Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > 2 problems in chemical catalysis solved: University of Jyvaskyla Department of Chemistry and NanoScience Center

This image shows a novel bifunctional catalyst for the Mannich reaction.

Credit: Professor Petri Pihko
This image shows a novel bifunctional catalyst for the Mannich reaction.

Credit: Professor Petri Pihko

Abstract:
The research group of Professor Petri Pihko at the Department of Chemistry and the NanoScience Center of the University of Jyväskylä has solved two acute problems in chemical catalysis. The research has been funded by the Academy of Finland.

2 problems in chemical catalysis solved: University of Jyvaskyla Department of Chemistry and NanoScience Center

Finland | Posted on December 20th, 2012

In the first project, the researchers designed a novel intramolecularly assisted catalyst for the synthesis of beta amino acids. Previously published catalysts work only with aromatic side chains in the imines, but the new catalyst designed at Jyväskylä does not have this limitation. The new method might find uses in the synthesis of beta amino acids, which are important building blocks for chemical biology. For the understanding of the catalytic mechanism and design of the catalyst, the researchers collaborated with the group of Imre Pápai (Hungarian Academy of Sciences, computational studies) and Academy Professor Kari Rissanen (Jyväskylä, X-ray characterisation of catalysts).

In the second project, the researchers identified a completely new mechanism for the amine-catalysed Michael addition reaction between aldehydes and nitroalkenes. The mechanism has been a source of intense discussion within the scientific community, with the groups of Professor Yujiro Hayashi (Tokyo), Professor Donna Blackmond (La Jolla, USA) and Professor Dieter Seebach (ETH, Switzerland) each presenting different possible mechanisms.

The new model proposed by the Pihko and Papai groups includes a new species, a six-membered ring, as the key on-cycle intermediate that is protonated in the rate-determining step. The work is a combination of computational and experimental studies that complement each other in understanding the mechanism and demonstrate how difficult mechanistic puzzles can be solved by joining the forces of both approaches.

The research results have been published in Angewandte Chemie.

####

For more information, please click here

Contacts:
Petri Pihko

358-505-289-132

Copyright © Academy of Finland

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related Links

Download article:

Download article:

Related News Press

News and information

Harris & Harris Group Notes Announcements by Its Portfolio Companies During the Third Quarter of 2016 September 30th, 2016

INVECAS to Enable ASIC Designs for Tomorrow’s Intelligent Systems on GLOBALFOUNDRIES' FDX™ Technology: INVECAS to Collaborate with GLOBALFOUNDRIES to Provide IP and End-to-End ASIC Design Services on 22FDX® and 12FDX™ Technologies September 30th, 2016

How to power up graphene implants without frying cells: New analysis finds way to safely conduct heat from graphene to biological tissues September 30th, 2016

Innovation in Nanotechnology is Focus of Symposium: Annual event brings international experts to Northwestern Oct. 6 September 29th, 2016

Chemistry

Chains of nanogold – forged with atomic precision September 23rd, 2016

Carbon-coated iron catalyst structure could lead to more-active fuel cells September 15th, 2016

Researchers build world's largest database of crystal surfaces and shapes September 14th, 2016

On-surface chemistry leads to novel products: On-surface chemical Reactions can lead to novel chemical compounds not yet synthesized by solution chemistry. September 13th, 2016

Discoveries

How to power up graphene implants without frying cells: New analysis finds way to safely conduct heat from graphene to biological tissues September 30th, 2016

Nanosensors could help determine tumors’ ability to remodel tissue: Measuring enzyme levels could help doctors select appropriate treatments September 29th, 2016

Fighting cancer with sticky nanoparticles September 27th, 2016

Gold nanoparticles conjugated quercetin inhibits epithelial-mesenchymal transition, angiogenesis and invasiveness via EGFR/VEGFR-2 mediated pathway in breast cancer September 27th, 2016

Announcements

Harris & Harris Group Notes Announcements by Its Portfolio Companies During the Third Quarter of 2016 September 30th, 2016

INVECAS to Enable ASIC Designs for Tomorrow’s Intelligent Systems on GLOBALFOUNDRIES' FDX™ Technology: INVECAS to Collaborate with GLOBALFOUNDRIES to Provide IP and End-to-End ASIC Design Services on 22FDX® and 12FDX™ Technologies September 30th, 2016

How to power up graphene implants without frying cells: New analysis finds way to safely conduct heat from graphene to biological tissues September 30th, 2016

Innovation in Nanotechnology is Focus of Symposium: Annual event brings international experts to Northwestern Oct. 6 September 29th, 2016

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







Car Brands
Buy website traffic