- About Us
- Career Center
- Nano-Social Network
- Nano Consulting
- My Account
|Dr Rikke Meyer of iNANO at Aarhus University, Denmark, with her JPK NanoWizard SPM system: |
photograph courtesy of Mikal Schlosser, Herlev, DK, www.mikals.dk.
JPK Instruments, a world-leading manufacturer of nanoanalytic instrumentation for research in life sciences and soft matter, reports on the research studies of Dr Rikke Meyer who is looking into biofilm formation from bacteria using atomic force microscopy, AFM, and single-cell force spectroscopy.
The interdisciplinary Nanoscience Center (iNANO) was formed by various research groups at Aarhus University together with groups from the Faculty of Science at Aalborg University. iNANO comprises facilities for the synthesis of nanostructured and nanopatterned 0D (i.e. nanoparticle), 1D, 2D and 3D materials.
The group of Dr Rikke Meyer works at the interface between microbiology and nanoscience in the quest to understand how bacteria form biofilms and how this may be prevented. AFM and optical microscopy are used to visualize bacterial cells and to study the interaction forces between cells and an abiotic substrate. AFM imaging and single-cell force spectroscopy are excellent tools to visualize detailed structures on the bacterial cell surface and to study how these contribute to cell adhesion to other substrates.
The motivation for using AFM in Dr Meyer's research was firstly to obtain detailed images of bacterial cells without extensive sample preparation. Furthermore, as she is interested in the interactions between bacteria and abiotic surfaces, she and her team use AFM force spectroscopy to quantify these interaction forces. AFM is one of several techniques used in these studies. These also include brightfield microscopy, fluorescence microscopy, confocal laser scanning microscopy, scanning electron microscopy and transmission electron microscopy.
Dr Meyer comments on her research and reasons behind her choice of AFM: "The coupling with optical microscopy is no doubt the feature that was most important for me in deciding to go with an AFM from JPK. As a microbiologist, I work with very heterogenous samples and it is not feasible to use AFM imaging to locate the field of interest, as large areas of the sample are often visualized to locate a site of interest. In the combined system, we can use the optical image to locate cells of interest before engaging the AFM for imaging or other measurements."
Continuing, she said, "AFM has mostly been used to study bacterial cells that are isolated in pure culture. However, the vast majority of the bacterial species we know to date have not been isolated and can only be studied in situ. Fluorescence labeling allows a rough identification of bacteria directly in the sample and fluorescence imaging can thus be used to locate cells of interest before AFM imaging begins. The combination of AFM with optical imaging is thus particularly important for the analysis of bacteria in environmental samples."
For more details about JPK's specialist products and applications for the bio and nano sciences, please contact JPK on +49 30533112070, visit the web site: www.jpk.com or see more on Facebook: www.jpk.com/facebook.
About JPK Instruments (JPK)
JPK Instruments AG is a world-leading manufacturer of nanoanalytic instruments - particularly atomic force microscope (AFM) systems and optical tweezers - for a broad range of applications reaching from soft matter physics to nano-optics, from surface chemistry to cell and molecular biology. From its earliest days applying atomic force microscope (AFM) technology, JPK has recognized the opportunities provided by nanotechnology for transforming life sciences and soft matter research. This focus has driven JPK's success in uniting the worlds of nanotechnology tools and life science applications by offering cutting-edge technology and unique applications expertise. Headquartered in Berlin and with direct operations in Dresden, Cambridge (UK), Singapore, Tokyo and Paris (France), JPK maintains a global network of distributors and support centers and provides on the spot applications and service support to an ever-growing community of researchers.
For more information, please click here
JPK Instruments AG
Haus 2, Aufgang C
T +49 30533112070
F +49 30 5331 22555
Talking Science Limited
39 de Bohun Court
Essex CB10 2BA
T +44(0)1799 521881
M +44(0)7843 012997
Copyright © JPK Instruments (JPK)If you have a comment, please Contact us.
Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.
|Related News Press|
News and information
Quantum networks: Back and forth are not equal distances! July 28th, 2015
Stretching the limits on conducting wires July 25th, 2015
Nanopaper as an optical sensing platform July 23rd, 2015
Spintronics: Molecules stabilizing magnetism: Organic molecules fixing the magnetic orientation of a cobalt surface/ building block for a compact and low-cost storage technology/ publication in Nature Materials July 25th, 2015
Biophotonics - Global Strategic Business Report 2015 July 21st, 2015
Rare form: Novel structures built from DNA emerge July 20th, 2015
Dais Analytic's Business Affiliate in China Announces Ten-Year Strategic Energy Efficiency Business Arrangement With COFCO: Dais Beijing to Perform Feasibility Study on Over 80 Buildings to Improve Efficiencies as Part of Overall Hotel Energy-Savings Project July 23rd, 2015