Nanotechnology Now







Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > 2 problems in chemical catalysis solved: University of Jyvaskyla Department of Chemistry and NanoScience Center

This image shows a novel bifunctional catalyst for the Mannich reaction.

Credit: Professor Petri Pihko
This image shows a novel bifunctional catalyst for the Mannich reaction.

Credit: Professor Petri Pihko

Abstract:
The research group of Professor Petri Pihko at the Department of Chemistry and the NanoScience Center of the University of Jyväskylä has solved two acute problems in chemical catalysis. The research has been funded by the Academy of Finland.

2 problems in chemical catalysis solved: University of Jyvaskyla Department of Chemistry and NanoScience Center

Finland | Posted on December 20th, 2012

In the first project, the researchers designed a novel intramolecularly assisted catalyst for the synthesis of beta amino acids. Previously published catalysts work only with aromatic side chains in the imines, but the new catalyst designed at Jyväskylä does not have this limitation. The new method might find uses in the synthesis of beta amino acids, which are important building blocks for chemical biology. For the understanding of the catalytic mechanism and design of the catalyst, the researchers collaborated with the group of Imre Pápai (Hungarian Academy of Sciences, computational studies) and Academy Professor Kari Rissanen (Jyväskylä, X-ray characterisation of catalysts).

In the second project, the researchers identified a completely new mechanism for the amine-catalysed Michael addition reaction between aldehydes and nitroalkenes. The mechanism has been a source of intense discussion within the scientific community, with the groups of Professor Yujiro Hayashi (Tokyo), Professor Donna Blackmond (La Jolla, USA) and Professor Dieter Seebach (ETH, Switzerland) each presenting different possible mechanisms.

The new model proposed by the Pihko and Papai groups includes a new species, a six-membered ring, as the key on-cycle intermediate that is protonated in the rate-determining step. The work is a combination of computational and experimental studies that complement each other in understanding the mechanism and demonstrate how difficult mechanistic puzzles can be solved by joining the forces of both approaches.

The research results have been published in Angewandte Chemie.

####

For more information, please click here

Contacts:
Petri Pihko

358-505-289-132

Copyright © Academy of Finland

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related Links

Download article:

Download article:

Related News Press

News and information

Nanotech-enabled moisturizer speeds healing of diabetic skin wounds: Spherical nucleic acids silence gene that interferes with wound healing April 24th, 2015

Fast and accurate 3-D imaging technique to track optically trapped particles April 24th, 2015

Pseudoparticles travel through photoactive material: KIT scientists measure important process in the conversion of light energy -- publication in Nature Communications April 24th, 2015

Scientists Use Nanoscale Building Blocks and DNA 'Glue' to Shape 3D Superlattices: New approach to designing ordered composite materials for possible energy applications April 23rd, 2015

Surface matters: Huge reduction of heat conduction observed in flat silicon channels April 23rd, 2015

Chemistry

Scientists Use Nanoscale Building Blocks and DNA 'Glue' to Shape 3D Superlattices: New approach to designing ordered composite materials for possible energy applications April 23rd, 2015

New class of 3D-printed aerogels improve energy storage April 22nd, 2015

Expanding the reach of metallic glass April 22nd, 2015

Discoveries

Nanotech-enabled moisturizer speeds healing of diabetic skin wounds: Spherical nucleic acids silence gene that interferes with wound healing April 24th, 2015

Fast and accurate 3-D imaging technique to track optically trapped particles April 24th, 2015

Pseudoparticles travel through photoactive material: KIT scientists measure important process in the conversion of light energy -- publication in Nature Communications April 24th, 2015

Surface matters: Huge reduction of heat conduction observed in flat silicon channels April 23rd, 2015

Announcements

Nanotech-enabled moisturizer speeds healing of diabetic skin wounds: Spherical nucleic acids silence gene that interferes with wound healing April 24th, 2015

Fast and accurate 3-D imaging technique to track optically trapped particles April 24th, 2015

Pseudoparticles travel through photoactive material: KIT scientists measure important process in the conversion of light energy -- publication in Nature Communications April 24th, 2015

Surface matters: Huge reduction of heat conduction observed in flat silicon channels April 23rd, 2015

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More










ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project