Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > JPK reports on the use of AFM and single-cell force spectroscopy at the Interdisciplinary Nanoscience Center at Aarhus University, Denmark

Dr Rikke Meyer of iNANO at Aarhus University, Denmark, with her JPK NanoWizard SPM system: photograph courtesy of Mikal Schlosser, Herlev, DK, www.mikals.dk.
Dr Rikke Meyer of iNANO at Aarhus University, Denmark, with her JPK NanoWizard SPM system:

photograph courtesy of Mikal Schlosser, Herlev, DK, www.mikals.dk.

Abstract:
JPK Instruments, a world-leading manufacturer of nanoanalytic instrumentation for research in life sciences and soft matter, reports on the research studies of Dr Rikke Meyer who is looking into biofilm formation from bacteria using atomic force microscopy, AFM, and single-cell force spectroscopy.

JPK reports on the use of AFM and single-cell force spectroscopy at the Interdisciplinary Nanoscience Center at Aarhus University, Denmark

Berlin, Germany | Posted on December 11th, 2012

The interdisciplinary Nanoscience Center (iNANO) was formed by various research groups at Aarhus University together with groups from the Faculty of Science at Aalborg University. iNANO comprises facilities for the synthesis of nanostructured and nanopatterned 0D (i.e. nanoparticle), 1D, 2D and 3D materials.

The group of Dr Rikke Meyer works at the interface between microbiology and nanoscience in the quest to understand how bacteria form biofilms and how this may be prevented. AFM and optical microscopy are used to visualize bacterial cells and to study the interaction forces between cells and an abiotic substrate. AFM imaging and single-cell force spectroscopy are excellent tools to visualize detailed structures on the bacterial cell surface and to study how these contribute to cell adhesion to other substrates.

The motivation for using AFM in Dr Meyer's research was firstly to obtain detailed images of bacterial cells without extensive sample preparation. Furthermore, as she is interested in the interactions between bacteria and abiotic surfaces, she and her team use AFM force spectroscopy to quantify these interaction forces. AFM is one of several techniques used in these studies. These also include brightfield microscopy, fluorescence microscopy, confocal laser scanning microscopy, scanning electron microscopy and transmission electron microscopy.

Dr Meyer comments on her research and reasons behind her choice of AFM: "The coupling with optical microscopy is no doubt the feature that was most important for me in deciding to go with an AFM from JPK. As a microbiologist, I work with very heterogenous samples and it is not feasible to use AFM imaging to locate the field of interest, as large areas of the sample are often visualized to locate a site of interest. In the combined system, we can use the optical image to locate cells of interest before engaging the AFM for imaging or other measurements."

Continuing, she said, "AFM has mostly been used to study bacterial cells that are isolated in pure culture. However, the vast majority of the bacterial species we know to date have not been isolated and can only be studied in situ. Fluorescence labeling allows a rough identification of bacteria directly in the sample and fluorescence imaging can thus be used to locate cells of interest before AFM imaging begins. The combination of AFM with optical imaging is thus particularly important for the analysis of bacteria in environmental samples."

For more details about JPK's specialist products and applications for the bio and nano sciences, please contact JPK on +49 30533112070, visit the web site: www.jpk.com or see more on Facebook: www.jpk.com/facebook.

####

About JPK Instruments (JPK)
JPK Instruments AG is a world-leading manufacturer of nanoanalytic instruments - particularly atomic force microscope (AFM) systems and optical tweezers - for a broad range of applications reaching from soft matter physics to nano-optics, from surface chemistry to cell and molecular biology. From its earliest days applying atomic force microscope (AFM) technology, JPK has recognized the opportunities provided by nanotechnology for transforming life sciences and soft matter research. This focus has driven JPK's success in uniting the worlds of nanotechnology tools and life science applications by offering cutting-edge technology and unique applications expertise. Headquartered in Berlin and with direct operations in Dresden, Cambridge (UK), Singapore, Tokyo and Paris (France), JPK maintains a global network of distributors and support centers and provides on the spot applications and service support to an ever-growing community of researchers.

For more information, please click here

Contacts:
JPK Instruments AG
Bouchéstrasse 12
Haus 2, Aufgang C
Berlin 12435
Germany
T +49 30533112070
F +49 30 5331 22555
www.jpk.com


Talking Science Limited
39 de Bohun Court
Saffron Walden
Essex CB10 2BA
United Kingdom
T +44(0)1799 521881
M +44(0)7843 012997
www.talking-science.com

Copyright © JPK Instruments (JPK)

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Sopping up proteins with thermosponges: Researchers develop novel nanoparticle platform that proves effective in delivering protein-based drugs October 22nd, 2014

Brookhaven Lab Launches Computational Science Initiative:Leveraging computational science expertise and investments across the Laboratory to tackle "big data" challenges October 22nd, 2014

Bipolar Disorder Discovery at the Nano Level: Tiny structures found in brain synapses help scientists better understand disorder October 22nd, 2014

NIST offers electronics industry 2 ways to snoop on self-organizing molecules October 22nd, 2014

Journal Nanotechnology Progress International (JONPI), 2014, Volume 5, Issue 1, pp 1-24 October 22nd, 2014

Imaging

NIST offers electronics industry 2 ways to snoop on self-organizing molecules October 22nd, 2014

Special UO microscope captures defects in nanotubes: University of Oregon chemists provide a detailed view of traps that disrupt energy flow, possibly pointing toward improved charge-carrying devices October 21st, 2014

Academic/Education

First Canada Excellence Research Chair gets $10 million from the federal government for oilsands research at the University of Calgary: Federal government announces prestigious research chair to study improving oil production efficiency October 19th, 2014

Raytheon, UMass Lowell open on-campus research institute: Industry leader’s researchers to collaborate with faculty, students to move key technologies forward through first-of-its-kind partnership October 11th, 2014

SUNY Colleges of Nanoscale Science and Engineering and National Institute for Occupational Safety and Health Announce Expanded Partnership October 2nd, 2014

Yale University and Leica Microsystems Partner to Establish Microscopy Center of Excellence: Yale Welcomes Scientists to Participate in Core Facility Opening and Super- Resolution Workshops October 20 Through 31, 2014 September 30th, 2014

Nanomedicine

Sopping up proteins with thermosponges: Researchers develop novel nanoparticle platform that proves effective in delivering protein-based drugs October 22nd, 2014

Bipolar Disorder Discovery at the Nano Level: Tiny structures found in brain synapses help scientists better understand disorder October 22nd, 2014

Journal Nanotechnology Progress International (JONPI), 2014, Volume 5, Issue 1, pp 1-24 October 22nd, 2014

TARA Biosystems and Harris & Harris Group Form Company to Improve Safety and Efficacy of New Therapies October 22nd, 2014

Announcements

NanoTechnology for Defense (NT4D) October 22nd, 2014

Mechanism behind nature's sparkles revealed October 22nd, 2014

TARA Biosystems and Harris & Harris Group Form Company to Improve Safety and Efficacy of New Therapies October 22nd, 2014

Researchers patent a nanofluid that improves heat conductivity October 22nd, 2014

Tools

NIST offers electronics industry 2 ways to snoop on self-organizing molecules October 22nd, 2014

Special UO microscope captures defects in nanotubes: University of Oregon chemists provide a detailed view of traps that disrupt energy flow, possibly pointing toward improved charge-carrying devices October 21st, 2014

Super stable garnet ceramics may be ideal for high-energy lithium batteries October 21st, 2014

Detecting Cancer Earlier is Goal of Rutgers-Developed Medical Imaging Technology: Rare earth nanocrystals and infrared light can reveal small cancerous tumors and cardiovascular lesions October 21st, 2014

Nanobiotechnology

Mechanism behind nature's sparkles revealed October 22nd, 2014

‘Designer’ nanodevice could improve treatment options for cancer sufferers October 22nd, 2014

Crystallizing the DNA nanotechnology dream: Scientists have designed the first large DNA crystals with precisely prescribed depths and complex 3D features, which could create revolutionary nanodevices October 20th, 2014

Scientists Map Key Moment in Assembly of DNA-Splitting Molecular Machine: Crucial steps and surprising structures revealed in the genesis of the enzyme that divides the DNA double helix during cell replication October 15th, 2014

New-Contracts/Sales/Customers

Dyesol Signs Letter of Intent with Tata Steel October 13th, 2014

HZO Teams With Deutsche Telekom to Unveil the Waterproof Tolino Vision 2 eReader: The New HZO Protected eReader Ushers in a New Era of Waterproof Electronics, Providing a Seamless User Experience Without the Risk of Using Port Doors and Mechanical Seals October 10th, 2014

Fullerex: Talga Resources Joins INSCX™ Exchange September 4th, 2014

Global Energy Systems Signs Master Sales Agreement with China Aviation Supplies Group September 4th, 2014

NanoNews-Digest
The latest news from around the world, FREE





  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE