- About Us
- Career Center
- Nano-Social Network
- Nano Consulting
- My Account
Ivan M. Kempson et al. have investigated the intravenous delivery and excretion of polyethylene glycol (PEG)-coated gold nanoparticles (GNPs) in the whiskers and at the pilosebaceous unit in a mouse model. The use of X-ray fluorescence allowed visualisation of this deposition and, after 14 days, gold bands could be visualised in the hairs, the pharmacokinetic profiles of which indicated the blood concentration kinetics.
This deposition of nanoparticles was found to take place intermittently during this 14 day period, so demonstrating the prolonged mobility of these nanoparticles within the body. Furthermore, confocal microscopy was used to make a 3D reconstruction of nanoparticle distribution leading to identification of nanoparticle aggregates within the medullary canal.
These results are of interest in understanding the fate and excretion of nanoparticles from the body. Also, due to the successful elucidation of kinetic information from hair samples, this illustrates the potential for testing the nanoparticle load in the body via hair sampling as oppose to blood sampling.
For more information, please click here
Copyright © Wiley-VCH Materials Science JournalsIf you have a comment, please Contact us.
Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.
|Related News Press|
News and information
Two UCSB Professors Receive Early Career Research Awards: The Department of Energy’s award for young scientists acknowledges UC Santa Barbara’s standing as a top tier research institution May 29th, 2015
New chip makes testing for antibiotic-resistant bacteria faster, easier: Researchers at the University of Toronto design diagnostic chip to reduce testing time from days to one hour, allowing doctors to pick the right antibiotic the first time May 28th, 2015
Arrowhead to Present at Jefferies 2015 Healthcare Conference May 27th, 2015
Nanotechnology identifies brain tumor types through MRI 'virtual biopsy' in animal studies: If results are confirmed in humans, tumor cells could someday be diagnosed by MRI imaging and treated with tumor-specific IV injections; new NIH grant will fund future study May 27th, 2015
New technique speeds nanoMRI imaging: Multiplexing technique for nanoscale magnetic resonance imaging developed by researchers in Switzerland cuts normal scan time from two weeks to two days May 28th, 2015
Cotton fibres instead of carbon nanotubes May 9th, 2015