Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > Research Shows Graphene Nanopores Can Be Controlled: Less Costly Ways of Sequencing DNA Could Open New Possibilities for Disease Prevention

These are transmission electron microscope images of a nanopore in graphene. The original pore on the left grows considerably under the influence of the electron beam. The image on the right is the pore after four minutes at 800 °C.  Pores either shrink or grow depending on the temperature and electron beam irradiation.
These are transmission electron microscope images of a nanopore in graphene. The original pore on the left grows considerably under the influence of the electron beam. The image on the right is the pore after four minutes at 800 °C. Pores either shrink or grow depending on the temperature and electron beam irradiation.

Abstract:
Engineers at The University of Texas at Dallas have used advanced techniques to make the material graphene small enough to read DNA.

Research Shows Graphene Nanopores Can Be Controlled: Less Costly Ways of Sequencing DNA Could Open New Possibilities for Disease Prevention

Dallas, TX | Posted on October 3rd, 2012

Shrinking the size of a graphene pore to less than one nanometer - small enough to thread a DNA strand - opens the possibility of using graphene as a low-cost tool to sequence DNA.

"Sequencing DNA at a very cheap cost would enable scientists and doctors to better predict and diagnose disease, and also tailor a drug to an individual's genetic code," said Dr. Moon Kim, professor of materials science and engineering. He was senior author of an article depicted on the cover of the September print edition of Carbon.

The first reading, or sequencing, of human DNA by the international scientific research group known as the Human Genome Project cost about $2.7 billion. Engineers have been researching alternative nanomaterials materials that can thread DNA strands to reduce the cost to less than $1,000 per person.

It was demonstrated in 2004 that graphite could be changed into a sheet of bonded carbon atoms called graphene, which is believed to be the strongest material ever measured. Because graphene is thin and strong, researchers have searched for ways to control its pore size. They have not had much success. A nanoscale sensor made of graphene could be integrated with existing silicon-based electronics that are very advanced and yet cheap, to reduce costs.

In this study, Kim and his team manipulated the size of the nanopore by using an electron beam from an advanced electron microscope and in-situ heating up to 1200 degree Celsius temperature.

"This is the first time that the size of the graphene nanopore has been controlled, especially shrinking it," said Kim. "We used high temperature heating and electron beam simultaneously, one technique without the other doesn't work."

Now that researchers know the pore size can be controlled, the next step in their research will be to build a prototype device.

"If we could sequence DNA cheaply, the possibilities for disease prevention, diagnosis and treatment would be limitless," Kim said. "Controlling graphene puts us one step closer to making this happen."

Other UT Dallas researchers from the Erik Jonsson School of Engineering and Computer Science involved in this project are Dr. Ning Lu, research scientist in materials science and engineering; Dr. Jinguo Wang, associate EM Facility Director; and Dr. Herman Carlo Floresca, postdoctoral research fellow in materials science and engineering.

The study was funded by the Southwest Academy of Nanoelectronics, Air Force Office of Scientific Research and the World Class University Program.

####

For more information, please click here

Contacts:
LaKisha Ladson

972-883-4183
or
Office of Media Relations
UT Dallas, (972) 883-2155

Copyright © University of Texas at Dallas

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Video captures bubble-blowing battery in action: Researchers propose how bubbles form, could lead to smaller lithium-air batteries April 26th, 2017

New Product Nanoparticle preparation from Intertronics with new Thinky NP-100 Nano Pulveriser April 26th, 2017

California Research Alliance by BASF establishes more than 25 research projects in three years April 26th, 2017

Affordable STM32 Cloud-Connectable Kit from STMicroelectronics Puts More Features On-Board for Fast and Flexible IoT-Device Development April 26th, 2017

Graphene/ Graphite

Graphene holds up under high pressure: Used in filtration membranes, ultrathin material could help make desalination more productive April 24th, 2017

Two-dimensional melting of hard spheres experimentally unravelled after 60 years: First definitive experimental evidence of two-dimensional melting of hard spheres April 21st, 2017

Researchers “iron out” graphene’s wrinkles: New technique produces highly conductive graphene wafers April 3rd, 2017

New ultrafast flexible and transparent memory devices could herald new era of electronics April 1st, 2017

Govt.-Legislation/Regulation/Funding/Policy

Graphene holds up under high pressure: Used in filtration membranes, ultrathin material could help make desalination more productive April 24th, 2017

Nanoparticle vaccine shows potential as immunotherapy to fight multiple cancer types April 24th, 2017

NanoMONITOR shares its latest developments concerning the NanoMONITOR Software and the Monitoring stations April 21st, 2017

Better living through pressure: Functional nanomaterials made easy April 19th, 2017

Nanomedicine

New Product Nanoparticle preparation from Intertronics with new Thinky NP-100 Nano Pulveriser April 26th, 2017

Nanoparticle vaccine shows potential as immunotherapy to fight multiple cancer types April 24th, 2017

Arrowhead Presents ARC-520 and ARC-521 Clinical Data at The International Liver Congress(TM) April 20th, 2017

Nano-SPEARs gently measure electrical signals in small animals: Rice University's tiny needles simplify data gathering to probe diseases, test drugs April 17th, 2017

Discoveries

Geoffrey Beach: Drawn to explore magnetism: Materials researcher is working on the magnetic memory of the future April 25th, 2017

Using light to propel water : With new method, MIT engineers can control and separate fluids on a surface using only visible light April 25th, 2017

Graphene holds up under high pressure: Used in filtration membranes, ultrathin material could help make desalination more productive April 24th, 2017

Nanoparticle vaccine shows potential as immunotherapy to fight multiple cancer types April 24th, 2017

Announcements

Video captures bubble-blowing battery in action: Researchers propose how bubbles form, could lead to smaller lithium-air batteries April 26th, 2017

New Product Nanoparticle preparation from Intertronics with new Thinky NP-100 Nano Pulveriser April 26th, 2017

California Research Alliance by BASF establishes more than 25 research projects in three years April 26th, 2017

Affordable STM32 Cloud-Connectable Kit from STMicroelectronics Puts More Features On-Board for Fast and Flexible IoT-Device Development April 26th, 2017

Military

Nano-SPEARs gently measure electrical signals in small animals: Rice University's tiny needles simplify data gathering to probe diseases, test drugs April 17th, 2017

New technology could offer cheaper, faster food testing: Specialized droplets interact with bacteria and can be analyzed using a smartphone April 7th, 2017

Teri Odom and Richard Van Duyne Honored by Department of Defense: Each will receive $3 million over five years to conduct high-risk, high-payoff research March 31st, 2017

NIST physicists show ion pairs perform enhanced 'spooky action' March 30th, 2017

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project