Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > Marshall University study shows nanoparticles being used as additives in diesel fuels can travel from lungs to liver, causing damage

Abstract:
Recent studies conducted at Marshall University have demonstrated that nanoparticles of cerium oxide—common diesel fuel additives used to increase the fuel efficiency of automobile engines—can travel from the lungs to the liver and that this process is associated with liver damage.

Marshall University study shows nanoparticles being used as additives in diesel fuels can travel from lungs to liver, causing damage

Hunington, WV | Posted on November 17th, 2011

The data in the study by Dr. Eric R. Blough and his colleagues at Marshall's Center for Diagnostic Nanosystems indicate there is a dose-dependent increase in the concentration of cerium in the liver of animals that had been exposed to the nanoparticles, which are only about 1/40,000 times as large as the width of a human hair. These increases in cerium were associated with elevations of liver enzymes in the blood and histological evidence consistent with liver damage. The research was published in the October 13 issue of the peer-reviewed research journal International Journal of Nanomedicine.

Cerium oxide is widely used as a polishing agent for glass mirrors, television tubes and ophthalmic lenses. Cerium oxide nanoparticles are used in the automobile industry to increase fuel efficiency and reduce particulate emissions. Some studies have found that cerium oxide nanoparticles may also be capable of acting as antioxidants, leading researchers to suggest these particles may also be useful for the treatment of cardiovascular disease, neurodegenerative disease and radiation-induced tissue damage.

Blough, the center's director and an associate professor in the university's Department of Biological Sciences, said, "Given the ever-increasing use of nanomaterials in industry and in the products we buy, it is becoming increasingly important to understand if these substances may be harmful. To our knowledge, this is the first report to evaluate if inhaled cerium oxide nanoparticles exhibit toxic effects in the liver."

Dr. Siva K. Nalabotu, the study's lead author and a Ph.D. student in Blough's lab, said, "The potential effects of nanomaterials on the environment and cellular function is not yet well understood. Interest in nanotoxicity is rapidly growing.

"Our studies show that cerium oxide nanoparticles are capable of entering the liver from lungs through the circulation, where they show dose-dependent toxic effects on the liver. Our next step is to determine the mechanism of the toxicity."

The research was supported with funding from the U.S. Department of Energy, grant DE-PS02-09ER09-01.

####

For more information, please click here

Contacts:
Dr. Eric R. Blough

(304) 696-2708

Ginny Painter
Communications Director
Marshall University Research Corporation
304.746.1964

Copyright © Marshall University

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Tuning into quantum: Scientists unlock signal frequency control of precision atom qubits July 16th, 2018

Nano-kirigami: 'Paper-cut' provides model for 3D intelligent nanofabrication July 13th, 2018

UMBC researchers develop nanoparticles to reduce internal bleeding caused by blast trauma July 13th, 2018

Oxford Instruments’ 22 Tesla superconducting magnet system commissioned at the UAM, making it the most intense magnetic field available outside a large international facility July 12th, 2018

Govt.-Legislation/Regulation/Funding/Policy

Tuning into quantum: Scientists unlock signal frequency control of precision atom qubits July 16th, 2018

Nano-kirigami: 'Paper-cut' provides model for 3D intelligent nanofabrication July 13th, 2018

Carbon is the new black: Researchers use carbon nanotubes to develop clothing that can double as batteries July 10th, 2018

High-power electronics keep their cool with new heat-conducting crystals July 6th, 2018

Discoveries

Tuning into quantum: Scientists unlock signal frequency control of precision atom qubits July 16th, 2018

Nano-kirigami: 'Paper-cut' provides model for 3D intelligent nanofabrication July 13th, 2018

UMBC researchers develop nanoparticles to reduce internal bleeding caused by blast trauma July 13th, 2018

Barium ruthenate: A high-yield, easy-to-handle perovskite catalyst for the oxidation of sulfides July 13th, 2018

Announcements

Tuning into quantum: Scientists unlock signal frequency control of precision atom qubits July 16th, 2018

Nano-kirigami: 'Paper-cut' provides model for 3D intelligent nanofabrication July 13th, 2018

UMBC researchers develop nanoparticles to reduce internal bleeding caused by blast trauma July 13th, 2018

Barium ruthenate: A high-yield, easy-to-handle perovskite catalyst for the oxidation of sulfides July 13th, 2018

Environment

Nanomaterials could mean more algae outbreaks for wetlands, waterways: High tech metal particles may inadvertently take a toll on aquatic life June 26th, 2018

Squeezing light at the nanoscale: Ultra-confined light could detect harmful molecules June 17th, 2018

A nanotech sensor that turns molecular fingerprints into bar codes June 7th, 2018

Engineered polymer membranes could be new option for water treatment May 6th, 2018

Automotive/Transportation

Leti and Oscaro Partner on Leti’s New Low-Power, Low-Cost Transceiver to Track Parcels July 12th, 2018

GLOBALFOUNDRIES Surpasses $2 Billion in Design Win Revenue on 22FDX® Technology : With 50 client designs and growing, 22FDX proves its value as a cost-effective solution for power-sensitive applications July 9th, 2018

Leti & Partners Launch Pilot Program to Assess New Perception Sensors for Autonomous Vehicles July 5th, 2018

GLOBALFOUNDRIES to Deliver Socionext’s Next Generation Graphics Controller for Advanced In-Vehicle Display Applications: 55nm LPx platform, with SST’s highly reliable embedded SuperFlash®, enables enhanced features and security protection for remote display applications June 28th, 2018

Safety-Nanoparticles/Risk management

Nanomaterials could mean more algae outbreaks for wetlands, waterways: High tech metal particles may inadvertently take a toll on aquatic life June 26th, 2018

NIOSH Releases New Nanotechnology Workplace Design Recommendations March 13th, 2018

How harmful are nano-copper and anti-fungal combinations in the waterways? October 27th, 2017

Do titanium dioxide particles from orthopedic implants disrupt bone repair? September 16th, 2017

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project