Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > Regulating cancer cell migration and invasion using ROS and Cav-1

Abstract:
An investigation by a group of Thai researchers has demonstrated that Caveolin-1 (Cav-1) plays an important role in the migration and invasion of human lung cancer cells and that these effects are regulated by cellular reactive oxygen species (ROS). The group used transfected human lung cancer cells with Cav-1 plasmid which were incubated and cultured prior to performing migration assay.

Regulating cancer cell migration and invasion using ROS and Cav-1

Pathumthani, Thailand | Posted on November 14th, 2011

"The result of this investigation shows the effect of ROS on cell migratory functions is dependent on Cav-1 expression and is associated with Akt activity" said Dr. Ubonthip Nimmannit of National Nanotechnology Center (NANOTEC). "The activation of Akt activity by Cav-1 helps to mediate cancer cell migration and is likely to play an important role in the ROS induced effect on cell motility alteration".

The investigation reveals the differential role of individual ROS on cancer cell mortility and Cav-1 expression helps to better understand tumor progression and metastasis which is considered important in cancer research.

Collaborators on this investigation included Chulalongkorn University, West Virginia University, National Institute for Occupational Safety and Health, West Virginia, and NANOTEC. The researchers reported their investigation in a paper published by the Journal of Biological Chemistry.

####

For more information, please click here

Contacts:
Media contact:
Ramjitti Indaraprasirt
Manager
International Relations Section
NANOTEC
02-564-7100 ext: 6617

Copyright © NANOTEC

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

For 2-D boron, it's all about that base: Rice University theorists show flat boron form would depend on metal substrates September 2nd, 2015

Silk bio-ink could help advance tissue engineering with 3-D printers September 2nd, 2015

Phagraphene, a 'relative' of graphene, discovered September 2nd, 2015

A marine creature's magic trick explained: Crystal structures on the sea sapphire's back appear differently depending on the angle of reflection September 2nd, 2015

Nanomedicine

Silk bio-ink could help advance tissue engineering with 3-D printers September 2nd, 2015

Using DNA origami to build nanodevices of the future September 1st, 2015

Efficiency of Nanodrug Containing Antibiotics in Treatment of Infectious Diseases Evaluated August 31st, 2015

Researchers use DNA 'clews' to shuttle CRISPR-Cas9 gene-editing tool into cells August 30th, 2015

Discoveries

For 2-D boron, it's all about that base: Rice University theorists show flat boron form would depend on metal substrates September 2nd, 2015

Silk bio-ink could help advance tissue engineering with 3-D printers September 2nd, 2015

Phagraphene, a 'relative' of graphene, discovered September 2nd, 2015

A marine creature's magic trick explained: Crystal structures on the sea sapphire's back appear differently depending on the angle of reflection September 2nd, 2015

Announcements

For 2-D boron, it's all about that base: Rice University theorists show flat boron form would depend on metal substrates September 2nd, 2015

Silk bio-ink could help advance tissue engineering with 3-D printers September 2nd, 2015

Phagraphene, a 'relative' of graphene, discovered September 2nd, 2015

A marine creature's magic trick explained: Crystal structures on the sea sapphire's back appear differently depending on the angle of reflection September 2nd, 2015

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







Car Brands
Buy website traffic