Nanotechnology Now

Our NanoNews Digest Sponsors


Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Electronic nose out in front

Abstract:
Chemical sensors are exceedingly good at detecting a single substance or a class of chemicals, even at highly rarified concentrations. Biological noses, however, are vastly more versatile and capable of discriminating subtle cues that would confound their engineered counterparts. Unfortunately, even highly trained noses do leave a certain ambiguity when relaying a signal and are not particularly suited for work in specialized situations like operating rooms. A new DNA-based chemical sensor appears to be both extremely sensitive and discerning, making it an important stride on the path to an all-electronic nose.

Electronic nose out in front

College Park, MD | Posted on May 2nd, 2012

A team of researchers report in a paper published in the American Institute of Physics' journal AIP Advances that specially tailored strands of DNA attached to carbon nanotubes can tell the difference between very similar molecules, even those that have an identical chemical makeup. "We're trying to develop this into an electronic nose system," says A.T. Charlie Johnson, a physicist at the University of Pennsylvania and study co-author. "We used this system to distinguish between optical isomers, molecules that are nearly identical except that one is structurally reversed - a mirror image."

The system works by affixing DNA strands to carbon nanotubes, which are excellent electrical conductors. The DNA strands have been fine-tuned to respond to particular chemicals, so when strands come in contact with a target chemical - even at very low concentrations - it produces a measurable electrical signal along the nanotube. The sensors were able to check for molecules that differ by as little as one carbon atom. Though the researchers are not the first to observe this effect, they have achieved an unprecedented level of differentiation for an all-electronic chemical detector. "What I'm focusing on is the size of the difference in the signal," says Johnson.

The researchers are next interested in creating something akin to an actual electronic nose consisting of many individual DNA-based sensors performing the same role as an olfactory receptor. The goal is to have a system that is highly versatile and sensitive with wide-scale applications. For example, the chemical dimethylsulfone is associated with skin cancer. The human nose cannot detect this volatile but it could be detected with the new sensor at concentrations as low as 25 parts per billion.

Acknowledgements: This work was supported by the Army Research Office and by the Nano/Bio Interface Center through the National Science Foundation.

Article: "DNA-decorated carbon nanotube-based FETs as ultrasensitive chemical sensors: Discrimination of homologues, structural isomers, and optical isomers" is published in AIP Advances.

Authors: S.M. Khamis (1), R.A. Jones (1), A.T. Charlie Johnson (1), G. Preti (2,3), J. Kwak (2), and A. Gelperin (2,4).

(1) Department of Physics and Astronomy, University of Pennsylvania, Philadelphia
(2) Monell Chemical Senses Center, Philadelphia
(3) Department of Dermatology, University of Pennsylvania
(4) Princeton Neuroscience Institute, Princeton University, New Jersey

####

For more information, please click here

Contacts:
Charles Blue

301-209-3091

Copyright © American Institute of Physics

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Superheroes are real: Ultrasensitive nonlinear metamaterials for data transfer June 25th, 2016

Russian physicists create a high-precision 'quantum ruler': Physicists have devised a method for creating a special quantum entangled state June 25th, 2016

Nanoscientists develop the 'ultimate discovery tool': Rapid discovery power is similar to what gene chips offer biology June 25th, 2016

Ultrathin, flat lens resolves chirality and color: Multifunctional lens could replace bulky, expensive machines June 25th, 2016

Govt.-Legislation/Regulation/Funding/Policy

Nanoscientists develop the 'ultimate discovery tool': Rapid discovery power is similar to what gene chips offer biology June 25th, 2016

Ultrathin, flat lens resolves chirality and color: Multifunctional lens could replace bulky, expensive machines June 25th, 2016

Particle zoo in a quantum computer: First experimental quantum simulation of particle physics phenomena June 23rd, 2016

Titan shines light on high-temperature superconductor pathway: Simulation demonstrates how superconductivity arises in cuprates' pseudogap phase June 22nd, 2016

Nanotubes/Buckyballs/Fullerenes

Nanotubes' 'stuffing' as is: A scientist from the Lomonosov Moscow State University studied the types of carbon nanotubes' 'stuffing' June 2nd, 2016

Programmable materials find strength in molecular repetition May 23rd, 2016

Nanotubes are beacons in cancer-imaging technique: Rice University researchers use spectral triangulation to pinpoint location of tumors May 21st, 2016

Unveiling the electron's motion in a carbon nanocoil: Development of a precise resistivity measurement system for quasi-one-dimensional nanomaterials using a focused ion beam May 16th, 2016

Sensors

Researchers discover new chemical sensing technique: Technique allows sharper detail -- and more information -- with near infrared light June 24th, 2016

Artificial synapse rivals biological ones in energy consumption June 21st, 2016

A new form of hybrid photodetectors with quantum dots and graphene June 19th, 2016

Drum beats from a one atom thick graphite membrane June 15th, 2016

Discoveries

Superheroes are real: Ultrasensitive nonlinear metamaterials for data transfer June 25th, 2016

Russian physicists create a high-precision 'quantum ruler': Physicists have devised a method for creating a special quantum entangled state June 25th, 2016

Nanoscientists develop the 'ultimate discovery tool': Rapid discovery power is similar to what gene chips offer biology June 25th, 2016

Ultrathin, flat lens resolves chirality and color: Multifunctional lens could replace bulky, expensive machines June 25th, 2016

Announcements

Superheroes are real: Ultrasensitive nonlinear metamaterials for data transfer June 25th, 2016

Russian physicists create a high-precision 'quantum ruler': Physicists have devised a method for creating a special quantum entangled state June 25th, 2016

Nanoscientists develop the 'ultimate discovery tool': Rapid discovery power is similar to what gene chips offer biology June 25th, 2016

Ultrathin, flat lens resolves chirality and color: Multifunctional lens could replace bulky, expensive machines June 25th, 2016

Military

Nanoscientists develop the 'ultimate discovery tool': Rapid discovery power is similar to what gene chips offer biology June 25th, 2016

Ultrathin, flat lens resolves chirality and color: Multifunctional lens could replace bulky, expensive machines June 25th, 2016

Scientists engineer tunable DNA for electronics applications June 21st, 2016

Marrying superconductors, lasers, and Bose-Einstein condensates: Chapman University Institute for Quantum Studies (IQS) member Yutaka Shikano, Ph.D., recently had research published in Scientific Reports June 20th, 2016

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







Car Brands
Buy website traffic