Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > Novel Nano Bio-Sensor Able to Detect Lactate Contents

Abstract:
Iranian researchers at the University of Kurdistan produced a novel and efficient bio-sensor for the detection of minute lactate contents in biological samples, using nanocomposites.

Novel Nano Bio-Sensor Able to Detect Lactate Contents

Tehran, Iran | Posted on July 10th, 2012

Their proposed bio-sensor involves a nanocomposite, consisting of functionalized carbon nanotubes and magnetic iron oxide nanoparticles, used in a process which led to the production of a sensitive electro-catalytic system.

Dehydrogenase enzymes form the most extensive category of known enzymes which includes more than 300 different types. Lactate dehygroenases (LDHs) are a group of enzymes found in the cytoplasm of almost all body tissues. The LDH content in the body increases in case of various diseases. Thus, LDH measurement has been proved to serve as a tool for preliminary diagnosis of renal infraction, renal cell carcinoma, skeletal muscle disease, etc.

In this context, the measurement of very low substrate concentrations of the mentioned enzyme (lactate) is of practical importance. The proposed "functionalized carbon nanotubes - Fe3O4 magnetic nanoparticles" nanocomposite enables the oxidative elecrocatalysis of NADH at very low potentials. Finally, the covalent bonding of the NAD+ cofactor and the lactate dehygroenase enzyme upon the synthesized nanocomposite led to the production of a fully integrated bio-sensor for lactate analysis.

"The catalytic property of the invented nanocomposite at very low potentials is due the synergism arising from the combination of the two involved nanostructures (functionalized carbon nanotubes and Fe3O4 magnetic nanoparticles). In addition, another advantage of our proposed system lies in the biocompatibility of the nanocomposite which is in favor of protecting the lactate dehygroenase," Dr. Salimi, a member of the research group, explained.

An elaborate report on this research work has been published in Biosensors and Bioelectronics.

####

For more information, please click here

Copyright © Fars News Agency

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Scientists announce the quest for high-index materials: All-dielectric nanophotonics: The quest for better materials and fabrication techniques July 22nd, 2017

Pulses of electrons manipulate nanomagnets and store information: Scientists use electron pulses to create and manipulate nanoscale magnetic excitations that can store data July 21st, 2017

The first light atomic nucleus with a second face July 20th, 2017

Semiliquid chains pulled out of a sea of microparticles July 20th, 2017

Nanomedicine

Scientists announce the quest for high-index materials: All-dielectric nanophotonics: The quest for better materials and fabrication techniques July 22nd, 2017

Probiotics: Novel biosynthetic tool to develop metallic nanoparticles: This research article by Dr. Nida Akhtar et al has been published in Recent Patents on Drug Delivery & Formulation, Volume 11, Issue 1, 2017 July 20th, 2017

Semiliquid chains pulled out of a sea of microparticles July 20th, 2017

'Upconverted' light has a bright future: Rice University professor developing plasmon-powered devices for medicine, security, solar cells July 17th, 2017

Sensors

Giant enhancement of electromagnetic waves revealed within small dielectric particles: Scientists have done for the first time direct measurements of giant electromagnetic fields July 8th, 2017

Bosch announces high-performance MEMS acceleration sensors for wearables June 27th, 2017

Letiís Autonomous-Vehicle System Embedded in Infineonís AURIX Platform: Letiís Low-Power, Multi-Sensor System that Transforms Distance Data into Clear Information About the Driving Environment Will Be Demonstrated at ITS Meeting in Strasbourg, June 19-22 June 20th, 2017

New diode features optically controlled capacitance: Israeli researchers have developed a new optically tunable capacitor with embedded metal nanoparticles, creating a metal-insulator-semiconductor diode that is tunable by illumination. June 8th, 2017

Discoveries

Scientists announce the quest for high-index materials: All-dielectric nanophotonics: The quest for better materials and fabrication techniques July 22nd, 2017

Pulses of electrons manipulate nanomagnets and store information: Scientists use electron pulses to create and manipulate nanoscale magnetic excitations that can store data July 21st, 2017

The first light atomic nucleus with a second face July 20th, 2017

Semiliquid chains pulled out of a sea of microparticles July 20th, 2017

Announcements

Scientists announce the quest for high-index materials: All-dielectric nanophotonics: The quest for better materials and fabrication techniques July 22nd, 2017

Pulses of electrons manipulate nanomagnets and store information: Scientists use electron pulses to create and manipulate nanoscale magnetic excitations that can store data July 21st, 2017

The first light atomic nucleus with a second face July 20th, 2017

Semiliquid chains pulled out of a sea of microparticles July 20th, 2017

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project