Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > Malvern’s new Zetasizer Nano ZSP delivers fast, high sensitivity protein characterization for multiple applications

The new Zetasizer Nano ZSP from Malvern Instruments delivers unique protein characterization capabilities in a single, easy to use instrument.
The new Zetasizer Nano ZSP from Malvern Instruments delivers unique protein characterization capabilities in a single, easy to use instrument.

Abstract:
The new Zetasizer Nano ZSP from Malvern Instruments is a high specification dynamic light scattering system that delivers unique protein characterization capabilities in a single, easy to use instrument. This top-of-the-range addition to Malvern's established Zetasizer Nano family enables highly sensitive measurement of zeta potential, for rapid, reliable measurement of the electrophoretic mobility of proteins, and subsequent calculation of the key parameter of protein charge. Measuring protein mobility (or zeta potential) by dynamic light scattering is faster and more convenient than conventional methods such as capillary electrophoresis and iso-electric focussing. Furthermore, the Zetasizer Nano ZSP requires only 20 microliters of sample and measures at concentrations down to 1 mg/mL.

Malvern’s new Zetasizer Nano ZSP delivers fast, high sensitivity protein characterization for multiple applications

Malvern, UK | Posted on September 27th, 2012

Key to achieving superior protein mobility measurements are a highly sensitive measurement system, the ability to protect the sample from aggregation, and flexible software that presents data in an immediately usable format. The Zetasizer Nano ZSP has the count rate sensitivity needed to easily measure weakly scattering samples such as proteins, and the instrument's protein mobility measurement process is designed to maximize measurement quality using three specific features. Firstly, by combining size and zeta potential measurements the Zetasizer software can ensure that no aggregates are forming during the measurement, and warn the user is this does start to occur. Secondly, mobility measurements are performed in groups of sub-runs to allow extended periods of cooling, reducing the possibility of aggregation through heating. And thirdly, automatic optimization of measurement settings minimizes denaturation and aggregation during mobility measurements.

A suite of protein calculators has been added as part of the software developments that accompany the launch of the Zetasizer Nano ZSP, which are included with the instrument as standard. These include a dynamic DLS Debye Plot which allows calculation of the DLS interaction parameter, especially useful in protein formulation for biological therapeutics. There is also the ability to calculate protein charge from protein mobility, F(ka) from the Henry equation, interparticle distance, and thermodynamic diameter (virial radius).

Find out more at www.malvern.com/nano-zsp

Malvern, Malvern Instruments an Zetasizer are registered trademarks of Malvern Instruments Ltd

####

About Malvern Instruments
Malvern Instruments is a market leader in measuring performance controlling material properties. These include particle size, particle shape, zeta potential, molecular weight, size and conformation, rheological properties and chemical identification. Malvern delivers the systems, support and expertise that ensure the analytical integrity and productivity needed to drive research, development and manufacturing.

Malvern’s measurement solutions for scientists, technologists and engineers advance continually through customer collaboration. Complementary materials characterization systems deliver inter-related measurements that reflect the complexities of particulates and disperse systems, nanomaterials and macromolecules. Combining intelligently implemented technologies with in-depth industry applications knowledge and support, Malvern provides customers with the competitive advantage they demand.

Headquartered in Malvern, UK, Malvern Instruments has subsidiary organizations in all major European markets, North America, China, Japan and Korea, a joint venture in India, a global distributor network and applications laboratories around the world.

Facebook: MalvernInstruments
Blog: www.materials-talks.com
Youtube: malverninstruments
Linked-In: malvern-instruments
Twitter: malvern_news

For more information, please click here

Contacts:
For press information, please contact:

Trish Appleton
Kapler Communications
Phoenix House, Phoenix Park
Eaton Socon, Cambridgeshire, PE19 8EP, UK
Tel: +44 (0)1480 471059
Fax: +44 (0)1480 471069


USA contact:

Marisa Fraser
Malvern Instruments Inc.
117 Flanders Road
Westborough, MA 01581-1042 USA
Tel: +1 508 768 6400
Fax: +1 508 768 6403


Please send sales enquiries to:

Alison Vines
Malvern Instruments Ltd
Enigma Business Park, Grovewood Road
Malvern, Worcestershire WR14 1XZ UK
Tel: +44 (0) 1684 892456
Fax: +44 (0) 1684 892789

Copyright © Malvern Instruments

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Freeze-dried foam soaks up carbon dioxide: Rice University scientists lead effort to make novel 3-D material August 16th, 2017

Gold shines through properties of nano biosensors: Researchers discover that fluorescence in ligand-protected gold nanoclusters is an intrinsic property of the gold particles themselves August 16th, 2017

Two Scientists Receive Grants to Develop New Materials: Chad Mirkin and Monica Olvera de la Cruz recognized by Sherman Fairchild Foundation August 16th, 2017

Scientists from the University of Manchester and Diamond Light Source work with Deben to develop and test a new compression stage to study irradiated graphite at elevated temperatures August 15th, 2017

Imaging

Industry’s First Dedicated Cryo-DualBeam System Automates Preparation of Frozen, Biological Samples: New Thermo Scientific Aquilos FIB/SEM protects sample integrity and enhances productivity for cryo-electron tomography workflow August 8th, 2017

Thermo Fisher Scientific Advances Cryo-EM Leadership to Drive Structural Biology Discoveries: New Thermo Scientific Krios G3i raises bar for performance, automation and time-to-results Breakthrough Thermo Scientific Glacios provides a cryo-EM entry path for a broader range of res August 8th, 2017

New Quattro Field Emission ESEM Emphasizes Versatility and Ease of Use: Thermo Scientific Quattro ESEM allows materials science researchers to study nanoscale structure in almost any material under a range of environmental conditions August 8th, 2017

Thermo Fisher Scientific’s New Talos F200i S/TEM Delivers Flexible, High-Performance Imaging: New compact S/TEM can be configured to meet specific imaging and analytical requirements for materials characterization in research laboratories August 8th, 2017

Announcements

Freeze-dried foam soaks up carbon dioxide: Rice University scientists lead effort to make novel 3-D material August 16th, 2017

Gold shines through properties of nano biosensors: Researchers discover that fluorescence in ligand-protected gold nanoclusters is an intrinsic property of the gold particles themselves August 16th, 2017

Two Scientists Receive Grants to Develop New Materials: Chad Mirkin and Monica Olvera de la Cruz recognized by Sherman Fairchild Foundation August 16th, 2017

Scientists from the University of Manchester and Diamond Light Source work with Deben to develop and test a new compression stage to study irradiated graphite at elevated temperatures August 15th, 2017

Tools

Scientists from the University of Manchester and Diamond Light Source work with Deben to develop and test a new compression stage to study irradiated graphite at elevated temperatures August 15th, 2017

FRITSCH • Milling and Sizing! Innovations at POWTECH 2017 - Hall 2 • Stand 227 August 9th, 2017

New Quattro Field Emission ESEM Emphasizes Versatility and Ease of Use: Thermo Scientific Quattro ESEM allows materials science researchers to study nanoscale structure in almost any material under a range of environmental conditions August 8th, 2017

Thermo Fisher Scientific’s New Talos F200i S/TEM Delivers Flexible, High-Performance Imaging: New compact S/TEM can be configured to meet specific imaging and analytical requirements for materials characterization in research laboratories August 8th, 2017

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project