Nanotechnology Now

Our NanoNews Digest Sponsors



Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > Team creates MRI for the nanoscale

A tiny defect, called a nitrogen vacancy (NV), inside a diamond enabled researchers to detect the magnetic resonance of organic molecules in the same way an MRI produces images of a tissue or an organ.
A tiny defect, called a nitrogen vacancy (NV), inside a diamond enabled researchers to detect the magnetic resonance of organic molecules in the same way an MRI produces images of a tissue or an organ.

Abstract:
An international team of researchers including CCNY and the University of Stuttgart have opened the door for MRI technology at the nanoscale. Using tiny defects in diamonds they sensed the magnetic resonance of molecules to peer down to the level of atoms.

Team creates MRI for the nanoscale

New York, NY | Posted on February 13th, 2013

Magnetic resonance imaging (MRI) reveals details of living tissues, diseased organs and tumors inside the body without x-rays or surgery. What if the same technology could peer down to the level of atoms? Doctors could make visual diagnoses of a person's molecules - examining damage on a strand of DNA, watching molecules misfold, or identifying a cancer cell by the proteins on its surface.


Now Dr. Carlos Meriles, associate professor of physics at The City College of New York, and an international team of researchers at the University of Stuttgart and elsewhere have opened the door for nanoscale MRI. They used tiny defects in diamonds to sense the magnetic resonance of molecules. They reported their results in the February 1 issue of Science.

"It is bringing MRI to a level comparable to an atomic force microscope," said Professor Meriles, referring to the device that traces the contours of atoms or tugs on a molecule to measure its strength. A nanoscale MRI could display how a molecule moves without touching it.

"Standard MRI typically gets to a resolution of 100 microns," about the width of a human hair, said Professor Meriles. "With extraordinary effort," he said, "it can get down to about 10 microns" - the width of a couple of blood cells. Nanoscale MRI would have a resolution 1,000 to 10,000 times better.

To try to pick up magnetic resonance on such a small scale, the team took advantage of the spin of protons in an atom, a property usually used to investigate quantum computing. In particular, they used minute imperfections in diamonds.

Diamonds are crystals made up almost entirely of carbon atoms. When a nitrogen atom lodges next to a spot where a carbon atom is missing, however, it creates a defect known as a nitrogen-vacancy (NV) center.

"These imperfections turn out to have a spin - like a little compass - and have some remarkable properties," noted Professor Meriles. In the last few years, researchers realized that these NV centers could serve as very sensitive sensors. They can pick up the magnetic resonance of nearby atoms in a cell, for example. But unlike the atoms in a cell, the NVs shine when a light is directed at them, signaling what their spin is. If you illuminate it with green light it flashes red back.

"It is a form of what is called optically detected magnetic resonance," he said. Like a hiker flashing Morse code on a hillside, the sensor "sends back flashes to say it is alive and well."

"The NV can also be thought of as an atomic magnet. You can manipulate the spin of that atomic magnet just like you do with MRI by applying a radio frequency or radio pulses," Professor Meriles explained. The NV responds. Shine a green light at it when the spin is pointing up and it will respond with brighter red light. A down spin gives a dimmer red light.

Professor Mireles has written on the theoretical underpinnings of the work and proposed the the project to the team, led by Professor Jörg Wrachtrup — a physicist at the University of Stuttgart in Germany — with the assistance of postdoctoral researcher Friedemann Reinhard and collaborators from the University of Bochum and the University of Science and Technology of China. Professor Wrachtrup heads a leading group studying such defects.

In the lab, graduate student Tobias Staudacher — the first author in this work — used NVs that had been created just below the diamond's surface by bombarding it with nitrogen atoms. The team detected magnetic resonance within a film of organic material applied to the surface, just as one might examine a thin film of cells or tissue.

"Ultimately," said Professor Meriles, "One will use a nitrogen-vacancy mounted on the tip of an atomic force microscope - or an array of NVs distributed on the diamond surface - to allow a scanning view of a cell, for example, to probe nuclear spins with a resolution down to a nanometer or perhaps better."

####

For more information, please click here

Contacts:
Jessa Netting

212-650-7615

Copyright © City College of New York

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related Links

Wrachtrup group:

Meriles group:

Reference:

Related News Press

News and information

NREL Announces New Center Directors to lead R&D, Analysis Efforts September 30th, 2014

Yale University and Leica Microsystems Partner to Establish Microscopy Center of Excellence: Yale Welcomes Scientists to Participate in Core Facility Opening and Super- Resolution Workshops October 20 Through 31, 2014 September 30th, 2014

Speed at its limits September 30th, 2014

Research mimics brain cells to boost memory power September 30th, 2014

Imaging

Yale University and Leica Microsystems Partner to Establish Microscopy Center of Excellence: Yale Welcomes Scientists to Participate in Core Facility Opening and Super- Resolution Workshops October 20 Through 31, 2014 September 30th, 2014

Discoveries

Research mimics brain cells to boost memory power September 30th, 2014

Ad-REIC vaccine: A magic bullet for cancer treatment September 30th, 2014

New Topical Hemostatic Agent: Neutral Self-Assembling Peptide Hydrogel September 30th, 2014

Chemical interactions between silver nanoparticles and thiols: A comparison of mercaptohexanol again September 30th, 2014

Announcements

Park Systems Announces Outsourced Analytical Services Including AFM Surface Imaging, Data Analysis and Interpretation September 30th, 2014

Ad-REIC vaccine: A magic bullet for cancer treatment September 30th, 2014

New Topical Hemostatic Agent: Neutral Self-Assembling Peptide Hydrogel September 30th, 2014

Chemical interactions between silver nanoparticles and thiols: A comparison of mercaptohexanol again September 30th, 2014

Tools

Yale University and Leica Microsystems Partner to Establish Microscopy Center of Excellence: Yale Welcomes Scientists to Participate in Core Facility Opening and Super- Resolution Workshops October 20 Through 31, 2014 September 30th, 2014

Park Systems Announces Outsourced Analytical Services Including AFM Surface Imaging, Data Analysis and Interpretation September 30th, 2014

Iranian Scientists Determine Grain Size, Minimize Time of Nanocomposite Synthesis September 29th, 2014

Oxford Instruments launches 3rd annual Indian nanotechnology seminars in Kolkata and Delhi - sharing expertise with Nanotechnology researchers in India September 25th, 2014

Research partnerships

Research mimics brain cells to boost memory power September 30th, 2014

'Pixel' engineered electronics have growth potential: Rice, Oak Ridge, Vanderbilt, Penn scientists lead creation of atom-scale semiconducting composites September 29th, 2014

Teijin Aramid’s carbon nanotube fibers awarded with Paul Schlack prize: New generation super fibers bring wave of innovations to fiber market September 25th, 2014

Smallest-possible diamonds form ultra-thin nanothread September 25th, 2014

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE