Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > The Laser Beam as a “3D Painter”

A complex 3D pattern created using photografting – an Echinodermania.
A complex 3D pattern created using photografting – an Echinodermania.

Abstract:
With laser beams, molecules can be fixed at exactly the right position in a three dimensional material. A new method developed at the Vienna University of Technology can be used to grow biological tissue or to create micro sensors.

The Laser Beam as a “3D Painter”

Germany | Posted on August 25th, 2012

With laser beams, molecules can be fixed at exactly the right position in a three dimensional material. A new method developed at the Vienna University of Technology can be used to grow biological tissue or to create micro sensors.

There are many ways to create three dimensional objects on a micrometer scale. But how can the chemical properties of a material be tuned to micrometer precision? Scientists at the Vienna University of Technology have developed a method to attach molecules at exactly the right place. When biological tissue is grown, this method can allow the positioning of chemical signals, telling living cells where to attach. The new technique also holds promise for sensor technology: A tiny three dimensional "lab on a chip" could be created, in which accurately positioned molecules react with substances from the environment.

Materials Science and Chemistry

"3D-photografting" is the name of the new method. Two research teams from the Vienna University of Technology collaborated closely to develop it: Professor Jürgen Stampfl's materials science team and Professor Robert Liska's research group for macromolecular chemistry.

Both research groups have already attracted considerable attention in the past, developing new kinds of 3D-printers. However, for the applications on which the scientists are working on now, 3D-printing would not have been useful: "Putting together a material from tiny building blocks with different chemical properties would be extremely complicated", says Aleksandr Ovsianikov. "That is why we start from a three dimensional scaffold and then attach the desired molecules at exactly the right positions."

Molecules in the Hydrogel - Locked into Position by the Laser

The scientists start with a so-called hydrogel - a material made of macromolecules, arranged in a loose meshwork. Between those molecules, large pores remain, through which other molecules or even cells can migrate.

Specially selected molecules are introduced into the hydrogel meshwork, then certain points are irradiated with a laser beam. At the positions where the focused laser beam is most intense, a photochemically labile bond is broken. That way, highly reactive intermediates are created which locally attach to the hydrogel very quickly. The precision depends on the laser's lens system, at the Vienna University of Technology a resolution of 4 µm could be obtained. "Much like an artist, placing colors at certain points of the canvas, we can place molecules in the hydrogel - but in three dimensions and with high precision", says Aleksandr Ovsianikov.

Chemical Signals for Cells

This method can be used to artificially grow biological tissue. Like a climbing plant clinging to a rack, cells need some scaffold at which they attach. In a natural tissue, the extracellular matrix does the trick by using specific amino acid sequences to signal the cells, where they are supposed to grow.

In the lab, scientists are trying to use similar chemical signals. In various experiments, cell attachment could be guided on two dimensional surfaces, but in order to grow larger tissues with a specific inner structure (such as capillaries), a truly three dimensional technique is required.

Micro Sensors Detect Molecules

Depending on the application, different molecules can be used. 3D photografting is not only useful for bio-engineering but also for other fields, such as photovoltaics or sensor technology. In a very small space, molecules can be positioned which attach to specific chemical substances and allow their detection. A microscopic three-dimensional "lab on a chip" becomes possible.

####

For more information, please click here

Copyright © Wiley-VCH Materials Science Journals

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related Links

Link to the original paper on Wiley Online Library:

Related News Press

News and information

Efficiency of Nanodrug Containing Antibiotics in Treatment of Infectious Diseases Evaluated August 31st, 2015

Seeing quantum motion August 30th, 2015

Artificial leaf harnesses sunlight for efficient fuel production August 30th, 2015

Researchers use DNA 'clews' to shuttle CRISPR-Cas9 gene-editing tool into cells August 30th, 2015

Chemistry

A new technique to make drugs more soluble August 28th, 2015

Nanocatalysts improve processes for the petrochemical industry August 28th, 2015

Researchers combine disciplines, computational programs to determine atomic structure August 26th, 2015

Laser-burned graphene gains metallic powers: Rice University scientists find possible replacement for platinum as catalyst August 20th, 2015

Electrospray solves longstanding problem in Langmuir-Blodgett assembly: The electrospray spreads water-soluble solvents on water while minimizing mixing August 20th, 2015

3D printing

These microscopic fish are 3-D-printed to do more than swim: Researchers demonstrate a novel method to build microscopic robots with complex shapes and functionalities August 26th, 2015

Nanomedicine

Efficiency of Nanodrug Containing Antibiotics in Treatment of Infectious Diseases Evaluated August 31st, 2015

Researchers use DNA 'clews' to shuttle CRISPR-Cas9 gene-editing tool into cells August 30th, 2015

Iranian Scientists Use Artemisia Annua Plant to Produce Breast Cancer Drugs August 29th, 2015

Small but heading for the big time: Nanobiotix half year results for the six months ended 30 June 2015, in line with expectations: Major clinical achievements and corporate developments August 28th, 2015

Sensors

Successful boron-doping of graphene nanoribbon August 27th, 2015

Nanotechnology that will impact the Security & Defense sectors to be discussed at NanoSD2015 conference August 25th, 2015

High Precision, High Stability XYZ Microscope Stages, with Capacitive Feedback August 18th, 2015

Setting ground rules for nanotechnology research: Two new projects set the stage for nanotechnology research to move into Big Data August 18th, 2015

Discoveries

Efficiency of Nanodrug Containing Antibiotics in Treatment of Infectious Diseases Evaluated August 31st, 2015

Seeing quantum motion August 30th, 2015

Artificial leaf harnesses sunlight for efficient fuel production August 30th, 2015

Researchers use DNA 'clews' to shuttle CRISPR-Cas9 gene-editing tool into cells August 30th, 2015

Materials/Metamaterials

Draw out of the predicted interatomic force August 30th, 2015

Nanocatalysts improve processes for the petrochemical industry August 28th, 2015

Successful boron-doping of graphene nanoribbon August 27th, 2015

Developing Component Scale Composites Using Nanocarbons August 26th, 2015

Announcements

Efficiency of Nanodrug Containing Antibiotics in Treatment of Infectious Diseases Evaluated August 31st, 2015

Seeing quantum motion August 30th, 2015

Artificial leaf harnesses sunlight for efficient fuel production August 30th, 2015

Researchers use DNA 'clews' to shuttle CRISPR-Cas9 gene-editing tool into cells August 30th, 2015

Nanobiotechnology

Researchers use DNA 'clews' to shuttle CRISPR-Cas9 gene-editing tool into cells August 30th, 2015

Small but heading for the big time: Nanobiotix half year results for the six months ended 30 June 2015, in line with expectations: Major clinical achievements and corporate developments August 28th, 2015

Nanotechnology that will impact the Security & Defense sectors to be discussed at NanoSD2015 conference August 25th, 2015

Louisiana Tech University researchers discover synthesis of a new nanomaterial: Interdisciplinary team creates biocomposite for first time using physiological conditions August 24th, 2015

Photonics/Optics/Lasers

Glitter from silver lights up Alzheimer's dark secrets August 25th, 2015

Quantum diffraction at a breath of nothing: Physicists build stable diffraction structure in atomically thin graphene August 25th, 2015

Nanotechnology that will impact the Security & Defense sectors to be discussed at NanoSD2015 conference August 25th, 2015

A little light interaction leaves quantum physicists beaming August 25th, 2015

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







Car Brands
Buy website traffic