Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > Novel Nano Bio-Sensor Able to Detect Lactate Contents

Abstract:
Iranian researchers at the University of Kurdistan produced a novel and efficient bio-sensor for the detection of minute lactate contents in biological samples, using nanocomposites.

Novel Nano Bio-Sensor Able to Detect Lactate Contents

Tehran, Iran | Posted on July 10th, 2012

Their proposed bio-sensor involves a nanocomposite, consisting of functionalized carbon nanotubes and magnetic iron oxide nanoparticles, used in a process which led to the production of a sensitive electro-catalytic system.

Dehydrogenase enzymes form the most extensive category of known enzymes which includes more than 300 different types. Lactate dehygroenases (LDHs) are a group of enzymes found in the cytoplasm of almost all body tissues. The LDH content in the body increases in case of various diseases. Thus, LDH measurement has been proved to serve as a tool for preliminary diagnosis of renal infraction, renal cell carcinoma, skeletal muscle disease, etc.

In this context, the measurement of very low substrate concentrations of the mentioned enzyme (lactate) is of practical importance. The proposed "functionalized carbon nanotubes - Fe3O4 magnetic nanoparticles" nanocomposite enables the oxidative elecrocatalysis of NADH at very low potentials. Finally, the covalent bonding of the NAD+ cofactor and the lactate dehygroenase enzyme upon the synthesized nanocomposite led to the production of a fully integrated bio-sensor for lactate analysis.

"The catalytic property of the invented nanocomposite at very low potentials is due the synergism arising from the combination of the two involved nanostructures (functionalized carbon nanotubes and Fe3O4 magnetic nanoparticles). In addition, another advantage of our proposed system lies in the biocompatibility of the nanocomposite which is in favor of protecting the lactate dehygroenase," Dr. Salimi, a member of the research group, explained.

An elaborate report on this research work has been published in Biosensors and Bioelectronics.

####

For more information, please click here

Copyright © Fars News Agency

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Searching for errors in the quantum world September 21st, 2018

Viral RNA sensing: Optical detection of picomolar concentrations of RNA using switches in plasmonic chirality September 21st, 2018

UT engineers develop first method for controlling nanomotors: Breakthrough for nanotechnology as UT engineers develop first method for switching the mechanical motion of nanomotors September 21st, 2018

Nanobiotix: Update on Head and Neck Phase I/II Trial with NBTXR3 and Other program data presented at ImmunoRad 2018 September 20th, 2018

Nanomedicine

Viral RNA sensing: Optical detection of picomolar concentrations of RNA using switches in plasmonic chirality September 21st, 2018

UT engineers develop first method for controlling nanomotors: Breakthrough for nanotechnology as UT engineers develop first method for switching the mechanical motion of nanomotors September 21st, 2018

Nanobiotix: Update on Head and Neck Phase I/II Trial with NBTXR3 and Other program data presented at ImmunoRad 2018 September 20th, 2018

NUS researchers invent new test kit for quick, accurate and low-cost screening of diseases: Test results are denoted by a color change and could be further analyzed by a smartphone app, making it attractive as a point-of-care diagnostic device September 19th, 2018

Sensors

UT engineers develop first method for controlling nanomotors: Breakthrough for nanotechnology as UT engineers develop first method for switching the mechanical motion of nanomotors September 21st, 2018

Leti Announces EU Project to Develop Powerful, Inexpensive Sensors with Photonic Integrated Circuits: REDFINCH Members Initially Targeting Applications for Gas Detection and Analysis For Refineries & Petrochemical Industry and Protein Analysis for Dairy Industry September 19th, 2018

Rice U. lab probes molecular limit of plasmonics: Optical effect detailed in organic molecules with fewer than 50 atoms September 5th, 2018

Measuring the nanoworld September 4th, 2018

Discoveries

Searching for errors in the quantum world September 21st, 2018

Viral RNA sensing: Optical detection of picomolar concentrations of RNA using switches in plasmonic chirality September 21st, 2018

UT engineers develop first method for controlling nanomotors: Breakthrough for nanotechnology as UT engineers develop first method for switching the mechanical motion of nanomotors September 21st, 2018

NUS researchers invent new test kit for quick, accurate and low-cost screening of diseases: Test results are denoted by a color change and could be further analyzed by a smartphone app, making it attractive as a point-of-care diagnostic device September 19th, 2018

Announcements

Searching for errors in the quantum world September 21st, 2018

Viral RNA sensing: Optical detection of picomolar concentrations of RNA using switches in plasmonic chirality September 21st, 2018

UT engineers develop first method for controlling nanomotors: Breakthrough for nanotechnology as UT engineers develop first method for switching the mechanical motion of nanomotors September 21st, 2018

Nanobiotix: Update on Head and Neck Phase I/II Trial with NBTXR3 and Other program data presented at ImmunoRad 2018 September 20th, 2018

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project