Nanotechnology Now







Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Novel Nano Bio-Sensor Able to Detect Lactate Contents

Abstract:
Iranian researchers at the University of Kurdistan produced a novel and efficient bio-sensor for the detection of minute lactate contents in biological samples, using nanocomposites.

Novel Nano Bio-Sensor Able to Detect Lactate Contents

Tehran, Iran | Posted on July 10th, 2012

Their proposed bio-sensor involves a nanocomposite, consisting of functionalized carbon nanotubes and magnetic iron oxide nanoparticles, used in a process which led to the production of a sensitive electro-catalytic system.

Dehydrogenase enzymes form the most extensive category of known enzymes which includes more than 300 different types. Lactate dehygroenases (LDHs) are a group of enzymes found in the cytoplasm of almost all body tissues. The LDH content in the body increases in case of various diseases. Thus, LDH measurement has been proved to serve as a tool for preliminary diagnosis of renal infraction, renal cell carcinoma, skeletal muscle disease, etc.

In this context, the measurement of very low substrate concentrations of the mentioned enzyme (lactate) is of practical importance. The proposed "functionalized carbon nanotubes - Fe3O4 magnetic nanoparticles" nanocomposite enables the oxidative elecrocatalysis of NADH at very low potentials. Finally, the covalent bonding of the NAD+ cofactor and the lactate dehygroenase enzyme upon the synthesized nanocomposite led to the production of a fully integrated bio-sensor for lactate analysis.

"The catalytic property of the invented nanocomposite at very low potentials is due the synergism arising from the combination of the two involved nanostructures (functionalized carbon nanotubes and Fe3O4 magnetic nanoparticles). In addition, another advantage of our proposed system lies in the biocompatibility of the nanocomposite which is in favor of protecting the lactate dehygroenase," Dr. Salimi, a member of the research group, explained.

An elaborate report on this research work has been published in Biosensors and Bioelectronics.

####

For more information, please click here

Copyright © Fars News Agency

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Toyocolor to Launch New Carbon Nanotube Materials at nano tech 2015 January 24th, 2015

NANOPOSTER 2015 - 5th Virtual Nanotechnology Conference - call for abstracts January 24th, 2015

Nanosensor Used for Simultaneous Determination of Effective Tea Components January 24th, 2015

The latest fashion: Graphene edges can be tailor-made: Rice University theory shows it should be possible to tune material's properties January 24th, 2015

Nanomedicine

Teijin to Participate in Nano Tech 2015 January 22nd, 2015

2nd International Conference on Infectious Diseases & Nanomedicine (December 15-18, 2015, Kathmandu, NEPAL) January 22nd, 2015

Anti-microbial coatings with a long-term effect for surfaces presentation at nano tech 2015 in Japan January 21st, 2015

A spoonful of sugar in silver nanoparticles to regulate their toxicity January 21st, 2015

Sensors

Nanosensor Used for Simultaneous Determination of Effective Tea Components January 24th, 2015

Iranian Scientists Produce Graphene-Based Oxygen Sensor January 23rd, 2015

Graphene brings quantum effects to electronic circuits January 22nd, 2015

New method to generate arbitrary optical pulses January 21st, 2015

Discoveries

Nanosensor Used for Simultaneous Determination of Effective Tea Components January 24th, 2015

The latest fashion: Graphene edges can be tailor-made: Rice University theory shows it should be possible to tune material's properties January 24th, 2015

Iranian Scientists Produce Graphene-Based Oxygen Sensor January 23rd, 2015

Silver nanowires demonstrate unexpected self-healing mechanism: The material has potential for flexible electronics January 23rd, 2015

Announcements

Toyocolor to Launch New Carbon Nanotube Materials at nano tech 2015 January 24th, 2015

NANOPOSTER 2015 - 5th Virtual Nanotechnology Conference - call for abstracts January 24th, 2015

Nanosensor Used for Simultaneous Determination of Effective Tea Components January 24th, 2015

The latest fashion: Graphene edges can be tailor-made: Rice University theory shows it should be possible to tune material's properties January 24th, 2015

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More










ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2015 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE