Nanotechnology Now

Our NanoNews Digest Sponsors



Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > “Reversing the problem" clarifies molecular structure: Noise-free spectroscopy

Abstract:
Optical techniques enable us to examine single molecules, but do we really understand what we are seeing? After all, the fuzziness caused by effects such as light interference makes these images very difficult to interpret. Researchers at the University of Twente's MESA+ Institute for Nanotechnology adopted a "reverse" approach to spectroscopy which cleaned up images by eliminating background noise. The researchers presented their findings in Physical Review Letters.

“Reversing the problem" clarifies molecular structure: Noise-free spectroscopy

Enschede, The Netherlands | Posted on December 23rd, 2011

Rather than starting with the laser beam, the trick is to take the molecule you are studying as the starting point. This radical "reversal" led to a relatively simple modification of conventional CARS spectroscopy, which delivered better images. CARS was already a powerful technique which used lasers to visualize molecules for such purposes as food testing and medical imaging. One advantage is that no fluorescent labels are needed to make the molecules visible. However, background noise complicates the task of interpreting the resultant images. This new approach eliminates such noise completely, leaving only the "real" image. More information than ever before, such as accurate details of the substance's concentration, can be obtained using this technique. It is easier to detect the signature of the molecule in question.

Energy

The key to side-stepping the overwhelming complexity involved lay in Prof. Shaul Mukamel's exhortation to just "Look at the molecule!" (the professor, who holds a post at the University of California, collaborated on the present publication). So don't focus on the way that light interacts with the molecule, as this makes it very difficult - even impossible - to "separate the wheat from the chaff" and reveal the real image. Instead, start by examining the energy levels inside the molecule. Previous work, based on Prof. Mukamel's exhortation, has mainly led to the development of new theories. The University of Twente researchers have now translated this theory into the new technique of Vibrational Molecular Interferometry, which will vastly expand the uses of CARS and other techniques.

This study was conducted in Prof. Jennifer Herek's Optical Sciences group. The research group is part of the MESA+ Institute for Nanotechnology of the University of Twente. The study was funded in part by the Foundation for Fundamental Research on Matter (FOM), and partly from the VICI grant previously awarded to Jennifer Herek by the Netherlands Organisation for Scientific Research (NWO).
The publication, entitled "Background-free nonlinear microspectroscopy with vibrational molecular interferometry", by Erik Garbacik, Jeroen Korterik, Cees Otto, Shaul Mukamel, Jennifer Herek and Herman Offerhaus, was published on 16 December, in the online edition of Physical Review Letters.

####

For more information, please click here

Contacts:
Wiebe van der Veen
tel. +31-(0)53-4894244

Copyright © University of Twente

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Engineers show light can play seesaw at the nanoscale: Discovery is another step toward faster and more energy-efficient optical devices for computation and communication September 22nd, 2014

New chip promising for tumor-targeting research September 22nd, 2014

Twisted graphene chills out: When two sheets of graphene are stacked in a special way, it is possible to cool down the graphene with a laser instead of heating it up, University of Manchester researchers have shown September 22nd, 2014

New star-shaped molecule breakthrough: Scientists at The University of Manchester have generated a new star-shaped molecule made up of interlocking rings, which is the most complex of its kind ever created September 22nd, 2014

Imaging

IEEE International Electron Devices Meeting To Celebrate 60th Anniversary as The Leading Technical Conference for Advanced Semiconductor Devices September 18th, 2014

FEI Opens New Technology Center in Czech Republic: FEI expands its presence in Brno with the opening of a new, larger facility September 18th, 2014

New NPZ100-403 Piezo Stage from nPoint Inc. September 17th, 2014

New non-invasive technique could revolutionize the imaging of metastatic cancer September 17th, 2014

Discoveries

Engineers show light can play seesaw at the nanoscale: Discovery is another step toward faster and more energy-efficient optical devices for computation and communication September 22nd, 2014

New chip promising for tumor-targeting research September 22nd, 2014

Twisted graphene chills out: When two sheets of graphene are stacked in a special way, it is possible to cool down the graphene with a laser instead of heating it up, University of Manchester researchers have shown September 22nd, 2014

New star-shaped molecule breakthrough: Scientists at The University of Manchester have generated a new star-shaped molecule made up of interlocking rings, which is the most complex of its kind ever created September 22nd, 2014

Announcements

Engineers show light can play seesaw at the nanoscale: Discovery is another step toward faster and more energy-efficient optical devices for computation and communication September 22nd, 2014

New chip promising for tumor-targeting research September 22nd, 2014

Twisted graphene chills out: When two sheets of graphene are stacked in a special way, it is possible to cool down the graphene with a laser instead of heating it up, University of Manchester researchers have shown September 22nd, 2014

New star-shaped molecule breakthrough: Scientists at The University of Manchester have generated a new star-shaped molecule made up of interlocking rings, which is the most complex of its kind ever created September 22nd, 2014

Tools

IEEE International Electron Devices Meeting To Celebrate 60th Anniversary as The Leading Technical Conference for Advanced Semiconductor Devices September 18th, 2014

FEI Opens New Technology Center in Czech Republic: FEI expands its presence in Brno with the opening of a new, larger facility September 18th, 2014

New NPZ100-403 Piezo Stage from nPoint Inc. September 17th, 2014

Researchers Create World’s Largest DNA Origami September 11th, 2014

Photonics/Optics/Lasers

Engineers show light can play seesaw at the nanoscale: Discovery is another step toward faster and more energy-efficient optical devices for computation and communication September 22nd, 2014

Twisted graphene chills out: When two sheets of graphene are stacked in a special way, it is possible to cool down the graphene with a laser instead of heating it up, University of Manchester researchers have shown September 22nd, 2014

Toward optical chips: A promising light source for optoelectronic chips can be tuned to different frequencies September 19th, 2014

The Pocket Project will develop a low-cost and accurate point-of-care test to diagnose Tuberculosis: ICN2 holds a follow-up meeting of the Project on September 18th - 19th September 18th, 2014

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE