Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > NIST/UMass Study Finds Evidence Nanoparticles May Increase Plant DNA Damage

Graphic showing that increasing exposure to cupric oxide bulk particles (BPs) and nanoparticles (NPs) by radish plants also increases the impact on growth with NPs showing the largest impact. From left to right, the exposure concentrations are 0; 100 parts per million (ppm) BPs; 1,000 ppm BPs; 100 ppm NPs; and 1,000 ppm NPs (showing a severely stunted plant).
Credit: H. Wang, U.S. Environmental Protection Agency
Graphic showing that increasing exposure to cupric oxide bulk particles (BPs) and nanoparticles (NPs) by radish plants also increases the impact on growth with NPs showing the largest impact. From left to right, the exposure concentrations are 0; 100 parts per million (ppm) BPs; 1,000 ppm BPs; 100 ppm NPs; and 1,000 ppm NPs (showing a severely stunted plant).

Credit: H. Wang, U.S. Environmental Protection Agency

Abstract:
Researchers at the National Institute of Standards and Technology (NIST) and the University of Massachusetts Amherst (UMass) have provided the first evidence that engineered nanoparticles are able to accumulate within plants and damage their DNA. In a recent paper,* the team led by NIST chemist Bryant C. Nelson showed that under laboratory conditions, cupric oxide nanoparticles have the capacity to enter plant root cells and generate many mutagenic DNA base lesions.

NIST/UMass Study Finds Evidence Nanoparticles May Increase Plant DNA Damage

Gaithersburg, MD | Posted on April 19th, 2012

The team tested the man-made, ultrafine particles between 1 and 100 nanometers in size on a human food crop, the radish, and two species of common groundcovers used by grazing animals, perennial and annual ryegrass. This research is part of NIST's work to help characterize the potential environmental, health and safety (EHS) risks of nanomaterials, and develop methods for identifying and measuring them.

Cupric oxide (also known as copper (II) oxide or CuO) is a compound that has been used for many years as a pigment for coloring glass and ceramics, as a polish for optics, and as a catalyst in the manufacture of rayon. Cupric oxide also is a strong conductor of electric current, a property enhanced at the nanoscale level, which makes the nanoparticle form useful to semiconductor manufacturers.

Because cupric oxide is an oxidizing agent—a reactive chemical that removes electrons from other compounds—it may pose a risk. Oxidation caused by metal oxides has been shown to induce DNA damage in certain organisms. What Nelson and his colleagues wanted to learn was whether nanosizing cupric oxide made the generation and accumulation of DNA lesions more or less likely in plants. If the former, the researchers also wanted to find out if nanosizing had any substantial effects on plant growth and health.

To obtain the answers, the NIST/UMass researchers first exposed radishes and the two ryegrasses to both cupric oxide nanoparticles and larger sized cupric oxide particles (bigger than 100 nanometers) as well as to simple copper ions. They then used a pair of highly sensitive spectrographic techniques** to evaluate the formation and accumulation of DNA base lesions and to determine if and how much copper was taken up by the plants.

For the radishes, twice as many lesions were induced in plants exposed to nanoparticles as were in those exposed to the larger particles. Additionally, the cellular uptake of copper from the nanoparticles was significantly greater than the uptake of copper from the larger particles. The DNA damage profiles for the ryegrasses differed from the radish profiles, indicating that nanoparticle-induced DNA damage is dependent on the plant species and on the nanoparticle concentration.

Finally, the researchers showed that cupric oxide nanoparticles had a significant effect on growth, stunting the development of both roots and shoots in all three plant species tested. The nanoparticle concentrations used in this study were higher than those likely to be encountered by plants under a typical soil exposure scenario.

"To our knowledge, this is first evidence that there could be a 'nano-based effect' for cupric oxide in the environment where size plays a role in the increased generation and accumulation of numerous mutagenic DNA lesions in plants," Nelson says.

Next up for Nelson and his colleagues is a similar study looking at the impact of titanium dioxide nanoparticles—such as those used in many sunscreens—on rice plants.

* D.H. Atha, H. Wang, E.J. Petersen, D. Cleveland, R.D. Holbrook, P. Jaruga, M. Dizdaroglu, B. Xing and B.C. Nelson. Copper oxide nanoparticle mediated DNA damage in terrestrial plant models. Environmental Science and Technology, Vol. 46 (3): pages 1819-1827 (2012), DOI: 10.1021/es202660k.

** Gas chromatography-mass spectrometry (GC-MS) to detect base lesions and inductively coupled plasma mass spectrometry (ICP-MS) to measure copper uptake.

####

About National Institute of Standards and Technology (NIST)
The National Institute of Standards and Technology (NIST) is an agency of the U.S. Department of Commerce.

For more information, please click here

Contacts:
Michael E. Newman

301-975-3025

Copyright © National Institute of Standards and Technology (NIST)

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Haydale Secures Exclusive Development and Supply Agreement with Tantec A/S: New reactors to be built and commissioned by Tantec A/S represent another step forward towards the commercialisation of graphene October 24th, 2014

QuantumWise guides the semiconductor industry towards the atomic scale October 24th, 2014

MEMS & Sensors Technology Showcase: Finalists Announced for MEMS Executive Congress US 2014 October 23rd, 2014

Nanoparticle technology triples the production of biogas October 23rd, 2014

Laboratories

National Synchrotron Light Source II Achieves 'First Light' October 23rd, 2014

Novel Rocket Design Flight Tested: New Rocket Propellant and Motor Design Offers High Performance and Safety October 23rd, 2014

Govt.-Legislation/Regulation/Funding/Policy

Novel Rocket Design Flight Tested: New Rocket Propellant and Motor Design Offers High Performance and Safety October 23rd, 2014

Strengthening thin-film bonds with ultrafast data collection October 23rd, 2014

Brookhaven Lab Launches Computational Science Initiative:Leveraging computational science expertise and investments across the Laboratory to tackle "big data" challenges October 22nd, 2014

Bipolar Disorder Discovery at the Nano Level: Tiny structures found in brain synapses help scientists better understand disorder October 22nd, 2014

Discoveries

QuantumWise guides the semiconductor industry towards the atomic scale October 24th, 2014

Iranian, Malaysian Scientists Study Nanophotocatalysts for Water Purification October 23rd, 2014

Nanoparticle technology triples the production of biogas October 23rd, 2014

Strengthening thin-film bonds with ultrafast data collection October 23rd, 2014

Announcements

Haydale Secures Exclusive Development and Supply Agreement with Tantec A/S: New reactors to be built and commissioned by Tantec A/S represent another step forward towards the commercialisation of graphene October 24th, 2014

QuantumWise guides the semiconductor industry towards the atomic scale October 24th, 2014

Advancing thin film research with nanostructured AZO: Innovnano’s unique and cost-effective AZO sputtering targets for the production of transparent conducting oxides October 23rd, 2014

Strengthening thin-film bonds with ultrafast data collection October 23rd, 2014

Safety-Nanoparticles/Risk management

Plastic nanoparticles also harm freshwater organisms October 18th, 2014

Human health, wealth require expanded marine science, experts say: In Rome, European experts publish a 'common vision' of priorities for marine research and action through 2020 October 9th, 2014

Coating Nanotubes with Aluminum Oxide Lowers Risk of Lung Injury October 6th, 2014

PEN Inc. Chairman Scott Rickert Announces Company Vision, Product Priorities and Management Team: Webcast Highlights the Launch of PEN October 3rd, 2014

Research partnerships

NYU Researchers Break Nano Barrier to Engineer the First Protein Microfiber October 23rd, 2014

Nanoparticle technology triples the production of biogas October 23rd, 2014

RF Heating of Magnetic Nanoparticles Improves the Thawing of Cryopreserved Biomaterials October 23rd, 2014

Brookhaven Lab Launches Computational Science Initiative:Leveraging computational science expertise and investments across the Laboratory to tackle "big data" challenges October 22nd, 2014

NanoNews-Digest
The latest news from around the world, FREE





  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE