Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > Gold nanoantennas detect proteins: New method of monitoring protein molecules using gold nanoparticles

Institute of Physical Chemistry
The new method developed in Mainz makes it possible to observe individual protein molecules under a microscope with the help of a gold nanoparticle (diagram: Gold nanoantenna with protein molecules shown in purple).
Institute of Physical Chemistry

The new method developed in Mainz makes it possible to observe individual protein molecules under a microscope with the help of a gold nanoparticle (diagram: Gold nanoantenna with protein molecules shown in purple).

Abstract:
Scientists at Johannes Gutenberg University Mainz (JGU) in Germany have developed a new method of observing individual proteins. Detailed knowledge of the dynamics of proteins is necessary in order to understand the related biological processes that occur on the molecular level. To date, this information has been obtained by means of labeling proteins with fluorescent substances, but unfortunately this changes the proteins under investigation and thus influences the biological processes that are to be observed. "Our method allows live tracking of individual proteins without having to label them first," explains Professor Dr. Carsten Sönnichsen of the Institute of Physical Chemistry at JGU. "We are now gaining entirely new insights into molecular processes and can see, for example, how things are constantly in motion even on the very smallest scale."

Gold nanoantennas detect proteins: New method of monitoring protein molecules using gold nanoparticles

Mainz, Germany | Posted on March 14th, 2012

The method developed by the group of Mainz chemists led by Carsten Sönnichsen is based on the use of gold nanoparticles. These serve as glistening nanoantennas that, when they detect individual unlabeled proteins, slightly change their frequency or, in other words, their color. These tiny color changes can be observed using the technique developed in Mainz. "This is an enormous leap forward technologically: We have managed to achieve a very high time resolution for the observation of individual molecules," says Sönnichsen. It is thus now possible to precisely observe the dynamics of a protein molecule down to the millisecond.

The opportunity to detect individual protein molecules also opens up completely new horizons. It has thus become practicable to track the fluctuation of protein population densities and observe protein adsorption processes in real time, among other things. "We can see how molecules move, how they dock at particular locations, and how they fold - this has given us a window into the molecular world," explains Dr. Irene Ament, a member of Sönnichsen's group. This new technology may prove to be useful not only in chemistry but also in medicine and biology.

The work is an important element in research into non-equilibrium phenomena at the molecular level and thus provides a solid foundation for the planned Cluster of Excellence Molecularly Controlled Non-Equilibrium (MCNE), which has been selected to enter the final round of the Excellence Initiative by the German federal and state governments to promote top-level research at German universities. Among other sources, the project received financial support in the form of an ERC Starting Grant for the project "Single metal nanoparticles as molecular sensors" (SINGLESENS).

####

For more information, please click here

Contacts:
Professor Dr. Carsten Sönnichsen
Institute of Physical Chemistry
Johannes Gutenberg University
D 55099 Mainz
Tel +49 6131 39-24313
Fax +49 6131 39-26747

Copyright © Johannes Gutenberg Universitaet Mainz

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Shaping the Future of Nanocrystals: Berkeley Lab Researchers Obtain First Direct Observation of Facet Formation in Nanocubes August 21st, 2014

Hiden Release New Gas Analysis Catalogue August 21st, 2014

Wyatt Technology’s 24th International Light Scattering Colloquium to Highlight Developments in Applications and Characterization of Nanoparticles August 21st, 2014

Water window imaging opportunity: A new theoretical study elucidates mechanisms that could help in producing coherent radiations, ultimately promoting high-contrast imaging of biological samples August 21st, 2014

Govt.-Legislation/Regulation/Funding/Policy

Shaping the Future of Nanocrystals: Berkeley Lab Researchers Obtain First Direct Observation of Facet Formation in Nanocubes August 21st, 2014

Success in Intracellular Imaging of Cesium Distribution in Plants Used for Cesium Absorption August 19th, 2014

Electrical engineers take major step toward photonic circuits: Team invents non-metallic metamaterial that enables them to 'compress' and contain light August 19th, 2014

Promising Ferroelectric Materials Suffer From Unexpected Electric Polarizations: Brookhaven Lab scientists find surprising locked charge polarizations that impede performance in next-gen materials that could otherwise revolutionize data-driven devices August 18th, 2014

Nanomedicine

Ultra-short pulse lasers & Positioning August 21st, 2014

Nanotechnology Helps Production of Super Adsorbent Polymers August 21st, 2014

Newly-Developed Nanobiosensor Quickly Diagnoses Cancer August 20th, 2014

Graphene rubber bands could stretch limits of current healthcare, new research finds August 19th, 2014

Sensors

Newly-Developed Nanobiosensor Quickly Diagnoses Cancer August 20th, 2014

Graphene rubber bands could stretch limits of current healthcare, new research finds August 19th, 2014

Iranian Scientists Stabilize Protein on Highly Stable Electrode Surface August 14th, 2014

Non-Enzyme Nanosensors Quickly Measure Blood Sugar August 12th, 2014

Discoveries

Shaping the Future of Nanocrystals: Berkeley Lab Researchers Obtain First Direct Observation of Facet Formation in Nanocubes August 21st, 2014

Water window imaging opportunity: A new theoretical study elucidates mechanisms that could help in producing coherent radiations, ultimately promoting high-contrast imaging of biological samples August 21st, 2014

Nanotechnology Helps Production of Super Adsorbent Polymers August 21st, 2014

Rice physicist emerges as leader in quantum materials research: Nevidomskyy wins both NSF CAREER Award and Cottrell Scholar Award August 20th, 2014

Announcements

Wyatt Technology’s 24th International Light Scattering Colloquium to Highlight Developments in Applications and Characterization of Nanoparticles August 21st, 2014

Ultra-short pulse lasers & Positioning August 21st, 2014

Malvern’s Dr Alan Rawle talks TLAs in plenary lecture at Particulate Systems Analysis conference August 21st, 2014

Water window imaging opportunity: A new theoretical study elucidates mechanisms that could help in producing coherent radiations, ultimately promoting high-contrast imaging of biological samples August 21st, 2014

Nanobiotechnology

The channel that relaxes DNA: Relaxing DNA strands by using nano-channels: Instructions for use August 20th, 2014

Сalculations with Nanoscale Smart Particles August 19th, 2014

Interaction between Drug, DNA for Designing Anticancer Drugs Studied in Iran August 17th, 2014

Scientists fold RNA origami from a single strand: RNA origami is a new method for organizing molecules on the nanoscale. Using just a single strand of RNA, this technique can produce many complicated shapes. August 14th, 2014

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE