Nanotechnology Now

Our NanoNews Digest Sponsors


Heifer International

Wikipedia Affiliate Button

Home > Press > Marshall University study shows nanoparticles being used as additives in diesel fuels can travel from lungs to liver, causing damage

Abstract:
Recent studies conducted at Marshall University have demonstrated that nanoparticles of cerium oxide—common diesel fuel additives used to increase the fuel efficiency of automobile engines—can travel from the lungs to the liver and that this process is associated with liver damage.

Marshall University study shows nanoparticles being used as additives in diesel fuels can travel from lungs to liver, causing damage

Hunington, WV | Posted on November 17th, 2011

The data in the study by Dr. Eric R. Blough and his colleagues at Marshall's Center for Diagnostic Nanosystems indicate there is a dose-dependent increase in the concentration of cerium in the liver of animals that had been exposed to the nanoparticles, which are only about 1/40,000 times as large as the width of a human hair. These increases in cerium were associated with elevations of liver enzymes in the blood and histological evidence consistent with liver damage. The research was published in the October 13 issue of the peer-reviewed research journal International Journal of Nanomedicine.

Cerium oxide is widely used as a polishing agent for glass mirrors, television tubes and ophthalmic lenses. Cerium oxide nanoparticles are used in the automobile industry to increase fuel efficiency and reduce particulate emissions. Some studies have found that cerium oxide nanoparticles may also be capable of acting as antioxidants, leading researchers to suggest these particles may also be useful for the treatment of cardiovascular disease, neurodegenerative disease and radiation-induced tissue damage.

Blough, the center's director and an associate professor in the university's Department of Biological Sciences, said, "Given the ever-increasing use of nanomaterials in industry and in the products we buy, it is becoming increasingly important to understand if these substances may be harmful. To our knowledge, this is the first report to evaluate if inhaled cerium oxide nanoparticles exhibit toxic effects in the liver."

Dr. Siva K. Nalabotu, the study's lead author and a Ph.D. student in Blough's lab, said, "The potential effects of nanomaterials on the environment and cellular function is not yet well understood. Interest in nanotoxicity is rapidly growing.

"Our studies show that cerium oxide nanoparticles are capable of entering the liver from lungs through the circulation, where they show dose-dependent toxic effects on the liver. Our next step is to determine the mechanism of the toxicity."

The research was supported with funding from the U.S. Department of Energy, grant DE-PS02-09ER09-01.

####

For more information, please click here

Contacts:
Dr. Eric R. Blough

(304) 696-2708

Ginny Painter
Communications Director
Marshall University Research Corporation
304.746.1964

Copyright © Marshall University

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

New lithium-oxygen battery greatly improves energy efficiency, longevity: New chemistry could overcome key drawbacks of lithium-air batteries July 26th, 2016

Scientists test nanoparticle drug delivery in dogs with osteosarcoma July 26th, 2016

Nanometrics Reports Second Quarter 2016 Financial Results July 26th, 2016

Ultrasensitive sensor using N-doped graphene July 26th, 2016

Govt.-Legislation/Regulation/Funding/Policy

New lithium-oxygen battery greatly improves energy efficiency, longevity: New chemistry could overcome key drawbacks of lithium-air batteries July 26th, 2016

Scientists test nanoparticle drug delivery in dogs with osteosarcoma July 26th, 2016

Ultrasensitive sensor using N-doped graphene July 26th, 2016

Integration of novel materials with silicon chips makes new 'smart' devices possible July 25th, 2016

Discoveries

New lithium-oxygen battery greatly improves energy efficiency, longevity: New chemistry could overcome key drawbacks of lithium-air batteries July 26th, 2016

Scientists test nanoparticle drug delivery in dogs with osteosarcoma July 26th, 2016

Ultrasensitive sensor using N-doped graphene July 26th, 2016

The NanoWizard® AFM from JPK is applied for interdisciplinary research at the University of South Australia for applications including smart wound healing and how plants can protect themselves from toxins July 26th, 2016

Announcements

New lithium-oxygen battery greatly improves energy efficiency, longevity: New chemistry could overcome key drawbacks of lithium-air batteries July 26th, 2016

Scientists test nanoparticle drug delivery in dogs with osteosarcoma July 26th, 2016

Nanometrics Reports Second Quarter 2016 Financial Results July 26th, 2016

Ultrasensitive sensor using N-doped graphene July 26th, 2016

Environment

A 'smart dress' for oil-degrading bacteria July 24th, 2016

News from Quorum: The College of New Jersey use the Quorum Cryo-SEM preparation system in a project to study ice crystals in high altitude clouds July 19th, 2016

Researchers improve catalyst efficiency for clean industries: Method reduces use of expensive platinum July 8th, 2016

Electronic nose smells pesticides and nerve gas July 6th, 2016

Automotive/Transportation

New lithium-oxygen battery greatly improves energy efficiency, longevity: New chemistry could overcome key drawbacks of lithium-air batteries July 26th, 2016

Researchers improve catalyst efficiency for clean industries: Method reduces use of expensive platinum July 8th, 2016

Artificial synapse rivals biological ones in energy consumption June 21st, 2016

Marrying superconductors, lasers, and Bose-Einstein condensates: Chapman University Institute for Quantum Studies (IQS) member Yutaka Shikano, Ph.D., recently had research published in Scientific Reports June 20th, 2016

Safety-Nanoparticles/Risk management

UK NANOSAFETY GROUP publishes 2nd Edition of guidance to support safe working with nanomaterials May 30th, 2016

PETA science group publishes a review on pulmonary effects of nanomaterials: Archives of Toxicology publishes a review of scientific studies on fibrotic potential of nanomaterials May 26th, 2016

Common nanoparticle has subtle effects on oxidative stress genes May 11th, 2016

Non-animal approach to predict impact of nanomaterials on human lung published Archives of Toxicology publishes workshop recommendations May 2nd, 2016

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







Car Brands
Buy website traffic