Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > Naturally occurring fungus nanoparticles have potential for cancer therapy

Abstract:
Naturally occurring nanoparticles have drawn significant interests from scientific communities, due to their unique properties and promising biocompatibility. Given the earth's rich biological diversity, it is reasonable to believe that these nanoparticles, with various forms and functions, may be produced from a variety of organisms, ranging from microbes to metazoans.

Naturally occurring fungus nanoparticles have potential for cancer therapy

Germany | Posted on December 7th, 2012

Dr. Yongzhong Wang and co-workers in Dr. Mingjun Zhang's group at The University of Tennessee, Knoxville, have worked on naturally occurring nanoparticles using various microbial cultures, and discovered a novel cancer therapeutic from a surprising source: the carnivorous fungus Arthrobotrys oligospora.

This specialized fungus forms adhesive traps for capturing and digesting unlucky nematodes that cross its path. While studying the trapping mechanism, Dr. Zhang's group created a sitting drop system to culture A. oligospora, and noticed that nanocomposites were secreted from the fungal hyphae and traps. Upon further study using advanced microscopic techniques, they discovered that these nanocomposites contained highly uniform nanoparticles. Knowing the importance of nanoparticles in cancer therapy, Dr. Zhang's group investigated the potential capability of the fungal nanoparticles as an immunostimulatory and antitumor agent. Surprisingly, the fungal nanoparticles were able to stimulate TNF-α secretion from macrophages, and kill cancer cells in vitro.

This study by Dr. Zhang's group has proposed a new approach for producing novel organic nanoparticles from microorganisms under controllable conditions. It may open up a new avenue for controlling the synthesis of organic nanoparticles using synthetic biology. This exciting discovery is the first step forward in the development of natural nanoparticle-based therapeutics for cancer treatment, and demonstrates the importance of looking to nature for innovation in disease treatment.

####

For more information, please click here

Copyright © Wiley-VCH Materials Science Journals

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related Links

Link to the original paper on Wiley Online Library:

Related News Press

News and information

Oxford Instruments announces Dr Kate Ross as winner of the 2018 Lee Osheroff Richardson Science Prize for North and South America February 20th, 2018

Computers aid discovery of new, inexpensive material to make LEDs with high color quality February 20th, 2018

Unconventional superconductor may be used to create quantum computers of the future: They have probably succeeded in creating a topological superconductor February 19th, 2018

Photonic chip guides single photons, even when there are bends in the road February 16th, 2018

Nanomedicine

Arrowhead Receives Regulatory Clearance to Begin Phase 1/2 Study of ARO-HBV for Treatment of Hepatitis B February 15th, 2018

Arrowhead Pharmaceuticals Receives Orphan Drug Designation for ARO-AAT February 15th, 2018

'Living bandages': NUST MISIS scientists develop biocompatible anti-burn nanofibers February 15th, 2018

Understanding brain functions using upconversion nanoparticles: Researchers can now send light deep into the brain to study neural activities February 14th, 2018

Discoveries

Computers aid discovery of new, inexpensive material to make LEDs with high color quality February 20th, 2018

Unconventional superconductor may be used to create quantum computers of the future: They have probably succeeded in creating a topological superconductor February 19th, 2018

Photonic chip guides single photons, even when there are bends in the road February 16th, 2018

'Living bandages': NUST MISIS scientists develop biocompatible anti-burn nanofibers February 15th, 2018

Announcements

Oxford Instruments announces Dr Kate Ross as winner of the 2018 Lee Osheroff Richardson Science Prize for North and South America February 20th, 2018

Computers aid discovery of new, inexpensive material to make LEDs with high color quality February 20th, 2018

Unconventional superconductor may be used to create quantum computers of the future: They have probably succeeded in creating a topological superconductor February 19th, 2018

Photonic chip guides single photons, even when there are bends in the road February 16th, 2018

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project