets finally all the same size -- in a nanodroplet library June 20th, 2016

Self Assembly

First multicellular organism inspires the design of better cancer drugs September 15th, 2016

A versatile method to pattern functionalized nanowires: A team of researchers from Hokkaido University has developed a versatile method to pattern the structure of 'nanowires,' providing a new tool for the development of novel nanodevices September 9th, 2016

Location matters in the self-assembly of nanoclusters: Iowa State University scientists have developed a new formulation to explain an aspect of the self-assembly of nanoclusters on surfaces that has broad applications for nanotechnology September 8th, 2016

Smarter self-assembly opens new pathways for nanotechnology: Brookhaven Lab scientists discover a way to create billionth-of-a-meter structures that snap together in complex patterns with unprecedented efficiency August 9th, 2016

Discoveries

Chains of nanogold forged with atomic precision September 23rd, 2016

Tattoo therapy could ease chronic disease: Rice-made nanoparticles tested at Baylor College of Medicine may help control autoimmune diseases September 23rd, 2016

Speedy bacteria detector could help prevent foodborne illnesses September 21st, 2016

Coffee-infused foam removes lead from contaminated water September 21st, 2016

Announcements

Chains of nanogold forged with atomic precision September 23rd, 2016

Tattoo therapy could ease chronic disease: Rice-made nanoparticles tested at Baylor College of Medicine may help control autoimmune diseases September 23rd, 2016

Nanotech Grants Options September 22nd, 2016

Coffee-infused foam removes lead from contaminated water September 21st, 2016

Printing/Lithography/Inkjet/Inks/Bio-printing

Iran to hold intl. school on application of nanomaterials in medicine September 20th, 2016

Tailored probes for atomic force microscopes: 3-D laser lithography enhances microscope for studying nanostructures in biology and engineering/ publication in Applied Physics Letters August 11th, 2016

Smarter self-assembly opens new pathways for nanotechnology: Brookhaven Lab scientists discover a way to create billionth-of-a-meter structures that snap together in complex patterns with unprecedented efficiency August 9th, 2016

Nanoscientists develop the 'ultimate discovery tool': Rapid discovery power is similar to what gene chips offer biology June 25th, 2016

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







Car Brands
Buy website traffic