Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > Antibacterial Nanoparticles Prove More Efficient than Gentamicin in Fighting Infections

Abstract:
A multidisciplinary and multinational research group consisted of researchers from the University of Tehran, Iran, University of Mons, Belgium, University of Groningen and University of Twente, the Netherlands, carefully investigated the antibacterial behavior of magnetic iron oxide nanoparticles and demonstrated their efficacy as biocompatible antibacterial agents.

Antibacterial Nanoparticles Prove More Efficient than Gentamicin in Fighting Infections

Tehran, Iran | Posted on August 7th, 2012

In order to overcome the shortcomings of the commonly prescribed antibiotics in the treatment of infections caused by implanted biomaterials, the researchers devised an external magnetic field to guide the mentioned nanoparticles towards the grown bacterial colonies through a targeted drug delivery approach. By doing so, a multiple-fold higher antibacterial activity, compared with gentamicin, was achieved.

"As the initial part of our research, we carried out a feasibility study on the use of SPOINs (superparamagnetic iron oxide nanoparticles) as bactericide agents. The idea was triggered by the fact that most of metal nanoparticles exhibit antibacterial characteristics. Although their applicability is hindered by their potential toxicities, SPOINs are found to kill only the bacteria and being harmless to human body cells," Dr. Shahriar Sharifi, member of the research group, explained.

"Bearing the special magnetic properties of the SPOINs in mind, we tried to direct these nanoparticles to the locations of the bacterial colonies by exerting an external magnetic field. In this way, we came up with considerably increased and deeper penetration of the nanoparticles into the formed biofilms. These diffused SPOINs later generate reactive oxygen species (ROS), thanks to their nanometric dimensions as small as 5 nm, which damage the bacterial cell walls resulting in their death." Dr. Sharifi said, explaining about the mechanism of antibacterial activity of the SPIONs.

The results of this research work have been published in detail in Acta Biomaterialia.

####

For more information, please click here

Copyright © Fars News Agency

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Heating quantum matter: A novel view on topology: Physicists demonstrate how heating up a quantum system can be used as a universal probe for exotic states of matter August 22nd, 2017

A Tougher Tooth: A new dental restoration composite developed by UCSB scientists proves more durable than the conventional material August 22nd, 2017

Nagoya physicists resolve long-standing mystery of structure-less transition: Nagoya University-led team of physicists use a synchrotron radiation X-ray source to probe a so-called 'structure-less' transition and develop a new understanding of molecular conductors August 21st, 2017

Tokai University research: Nanomaterial wrap for improved tissue imaging August 21st, 2017

Nanomedicine

Tokai University research: Nanomaterial wrap for improved tissue imaging August 21st, 2017

Gold nanostars and immunotherapy vaccinate mice against cancer: New treatment cures, vaccinates mouse in small proof-of-concept study August 18th, 2017

Freeze-dried foam soaks up carbon dioxide: Rice University scientists lead effort to make novel 3-D material August 16th, 2017

Gold shines through properties of nano biosensors: Researchers discover that fluorescence in ligand-protected gold nanoclusters is an intrinsic property of the gold particles themselves August 16th, 2017

Discoveries

Heating quantum matter: A novel view on topology: Physicists demonstrate how heating up a quantum system can be used as a universal probe for exotic states of matter August 22nd, 2017

A Tougher Tooth: A new dental restoration composite developed by UCSB scientists proves more durable than the conventional material August 22nd, 2017

Nagoya physicists resolve long-standing mystery of structure-less transition: Nagoya University-led team of physicists use a synchrotron radiation X-ray source to probe a so-called 'structure-less' transition and develop a new understanding of molecular conductors August 21st, 2017

Tokai University research: Nanomaterial wrap for improved tissue imaging August 21st, 2017

Announcements

Heating quantum matter: A novel view on topology: Physicists demonstrate how heating up a quantum system can be used as a universal probe for exotic states of matter August 22nd, 2017

A Tougher Tooth: A new dental restoration composite developed by UCSB scientists proves more durable than the conventional material August 22nd, 2017

Nagoya physicists resolve long-standing mystery of structure-less transition: Nagoya University-led team of physicists use a synchrotron radiation X-ray source to probe a so-called 'structure-less' transition and develop a new understanding of molecular conductors August 21st, 2017

Tokai University research: Nanomaterial wrap for improved tissue imaging August 21st, 2017

Nanobiotechnology

Tokai University research: Nanomaterial wrap for improved tissue imaging August 21st, 2017

Gold nanostars and immunotherapy vaccinate mice against cancer: New treatment cures, vaccinates mouse in small proof-of-concept study August 18th, 2017

Freeze-dried foam soaks up carbon dioxide: Rice University scientists lead effort to make novel 3-D material August 16th, 2017

Gold shines through properties of nano biosensors: Researchers discover that fluorescence in ligand-protected gold nanoclusters is an intrinsic property of the gold particles themselves August 16th, 2017

Research partnerships

A Tougher Tooth: A new dental restoration composite developed by UCSB scientists proves more durable than the conventional material August 22nd, 2017

Researchers printed graphene-like materials with inkjet August 17th, 2017

Freeze-dried foam soaks up carbon dioxide: Rice University scientists lead effort to make novel 3-D material August 16th, 2017

2-faced 2-D material is a first at Rice: Rice University materials scientists create flat sandwich of sulfur, molybdenum and selenium August 14th, 2017

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project