Home > Press > Tracking Gold Nanoparticles in the Body: Where Do They Go?
 |
Abstract:
Ivan M. Kempson et al. have investigated the intravenous delivery and excretion of polyethylene glycol (PEG)-coated gold nanoparticles (GNPs) in the whiskers and at the pilosebaceous unit in a mouse model. The use of X-ray fluorescence allowed visualisation of this deposition and, after 14 days, gold bands could be visualised in the hairs, the pharmacokinetic profiles of which indicated the blood concentration kinetics.
Tracking Gold Nanoparticles in the Body: Where Do They Go?
Germany | Posted on November 19th, 2012This deposition of nanoparticles was found to take place intermittently during this 14 day period, so demonstrating the prolonged mobility of these nanoparticles within the body. Furthermore, confocal microscopy was used to make a 3D reconstruction of nanoparticle distribution leading to identification of nanoparticle aggregates within the medullary canal.
These results are of interest in understanding the fate and excretion of nanoparticles from the body. Also, due to the successful elucidation of kinetic information from hair samples, this illustrates the potential for testing the nanoparticle load in the body via hair sampling as oppose to blood sampling.
####
For more information, please click here
Copyright © Wiley-VCH Materials Science Journals
If you have a comment, please Contact us.Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.
Bookmark:
| Related Links |
Link to the original paper on Wiley Online Library:
| Related News Press |
News and information
Simulating magnetization in a Heisenberg quantum spin chain April 5th, 2024
NRL charters Navy’s quantum inertial navigation path to reduce drift April 5th, 2024
Discovery points path to flash-like memory for storing qubits: Rice find could hasten development of nonvolatile quantum memory April 5th, 2024
Nanomedicine
New micromaterial releases nanoparticles that selectively destroy cancer cells April 5th, 2024
Good as gold - improving infectious disease testing with gold nanoparticles April 5th, 2024
Researchers develop artificial building blocks of life March 8th, 2024
Discoveries
Chemical reactions can scramble quantum information as well as black holes April 5th, 2024
New micromaterial releases nanoparticles that selectively destroy cancer cells April 5th, 2024
Utilizing palladium for addressing contact issues of buried oxide thin film transistors April 5th, 2024
Announcements
NRL charters Navy’s quantum inertial navigation path to reduce drift April 5th, 2024
Discovery points path to flash-like memory for storing qubits: Rice find could hasten development of nonvolatile quantum memory April 5th, 2024
Safety-Nanoparticles/Risk management
Tests find no free-standing nanotubes released from tire tread wear September 8th, 2023
Billions of nanoplastics released when microwaving baby food containers: Exposure to plastic particles kills up to 75% of cultured kidney cells July 21st, 2023
 |
||
 |
||
| The latest news from around the world, FREE | ||
 |
||
|
|
||
| Premium Products | ||
 |
||
|
Only the news you want to read!
Learn More |
||
 |
||
|
Full-service, expert consulting
Learn More |
||
|
|
||