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Iranian researchers produced new nano-radiopharmaceuticals with the ability to accumulate in fibrosarcoma tumor for the timely diagnosis of tumors and to take images from them.
They also increased the adsorption of nano-radiopharmaceuticals by adding the vitamin favored by the cancer cells.
The main purpose in this research was to study the effects of nanomaterials labeled as gallium-67 radioisotope in order to produce a radio drug favored by cancer cells and to increase the adsorption of the radio drug in cancer tissues. Therefore, the required studies were carried out at the beginning, and various methods for labeling nanomaterials were evaluated. After designing the final method, it was labeled with gallium-67 (one of the important radioisotopes for diagnosis), which produced [67Ga]-SPION-folate.
In this research, the abovementioned nano-radiopharmaceuticals were injected to rats that suffered from fibrosarcoma tumor. Results showed that the adsorption of the nano-radiopharmaceuticals increased when the vitamins favored by cancer cells were added to it. Despite the promising results and according to Hoseini, one of the researchers of the plan, complementary studies must be carried out on this drug to be used in clinical treatments taking into account the importance of the use of drugs in patience.
Results of the research have been published in detail in 2012 in Journal of Cancer Research and Therapeutics, vol. 8, issue 2, pp. 204-208.
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