Nanotechnology Now

Our NanoNews Digest Sponsors
Heifer International



Home > Press > Finding the nano-needle in the haystack

Abstract:
Norwegian researchers are among the first in the world to use radioactivity to trace nanoparticles in experimental animals and soil. Their findings have made it easier to identify any negative environmental impact of nanoparticles, which are found in an increasing number of products.

Finding the nano-needle in the haystack

Oslo, Norway | Posted on August 17th, 2012

Nanotechnology can be used to improve the properties of commercial products, to kill bacteria, fight odours and more. But what happens when these products are discarded and these incomprehensibly small particles are released into the environment? Can these same qualities that kill bacteria in athletic garments, washing machines and refrigerators have an unintended detrimental impact on health and the environment as well?

Millionths of a millimeter

Nanoparticle use is posing new questions to researchers studying environmentally hazardous substances. The size of nanoparticles is actually measured in millionths of a millimetre. They are far too small for the examination methods used with common chemicals.

The first challenge is to find a way to track where these particles end up. Unless they can be located it will not be possible to determine much about their impact. So what needs to be done to track them down?

"Simply put, it's easier to find a needle in a haystack when that needle is radioactive," says Dr Deborah H. Oughton. Dr Oughton is a professor at the Norwegian University of Life Sciences (UMB), specialising in nuclear chemistry. As part of a joint research project involving UMB, the Norwegian Institute for Water Research (NIVA), Bioforsk and international research partners, she has headed the effort to develop methods for tracing nanoparticles by rendering them radioactive. The project is part of the Research Council of Norway's programme on Norwegian Environmental Research towards 2015 (MILJO2015).

Difficult to discover

"Nanoparticles are so miniscule that they are hard to find using methods common for other environmentally hazardous substances. Researchers looking for potential effects of nanoparticle contamination often resort to the use of unrealistically high concentrations of particles in their experiments," Dr Oughton states.

But there are several drawbacks to such an approach. First of all, the properties of particles change when concentrations become so dense. Secondly, such methods reveal very little about the spread patterns of the nanoparticles, break down over time or the capacity of nanoparticles to accumulate in concentrations presumed to normally occur in nature.

"This is why we wanted to test if it was possible to track nanoparticles using radioactivity," Dr Oughton explains.

Radioactivity as a marker

Dr Oughton has her background in nuclear chemistry and took the idea that radioactivity could be used as a marker from this and several other fields. Related methods are already in use for studies of radioactive environmental contamination as well as in medical diagnostics.

"We looked at methods used in other fields and worked our way towards something which would work for nanoparticles. The idea is that when particles are radioactive, they can be traced. Our trials demonstrate that we can obtain a large amount of new and valuable information using this method even with a very low concentration of particles," says Dr Oughton.

Highly dangerous to fish

Dr Oughton and colleague Dr Erik Joner of Bioforsk, among others, came up with a method in which earthworms were fed horse dung containing radioactive nanoparticles of silver, cobalt and uranium. Subsequently, they were able to study the uptake and accumulation of the nanoparticles by observing how the radioactivity was distributed and then comparing their observations with physiological findings. In other experiments from the same project, fish were exposed to various concentrations of nanoparticles.

"One of our discoveries showed that nanoparticles can accumulate in different parts of an organism. In salmon, we witnessed that certain nanoparticles affected gill function and had a severely toxic effect. The presence of surprisingly low concentrations of certain types of nanosilvers led to gill failure and resulting death of the fish."

The study used lake water in order to optimise the relevance of the findings. The water in many lakes in Norway is relatively low in calcium. We found that this increases the amount of time nanoparticles stay in the water, says Dr Oughton.

The finding that nanoparticles may have detrimental effects on fish gives cause for concern as the presence of nanosilver has previously been detected in waste water from sewage purification plants. Nanosilver is also widely used in clothing, and studies show that washing clothes releases nanosilver into the water drainage. Nanosilver is even used in washing machines themselves in many countries, although this is not allowed in Norway.

Nanoparticles can release ions over long periods

The researchers also found out new information about the long-term behaviour of nanoparticles in soil.

"Nanoparticles break down over time through the slow release of ions. For some nanoparticles, these ions are the agents responsible for toxic effects on organisms. This gradual leakage of ions means that free nanoparticles continue to pollute the environment over a long period of time," Dr Oughton states.

Some more toxic than others

The researchers also discovered differences among nanoparticles. Nanosilver was the most toxic of the group.

"Some types of nanosilver had a greater toxic effect than others. It is important for governments and industry to learn more about the risks involved with the various types of nanoparticles. Our research findings, along with other research on the environmental impact of nanoparticles, mean that we will soon know enough to know how to regulate use in order to prevent damage to the environment," says Dr Oughton.

Growing market, budding research activity

The use of nanoparticles has increased greatly in recent years. Areas of application include cosmetics, clothing, toys and food. The use of nanosilver as an anti-bacterial coating in refrigerators, sports clothing and bandages is among the most common uses.

A great deal of research on the effects of nanosilver and other nanoparticles on health and the environment is being conducted both in Norway and other countries.

"The results from our research project have been published internationally and have attracted interest from many countries. We are currently collaborating with researchers in France, among others, to develop measurement methods based on radioactive markers. At the same time, research institutions in Norway and the EU have also indicated their interest. The work is being continued under several projects funded by the Research Council of Norway and European research institutions," Dr Oughton points out.

####

About The Research Council of Norway
The Research Council of Norway plays a vital role in developing and implementing the country''s national research strategy. It acts as:

* a government adviser, identifying present and future needs for knowledge and research;

* a funding agency for independent research programmes and projects, strategic programmes at research institutes, and Norwegian participation in international research programmes;

* a co-ordinator, initiating networks and promoting co-operation between R&D institutions, ministries, business and industry, public agencies and enterprises, other sources of funding, and users of research.

The Executive Board of the Research Council of Norway is responsible for the Council''s policy at the national level. Six research boards, one for each research division, submit annual strategic plans and budgets to the main Executive Board for final approval.

Important research priorities according to the Research Council are:

* basic research

* marine research

* information and communication technology

* health research

* energy and climate research

* biotechnology

* petroleum research

* material science

Approximately one third of Norway''s public sector research investment is channelled through the Research Council. The remainder is transferred directly from the ministries to the relevant research institutions. In 1999, Norway spent a total of NOK 20 billion on R&D, of which public sector allocations accounted for roughly NOK 8.5 billion. In 2003 the Research Council of Norway has a budget of NOK 4,4 billion.

For more information, please click here

Contacts:
Thomas Keilman
+47 22 03 70 00

Copyright © AlphaGalileo

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Researchers develop artificial building blocks of life March 8th, 2024

How surface roughness influences the adhesion of soft materials: Research team discovers universal mechanism that leads to adhesion hysteresis in soft materials March 8th, 2024

Two-dimensional bimetallic selenium-containing metal-organic frameworks and their calcinated derivatives as electrocatalysts for overall water splitting March 8th, 2024

Curcumin nanoemulsion is tested for treatment of intestinal inflammation: A formulation developed by Brazilian researchers proved effective in tests involving mice March 8th, 2024

Govt.-Legislation/Regulation/Funding/Policy

What heat can tell us about battery chemistry: using the Peltier effect to study lithium-ion cells March 8th, 2024

Researchers’ approach may protect quantum computers from attacks March 8th, 2024

The Access to Advanced Health Institute receives up to $12.7 million to develop novel nanoalum adjuvant formulation for better protection against tuberculosis and pandemic influenza March 8th, 2024

Optically trapped quantum droplets of light can bind together to form macroscopic complexes March 8th, 2024

Discoveries

What heat can tell us about battery chemistry: using the Peltier effect to study lithium-ion cells March 8th, 2024

Researchers’ approach may protect quantum computers from attacks March 8th, 2024

High-tech 'paint' could spare patients repeated surgeries March 8th, 2024

Nanoscale CL thermometry with lanthanide-doped heavy-metal oxide in TEM March 8th, 2024

Announcements

What heat can tell us about battery chemistry: using the Peltier effect to study lithium-ion cells March 8th, 2024

Curcumin nanoemulsion is tested for treatment of intestinal inflammation: A formulation developed by Brazilian researchers proved effective in tests involving mice March 8th, 2024

The Access to Advanced Health Institute receives up to $12.7 million to develop novel nanoalum adjuvant formulation for better protection against tuberculosis and pandemic influenza March 8th, 2024

Nanoscale CL thermometry with lanthanide-doped heavy-metal oxide in TEM March 8th, 2024

Environment

$900,000 awarded to optimize graphene energy harvesting devices: The WoodNext Foundation's commitment to U of A physicist Paul Thibado will be used to develop sensor systems compatible with six different power sources January 12th, 2024

Catalytic combo converts CO2 to solid carbon nanofibers: Tandem electrocatalytic-thermocatalytic conversion could help offset emissions of potent greenhouse gas by locking carbon away in a useful material January 12th, 2024

New catalyst could dramatically cut methane pollution from millions of engines: Researchers demonstrate a way to remove the potent greenhouse gas from the exhaust of engines that burn natural gas. July 21st, 2023

Billions of nanoplastics released when microwaving baby food containers: Exposure to plastic particles kills up to 75% of cultured kidney cells July 21st, 2023

Safety-Nanoparticles/Risk management

First human trial shows ‘wonder’ material can be developed safely: A revolutionary nanomaterial with huge potential to tackle multiple global challenges could be developed further without acute risk to human health, research suggests February 16th, 2024

New research may make future design of nanotechnology safer with fewer side effects: Study shows a promising strategy to reduce adverse reactions to nanoparticles by using complement inhibitors October 6th, 2023

Tests find no free-standing nanotubes released from tire tread wear September 8th, 2023

Billions of nanoplastics released when microwaving baby food containers: Exposure to plastic particles kills up to 75% of cultured kidney cells July 21st, 2023

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project