Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > Novel Nano Bio-Sensor Able to Detect Lactate Contents

Abstract:
Iranian researchers at the University of Kurdistan produced a novel and efficient bio-sensor for the detection of minute lactate contents in biological samples, using nanocomposites.

Novel Nano Bio-Sensor Able to Detect Lactate Contents

Tehran, Iran | Posted on July 10th, 2012

Their proposed bio-sensor involves a nanocomposite, consisting of functionalized carbon nanotubes and magnetic iron oxide nanoparticles, used in a process which led to the production of a sensitive electro-catalytic system.

Dehydrogenase enzymes form the most extensive category of known enzymes which includes more than 300 different types. Lactate dehygroenases (LDHs) are a group of enzymes found in the cytoplasm of almost all body tissues. The LDH content in the body increases in case of various diseases. Thus, LDH measurement has been proved to serve as a tool for preliminary diagnosis of renal infraction, renal cell carcinoma, skeletal muscle disease, etc.

In this context, the measurement of very low substrate concentrations of the mentioned enzyme (lactate) is of practical importance. The proposed "functionalized carbon nanotubes - Fe3O4 magnetic nanoparticles" nanocomposite enables the oxidative elecrocatalysis of NADH at very low potentials. Finally, the covalent bonding of the NAD+ cofactor and the lactate dehygroenase enzyme upon the synthesized nanocomposite led to the production of a fully integrated bio-sensor for lactate analysis.

"The catalytic property of the invented nanocomposite at very low potentials is due the synergism arising from the combination of the two involved nanostructures (functionalized carbon nanotubes and Fe3O4 magnetic nanoparticles). In addition, another advantage of our proposed system lies in the biocompatibility of the nanocomposite which is in favor of protecting the lactate dehygroenase," Dr. Salimi, a member of the research group, explained.

An elaborate report on this research work has been published in Biosensors and Bioelectronics.

####

For more information, please click here

Copyright © Fars News Agency

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

GLOBALFOUNDRIES and Soitec Enter Into Long-term Supply Agreement on FD-SOI Wafers: Strategic milestone to help guarantee a secure, high-volume supply of FD-SOI technology September 20th, 2017

GLOBALFOUNDRIES Announces Availability of mmWave and RF/Analog on Leading FDX™ FD-SOI Technology Platform: Technology solution delivers ‘connected intelligence’ to next generation high-volume wireless and IoT applications with lower power and significantly reduced cost September 20th, 2017

GLOBALFOUNDRIES Announces Availability of Embedded MRAM on Leading 22FDX® FD-SOI Platform: Advanced embedded non-volatile memory solution delivers ‘connected intelligence’ by expanding SoC capabilities on the 22nm process node September 20th, 2017

Copper catalyst yields high efficiency CO2-to-fuels conversion: Berkeley Lab scientists discover critical role of nanoparticle transformation September 20th, 2017

Nanomedicine

Do titanium dioxide particles from orthopedic implants disrupt bone repair? September 16th, 2017

Arrowhead Hosts Investor & Analyst R&D Day to Introduce TRiM(TM) Platform and Lead RNAi-based Drug Candidates September 14th, 2017

Graphene based terahertz absorbers: Printable graphene inks enable ultrafast lasers in the terahertz range September 13th, 2017

Applications for the nanomedTAB are open until September 18th, 2017 September 13th, 2017

Sensors

Leti Develops Proof of Concept to Test Wireless Systems in Aircraft: Will Present Results of Joint Project at AeroTech Conference And Exhibition in Fort Worth, Texas, Sept. 26-28 September 20th, 2017

Research shows how DNA molecules cross nanopores: Study could inform biosensors, manufacturing, and more September 5th, 2017

Leti and Partners in PiezoMAT Project Develop New Fingerprint Technology for Highly Reliable Security and ID Applications: Ultra-high Resolution Pressure Sensing Uses Matrices of Vertical Piezoelectric Nanowire To Reconstruct the Smallest Features of Human Fingerprints September 5th, 2017

New results reveal high tunability of 2-D material: Berkeley Lab-led team also provides most precise band gap measurement yet for hotly studied monolayer moly sulfide August 26th, 2017

Discoveries

Copper catalyst yields high efficiency CO2-to-fuels conversion: Berkeley Lab scientists discover critical role of nanoparticle transformation September 20th, 2017

Solar-to-fuel system recycles CO2 to make ethanol and ethylene: Berkeley Lab advance is first demonstration of efficient, light-powered production of fuel via artificial photosynthesis September 19th, 2017

A new approach to ultrafast light pulses: Unusual fluorescent materials could be used for rapid light-based communications systems September 19th, 2017

New quantum phenomena in graphene superlattices September 18th, 2017

Announcements

GLOBALFOUNDRIES Delivers 8SW RF SOI Technology for Next-Generation Mobile and 5G Applications: Advanced 8SW 300mm SOI technology enables cost-effective, high-performance RF front-end modules for 4G LTE mobile and sub-6GHz 5G applications September 20th, 2017

GLOBALFOUNDRIES Unveils Vision and Roadmap for Next-Generation 5G Applications: Technology platforms are uniquely positioned to enable a new era of ‘connected intelligence’ with the transition to 5G September 20th, 2017

GLOBALFOUNDRIES Delivers Custom 14nm FinFET Technology for IBM Systems: Jointly developed 14HP process is world’s only technology that leverages both FinFET and SOI September 20th, 2017

GLOBALFOUNDRIES Introduces New 12nm FinFET Technology for High-Performance Applications September 20th, 2017

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project