Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > Marshall University study shows nanoparticles being used as additives in diesel fuels can travel from lungs to liver, causing damage

Abstract:
Recent studies conducted at Marshall University have demonstrated that nanoparticles of cerium oxide—common diesel fuel additives used to increase the fuel efficiency of automobile engines—can travel from the lungs to the liver and that this process is associated with liver damage.

Marshall University study shows nanoparticles being used as additives in diesel fuels can travel from lungs to liver, causing damage

Hunington, WV | Posted on November 17th, 2011

The data in the study by Dr. Eric R. Blough and his colleagues at Marshall's Center for Diagnostic Nanosystems indicate there is a dose-dependent increase in the concentration of cerium in the liver of animals that had been exposed to the nanoparticles, which are only about 1/40,000 times as large as the width of a human hair. These increases in cerium were associated with elevations of liver enzymes in the blood and histological evidence consistent with liver damage. The research was published in the October 13 issue of the peer-reviewed research journal International Journal of Nanomedicine.

Cerium oxide is widely used as a polishing agent for glass mirrors, television tubes and ophthalmic lenses. Cerium oxide nanoparticles are used in the automobile industry to increase fuel efficiency and reduce particulate emissions. Some studies have found that cerium oxide nanoparticles may also be capable of acting as antioxidants, leading researchers to suggest these particles may also be useful for the treatment of cardiovascular disease, neurodegenerative disease and radiation-induced tissue damage.

Blough, the center's director and an associate professor in the university's Department of Biological Sciences, said, "Given the ever-increasing use of nanomaterials in industry and in the products we buy, it is becoming increasingly important to understand if these substances may be harmful. To our knowledge, this is the first report to evaluate if inhaled cerium oxide nanoparticles exhibit toxic effects in the liver."

Dr. Siva K. Nalabotu, the study's lead author and a Ph.D. student in Blough's lab, said, "The potential effects of nanomaterials on the environment and cellular function is not yet well understood. Interest in nanotoxicity is rapidly growing.

"Our studies show that cerium oxide nanoparticles are capable of entering the liver from lungs through the circulation, where they show dose-dependent toxic effects on the liver. Our next step is to determine the mechanism of the toxicity."

The research was supported with funding from the U.S. Department of Energy, grant DE-PS02-09ER09-01.

####

For more information, please click here

Contacts:
Dr. Eric R. Blough

(304) 696-2708

Ginny Painter
Communications Director
Marshall University Research Corporation
304.746.1964

Copyright © Marshall University

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

New exotic phenomena seen in photonic crystals: Researchers observe, for the first time, topological effects unique to an “open” system January 12th, 2018

'Decorated' stem cells could offer targeted heart repair January 11th, 2018

Nanotube fibers in a jiffy: Rice University lab makes short nanotube samples by hand to dramatically cut production time January 11th, 2018

IBM Breaks Records to Top U.S. Patent List for 25th Consecutive Year: IBM Inventors Receive Record 9,043 Patents in 2017 in Areas such as Artificial Intelligence, Cloud, Blockchain, Cybersecurity and Quantum Computing January 11th, 2018

Govt.-Legislation/Regulation/Funding/Policy

New exotic phenomena seen in photonic crystals: Researchers observe, for the first time, topological effects unique to an “open” system January 12th, 2018

'Decorated' stem cells could offer targeted heart repair January 11th, 2018

Nanotube fibers in a jiffy: Rice University lab makes short nanotube samples by hand to dramatically cut production time January 11th, 2018

Laboratory Management Web Application Goes Nationwide January 9th, 2018

Discoveries

New exotic phenomena seen in photonic crystals: Researchers observe, for the first time, topological effects unique to an “open” system January 12th, 2018

'Decorated' stem cells could offer targeted heart repair January 11th, 2018

Nanotube fibers in a jiffy: Rice University lab makes short nanotube samples by hand to dramatically cut production time January 11th, 2018

New oxide and semiconductor combination builds new device potential: Researchers integrated oxide two-dimensional electron gases with gallium arsenide and paved the way toward new opto-electrical devices January 10th, 2018

Announcements

New exotic phenomena seen in photonic crystals: Researchers observe, for the first time, topological effects unique to an “open” system January 12th, 2018

'Decorated' stem cells could offer targeted heart repair January 11th, 2018

Nanotube fibers in a jiffy: Rice University lab makes short nanotube samples by hand to dramatically cut production time January 11th, 2018

IBM Breaks Records to Top U.S. Patent List for 25th Consecutive Year: IBM Inventors Receive Record 9,043 Patents in 2017 in Areas such as Artificial Intelligence, Cloud, Blockchain, Cybersecurity and Quantum Computing January 11th, 2018

Environment

Rice U.'s one-step catalyst turns nitrates into water and air: NSF-funded NEWT Center aims for catalytic converter for nitrate-polluted water January 5th, 2018

'Quantum material' has shark-like ability to detect small electrical signals December 20th, 2017

Silicon Sense first to achieve EPA approval to import detonation nanodiamonds to US: Nanodiamond additives can significantly improve the performance of metal finishing, polymer thermal and mechanical compounds, polymer coatings, CMP polishing and a range of other applications November 29th, 2017

Report highlights opportunities and risks associated with synthetic biology and bioengineering November 22nd, 2017

Automotive/Transportation

STMicroelectronics Selects GLOBALFOUNDRIES 22FDX® to Extend Its FD-SOI Platform and Technology Leadership : GF’s FDX technology will enable ST to deliver high-performance, low-power products for next-generation consumer and industrial applications January 9th, 2018

Study boosts hope for cheaper fuel cells: Rice University researchers show how to optimize nanomaterials for fuel-cell cathodes January 6th, 2018

Novel MOF shell-derived surface modification of Li-rich layered oxide cathode December 29th, 2017

Sandia researchers make solid ground toward better lithium-ion battery interfaces: Reducing the traffic jam in batteries December 13th, 2017

Safety-Nanoparticles/Risk management

How harmful are nano-copper and anti-fungal combinations in the waterways? October 27th, 2017

Do titanium dioxide particles from orthopedic implants disrupt bone repair? September 16th, 2017

Tests show no nanotubes released during utilisation of nanoaugmented materials June 9th, 2017

NanoMONITOR shares its latest developments concerning the NanoMONITOR Software and the Monitoring stations April 21st, 2017

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project