Nanotechnology Now

Our NanoNews Digest Sponsors







Heifer International

Wikipedia Affiliate Button


Home > Press > Antibacterial Nanoparticles Prove More Efficient than Gentamicin in Fighting Infections

Abstract:
A multidisciplinary and multinational research group consisted of researchers from the University of Tehran, Iran, University of Mons, Belgium, University of Groningen and University of Twente, the Netherlands, carefully investigated the antibacterial behavior of magnetic iron oxide nanoparticles and demonstrated their efficacy as biocompatible antibacterial agents.

Antibacterial Nanoparticles Prove More Efficient than Gentamicin in Fighting Infections

Tehran, Iran | Posted on August 7th, 2012

In order to overcome the shortcomings of the commonly prescribed antibiotics in the treatment of infections caused by implanted biomaterials, the researchers devised an external magnetic field to guide the mentioned nanoparticles towards the grown bacterial colonies through a targeted drug delivery approach. By doing so, a multiple-fold higher antibacterial activity, compared with gentamicin, was achieved.

"As the initial part of our research, we carried out a feasibility study on the use of SPOINs (superparamagnetic iron oxide nanoparticles) as bactericide agents. The idea was triggered by the fact that most of metal nanoparticles exhibit antibacterial characteristics. Although their applicability is hindered by their potential toxicities, SPOINs are found to kill only the bacteria and being harmless to human body cells," Dr. Shahriar Sharifi, member of the research group, explained.

"Bearing the special magnetic properties of the SPOINs in mind, we tried to direct these nanoparticles to the locations of the bacterial colonies by exerting an external magnetic field. In this way, we came up with considerably increased and deeper penetration of the nanoparticles into the formed biofilms. These diffused SPOINs later generate reactive oxygen species (ROS), thanks to their nanometric dimensions as small as 5 nm, which damage the bacterial cell walls resulting in their death." Dr. Sharifi said, explaining about the mechanism of antibacterial activity of the SPIONs.

The results of this research work have been published in detail in Acta Biomaterialia.

####

For more information, please click here

Copyright © Fars News Agency

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

JPK reports on single molecule research at IISER Pune in India using AFM and CellHesion techniques May 21st, 2013

Imec and GLOBALFOUNDRIES collaborate to advance high-density memory technology: STT-MRAM offers enhanced performance and scalability for embedded and standalone applications May 21st, 2013

International survey supports need for built-in water protection on smartphones and tablets May 21st, 2013

Rice unveils method for tailoring optical processors: Arranging nanoparticles in geometric patterns allows for control of light with light May 21st, 2013

Nanomedicine

How Gold Nanoparticles Can Help Fight Ovarian Cancer May 21st, 2013

MU Researchers Develop Radioactive Nanoparticles that Target Cancer Cells: This is an early step toward developing therapies for metastasized cancers, MU scientist says May 21st, 2013

Nanoparticle Delivers Large Protein Complex to Cancer Cell Nucleus May 20th, 2013

Elsevier Business Intelligence (EBI) to Host 'IN3 Medical Device 360 Boston,' June 24-26, 2013 May 20th, 2013

Discoveries

How Gold Nanoparticles Can Help Fight Ovarian Cancer May 21st, 2013

MU Researchers Develop Radioactive Nanoparticles that Target Cancer Cells: This is an early step toward developing therapies for metastasized cancers, MU scientist says May 21st, 2013

Study Led by George Washington University Professor Provides Better Understanding of Water’s Freezing Behavior at Nanoscale May 21st, 2013

Rice unveils method for tailoring optical processors: Arranging nanoparticles in geometric patterns allows for control of light with light May 21st, 2013

Announcements

JPK reports on single molecule research at IISER Pune in India using AFM and CellHesion techniques May 21st, 2013

Imec and GLOBALFOUNDRIES collaborate to advance high-density memory technology: STT-MRAM offers enhanced performance and scalability for embedded and standalone applications May 21st, 2013

International survey supports need for built-in water protection on smartphones and tablets May 21st, 2013

Rice unveils method for tailoring optical processors: Arranging nanoparticles in geometric patterns allows for control of light with light May 21st, 2013

Nanobiotechnology

Researchers Perform Fastest Measurements Ever Made of Ion Channel Proteins May 20th, 2013

Artificial Forest for Solar Water-Splitting: Berkeley Lab Researchers Report First Fully Integrated Artificial Photosynthesis Nanosystem May 17th, 2013

Glowing Plant Kickstarter Project Retains Digital Marketing Agency, Command Partners: Glowing Plant brings on top Charlotte-based digital marketing firm to assist in crowdfunding campaign May 16th, 2013

DNA-Guided Assembly Yields Novel Ribbon-Like Nanostructures: Approach could be useful in fabricating new kinds of materials with engineered properties May 16th, 2013

Research partnerships

Imec and GLOBALFOUNDRIES collaborate to advance high-density memory technology: STT-MRAM offers enhanced performance and scalability for embedded and standalone applications May 21st, 2013

Kinks and curves at the nanoscale: New research shows 'perfect twin boundaries' are not so perfect May 20th, 2013

Advancements and developments of solid-state nanopores sensors May 16th, 2013

Imec and Renesas collaborate on ultra-low power short range radios: Collaboration will develop robust wireless solutions for future electronics May 16th, 2013

NanoNews-Digest
The latest news from around the world, FREE





  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More












ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project








abbigliamento uomo
Computer Accessories
© Copyright 1999-2013 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE