Nanotechnology Now

Our NanoNews Digest Sponsors


Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Naturally occurring fungus nanoparticles have potential for cancer therapy

Abstract:
Naturally occurring nanoparticles have drawn significant interests from scientific communities, due to their unique properties and promising biocompatibility. Given the earth's rich biological diversity, it is reasonable to believe that these nanoparticles, with various forms and functions, may be produced from a variety of organisms, ranging from microbes to metazoans.

Naturally occurring fungus nanoparticles have potential for cancer therapy

Germany | Posted on December 7th, 2012

Dr. Yongzhong Wang and co-workers in Dr. Mingjun Zhang's group at The University of Tennessee, Knoxville, have worked on naturally occurring nanoparticles using various microbial cultures, and discovered a novel cancer therapeutic from a surprising source: the carnivorous fungus Arthrobotrys oligospora.

This specialized fungus forms adhesive traps for capturing and digesting unlucky nematodes that cross its path. While studying the trapping mechanism, Dr. Zhang's group created a sitting drop system to culture A. oligospora, and noticed that nanocomposites were secreted from the fungal hyphae and traps. Upon further study using advanced microscopic techniques, they discovered that these nanocomposites contained highly uniform nanoparticles. Knowing the importance of nanoparticles in cancer therapy, Dr. Zhang's group investigated the potential capability of the fungal nanoparticles as an immunostimulatory and antitumor agent. Surprisingly, the fungal nanoparticles were able to stimulate TNF-α secretion from macrophages, and kill cancer cells in vitro.

This study by Dr. Zhang's group has proposed a new approach for producing novel organic nanoparticles from microorganisms under controllable conditions. It may open up a new avenue for controlling the synthesis of organic nanoparticles using synthetic biology. This exciting discovery is the first step forward in the development of natural nanoparticle-based therapeutics for cancer treatment, and demonstrates the importance of looking to nature for innovation in disease treatment.

####

For more information, please click here

Copyright © Wiley-VCH Materials Science Journals

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related Links

Link to the original paper on Wiley Online Library:

Related News Press

News and information

How cancer cells spread and squeeze through tiny blood vessels (video) June 30th, 2016

Oxford Instruments and Dresden High Magnetic Field Laboratory collaborate to develop HTS magnet technology components for high field superconducting magnet systems June 29th, 2016

Texas A&M Chemist Says Trapped Electrons To Blame For Lack Of Battery Efficiency: Forget mousetraps — today’s scientists will get the cheese if they manage to build a better battery June 28th, 2016

Building a smart cardiac patch: 'Bionic' cardiac patch could one day monitor and respond to cardiac problems June 28th, 2016

Nanomedicine

How cancer cells spread and squeeze through tiny blood vessels (video) June 30th, 2016

Building a smart cardiac patch: 'Bionic' cardiac patch could one day monitor and respond to cardiac problems June 28th, 2016

Nanoscientists develop the 'ultimate discovery tool': Rapid discovery power is similar to what gene chips offer biology June 25th, 2016

Nanotechnology and math deliver two-in-one punch for cancer therapy resistance June 24th, 2016

Discoveries

How cancer cells spread and squeeze through tiny blood vessels (video) June 30th, 2016

Texas A&M Chemist Says Trapped Electrons To Blame For Lack Of Battery Efficiency: Forget mousetraps — today’s scientists will get the cheese if they manage to build a better battery June 28th, 2016

Building a smart cardiac patch: 'Bionic' cardiac patch could one day monitor and respond to cardiac problems June 28th, 2016

New, better way to build circuits for world's first useful quantum computers June 28th, 2016

Announcements

How cancer cells spread and squeeze through tiny blood vessels (video) June 30th, 2016

Oxford Instruments and Dresden High Magnetic Field Laboratory collaborate to develop HTS magnet technology components for high field superconducting magnet systems June 29th, 2016

Texas A&M Chemist Says Trapped Electrons To Blame For Lack Of Battery Efficiency: Forget mousetraps — today’s scientists will get the cheese if they manage to build a better battery June 28th, 2016

Building a smart cardiac patch: 'Bionic' cardiac patch could one day monitor and respond to cardiac problems June 28th, 2016

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







Car Brands
Buy website traffic