Nanotechnology Now

Our NanoNews Digest Sponsors



Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > FEI Collaborates with NIH to Create New ‘Living Lab’ for Structural Biology Research

Abstract:
Collaboration combines electron microscopy, NMR and X-ray diffraction methods to provide advances in structural biology using cryo-EM to accelerate discoveries about the causes, treatments and cures for disease.

FEI Collaborates with NIH to Create New ‘Living Lab’ for Structural Biology Research

Hillsboro, OR | Posted on January 12th, 2012

FEI (NASDAQ: FEIC) has entered into a Cooperative Research And Development Agreement (CRADA) with the National Institutes of Health (NIH), creating a "Living Lab Structural Biology Center" to promote structural biology research through the integration of cryo-electron microscopy (EM), nuclear magnetic resonance (NMR) spectroscopy, and X-ray diffraction (XRD) which may accelerate important medical discoveries relating to global health challenges such as HIV/AIDS and cancer.



The "Living Lab for Structural Biology," which will be located on the NIH campus, is a unique, interdisciplinary collaboration among experts from FEI and internationally-recognized scientists from the National Cancer Institute (NCI) and the National Institute of Diabetes and Digestive and Kidney Diseases in the fields of cryo-EM, X-ray diffraction (XRD) techniques, nuclear magnetic resonance (NMR) spectroscopy and biochemistry. The research program will be enabled with FEI's Titan Krios™ transmission electron microscope (TEM), the world's most powerful commercially-available electron microscope for structural biology, and continued development of other state-of-the-art technologies necessary to advance the scientific scope of the collaboration.



Dr. Sriram Subramaniam, senior investigator in the Laboratory of Cell Biology of the National Cancer Institute, and a recognized leader in cryo-electron microscopy and related techniques, will serve as director of the Living Lab on the NIH campus. Leading NIH scientists in various other fields, including NMR spectroscopists such as Drs. Adriaan Bax and G. Marius Clore, X-ray crystallographers such as Drs. Fred Dyda and Alex Wlodawer and biochemists such as Drs. Suresh Ambudkar and Stuart Le Grice, will also actively participate in the multi-faceted research program of the Living Lab.



The collaboration involves the development of methods and workflows, from sample preparation through data analysis, which combine information from cryo-EM, XRD, and NMR. Scientists have historically relied on NMR and XRD techniques to determine the structures of molecular complexes and proteins that play a role in the causes of various diseases, such as AIDS, diabetes and cancer. Structural information about a variety of medically important proteins and drugs have been obtained by NMR and XRD methods, however, there are limitations to these techniques which put some of the critical biological answers out of reach. Cryo-EM is a complementary analytical technique that provides near-atomic resolution without requirements for crystallization or limits on molecular size and complexity imposed by the other techniques.



FEI's President and CEO Dr. Don Kania commented, "This collaborative effort with NIH is a critical part of our strategy to provide complete microscopy solutions for life science research. Our Life Sciences business has been increasing rapidly and is a key part of our overall corporate growth plan. Helping our customers obtain increased value from electron microscopy in conjunction with and complementary to XRD and NMR is a key element of that plan."

For more information about the Living Lab, please go to electron.nci.nih.gov or www.fei.com/company/living-lab.aspx.

####

About FEI Company
FEI (Nasdaq: FEIC) is a leading diversified scientific instruments company. It is a premier provider of electron- and ion-beam microscopes and solutions for nanoscale applications across many industries: industrial and academic materials research, life sciences, semiconductors, data storage, natural resources and more. With more than 60 years of technological innovation and leadership, FEI has set the performance standard in transmission electron microscopes (TEM), scanning electron microscopes (SEM) and DualBeams™, which combine a SEM with a focused ion beam (FIB). Headquartered in Hillsboro, Ore., USA, FEI has over 2,000 employees and sales and service operations in more than 50 countries around the world. More information can be found at: www.fei.com.



FEI Safe Harbor Statement

This news release contains forward-looking statements that include statements regarding the performance capabilities and benefits of the Living Lab for Structural Biology. Factors that could affect these forward-looking statements include but are not limited to: failure of the anticipated Living Lab collaboration to function as expected across multiple technologies to accelerate research and development on certain important life sciences issues; failure to manufacture, ship and deliver the tools or software as expected; other specific product or technology failures that could undermine the aims and outcomes of the collaboration; failure of the collaborative team to work together effectively; failure to develop the applications and software required for the collaboration to achieve its research goals or a change in assigned research personnel. Please also refer to our Form 10-K, Forms 10-Q, Forms 8-K and other filings with the U.S. Securities and Exchange Commission for additional information on these factors and other factors that could cause actual results to differ materially from the forward-looking statements. FEI assumes no duty to update forward-looking statements.

For more information, please click here

Contacts:
Sandy Fewkes
(FEI media contact)
MindWrite Communications, Inc
+1 408 224 4024


FEI Company
Fletcher Chamberlin
(FEI investors and analysts)
Investor Relations
+1 503 726 7710

Copyright © FEI Company

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Raman Whispering Gallery Detects Nanoparticles September 1st, 2014

A new, tunable device for spintronics: An international team of scientists including physicist Jairo Sinova from the University of Mainz realises a tunable spin-charge converter made of GaAs August 29th, 2014

Nanoscale assembly line August 29th, 2014

New Vice President Takes Helm at CNSE CMOST: Catherine Gilbert To Lead CNSE Children’s Museum of Science and Technology Through Expansion And Relocation August 29th, 2014

Govt.-Legislation/Regulation/Funding/Policy

New analytical technology reveals 'nanomechanical' surface traits August 29th, 2014

New Vice President Takes Helm at CNSE CMOST: Catherine Gilbert To Lead CNSE Children’s Museum of Science and Technology Through Expansion And Relocation August 29th, 2014

Leading European communications companies and research organizations have launched an EU project developing the future 5th Generation cellular mobile networks August 28th, 2014

New technique uses fraction of measurements to efficiently find quantum wave functions August 28th, 2014

Nanomedicine

Nanoscale assembly line August 29th, 2014

Copper shines as flexible conductor August 29th, 2014

Novel 'butterfly' molecule could build new sensors, photoenergy conversion devices August 28th, 2014

PetLife Comments on CNN Story on Scorpion Venom Health Benefits August 27th, 2014

Announcements

Raman Whispering Gallery Detects Nanoparticles September 1st, 2014

Nanoscale assembly line August 29th, 2014

New analytical technology reveals 'nanomechanical' surface traits August 29th, 2014

New Vice President Takes Helm at CNSE CMOST: Catherine Gilbert To Lead CNSE Children’s Museum of Science and Technology Through Expansion And Relocation August 29th, 2014

New-Contracts/Sales/Customers

East China University of Science and Technology Purchases Nanonex Advanced Nanoimprint Tool NX-B200 July 30th, 2014

University of Manchester selects Anasys AFM-IR for coatings and corrosion research July 30th, 2014

STFC takes delivery of the 100th Hitachi Tabletop SEM in the UK July 3rd, 2014

University of Maastricht Adds Complete Correlative Workflow from FEI to its Institute of Nanoscopy June 23rd, 2014

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE